Research Projects
Innate Immunity in Chronic Kidney Disease

Programme(s) to which this project applies:

☑ MPhil/PhD ☒ MRes[Med] ☒ URIS

Current treatment options for progressive chronic kidney disease (CKD), a major non-communicable disease affecting 10% of the world’s population, are limited. There are two major lines of work to dissect and then target the inflammatory mechanisms of CKD:

  1. establish the role of novel inflammatory targets in in vitro and animal models of CKD, namely cell type-specific toll-like receptor-4 (TLR4) signalling, intrarenal complement activation and tubule specific Wnt/β-catenin signalling, and
  2. define the therapeutic potential of the novel targets by applying specific anti-inflammatory approaches, namely targeting cell- and disease-specific regulatory long non-coding (lnc) RNAs, or via the use of stem cells for tissue repair.

Professor SCW Tang, Department of Medicine

Professor Sydney Tang is currently Chair Professor of Renal Medicine and Yu Professor in Nephrology at the University of Hong Kong. He is known for his contribution to both clinical and basic sciences in nephrology, particularly in realm of diabetic and chronic kidney disease as well as IgA nephropathy.


For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.