Programme(s) to which this project applies:

☑ MPhil/PhD ☑ MRes[Med] ☑ URIS

Objective and Significance:

To improve understanding of immune responses to vaccination in multiple physical sites and in different ages

To apply cutting edge methodologies such as CyTOF, system serology assays, and scRNAseq to study cellular and humoral immune responses in a comprehensive and detailed manner

To provide clinical evidence to support the use of novel vaccines in younger age groups, including healthy children and children with immunocompromise and vaccine seroconversion failure

Research Plan and Methodology:

We have a 3-year immunobridging study on BNT162b2 and CoronaVac in children and adolescents (NCT04800133). A longitudinal study on measles booster vaccination in young adults with secondary vaccine failure has also begun. Other vaccine studies and trials are also underway. For enquiries please liaise with Daniel Leung at

Prof YL Lau, Department of Paediatrics and Adolescent Medicine

Scholars Hub

Professor J Sou Da Rosa Duque, Department of Paediatrics and Adolescent Medicine

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.