Programme(s) to which this project applies:
|☑ MPhil/PhD||☑ MRes[Med]||☑ URIS|
People with mental illness, particularly those with severe mental disorders have markedly increased risk of premature mortality and shortened life expectancy. Major causes of excess death mainly due to physical diseases. However, existing evidence is primarily derived from western countries. There is a paucity of data in Asian regions and Chinese populations. This project aims to systematically examine the impact of mental illness and psychotropic medications on physical health in Hong Kong, utilizing a territory-wide, population-based electronic health-record database. Associations of several major mental illnesses including schizophrenia and related psychotic disorders, bipolar disorder and depression with physical morbidity and mortality risks will be investigated. Empirical data of the current study will facilitate development of mental disorder-specific risk algorithm for physical morbidity and mortality in Chinese populations.
Dr WC Chang, Department of Psychiatry
Dr WC Chang is a Clinical Associate Professor and Department Chairperson of the Department of Psychiatry at the School of Clinical Medicine, LKS Faculty of Medicine and a Principal Investigator of the State Key Laboratory of Brain & Cognitive Sciences, University of Hong Kong. He is a Fellow of the Royal College of Psychiatrists (UK) and the Hong Kong College of Psychiatrists. Dr. Chang’s research interests include early intervention for psychosis, outcomes of schizophrenia and bipolar disorder, clinical high-risk and psychosis prediction, negative symptoms, reinforcement learning and related paradigms for amotivation, as well as the impact of severe mental illnesses on physical health. He has published 190 articles in international peer-reviewed journals, including 64 first-/corresponding authored articles and 4 book chapters. He has been a HKU Scholars in the Top 1% for 4 consecutive years since 2019, and has received several research awards including such as the Early Psychosis Association Young Investigator Award, and the NARSAD Young Investigator Award by Brain & Behavior Research Foundation.
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