Research Projects
Biogenesis and functional diversity of mammalian motile cilia

Motile cilia are chemo- and mechano-sensory organelles essential to the respiratory, nervous, and reproductive systems. In our lab, we combine diverse animal models, single-molecule reconstitution assays, proteomics, tissue expansion, super-resolution microscopy, and in situ cryo-tomography to better understand the evolution, biogenesis, and diverse functions of cilia and cilia-mediated signaling pathways. In this project, we will combine animal models and human PSC derived organoids to understand the roles of ciliary transition zone, a diffusion barrier at the base of cilia, in regulating cilia-mediated cellular heterogeneity pertinent to human diseases. 

Professor M He, School of Biomedical Sciences

Prof. He is combing mouse models and human PSC derived organoids to understand cellular dynamics important for tissue repair and regeneration. 

Biography
Lab Homepage
muhe@hku.hk

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

1. your CV,
2. a brief description of your research interest and experience, and
3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to rpgmed@hku.hk.

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.