Research Projects
Bioinformatic Analysis of Genetic and Genomic Data to Better Understand Disease Pathogenesis and Mechanisms

Programme(s) to which this project applies:

☑ MPhil/PhD ☒ MRes[Med] ☒ URIS
  • Identification of genes associated with systemic lupus erythematosus (SLE), an prototype autoimmune disease.
  • Identification of the immune network underlying SLE through comprehensive analysis of genetic, genomic, and epigenetics data.
  • Functional characterisation of genes associated with SLE through genomic screening and immunological studies.

Prof W Yang, Department of Paediatrics and Adolescent Medicine

Prof Yang received medical training in China and research training in the US before joining the University of Hong Kong in 2006. His research focus on the genetics of complex diseases and Mendelian diseases, making use of data from SNP genotyping, whole exome/genome sequencing, RNA-seq, ATAC-seq, and CRISP-Cas9 screening. Incoming postgraduate students will be working in an environment allowing for learning of both bioinformatic data analysis skills and cutting-edge experimental technologies.

Laboratory Homepage

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.