Aug 2021
Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study
Lancet Infectious Diseases, In Press
Brief Advice, Nicotine Replacement Therapy Sampling, and Active Referral for Expectant Fathers Who Smoke Cigarettes: A Randomized Clinical Trial
JAMA Internal Medicine, 2021-08-01, Vol. 181 (8), p.1081-1089
Effects of tai chi or conventional exercise on central obesity in middle-aged and order adults
Annals of Internal Medicine, 2021-08, Vol. 174 (8), p.1050-1057
Jul 2021
Ethnicity Associations With Food Sensitization Are Mediated by Gut Microbiota Development in the First Year of Life
Gastroenterology, 2021-07, Vol. 161 (1), p.94-106
May 2021
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
Nature, 2021-05, Vol. 593 (7859), p.418-423
Apr 2021
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies
Cell Host & Microbe, 2021-04-14, Vol. 29 (4), p.511-563
Mar 2021
Aspirin Use and Risk of Colorectal Cancer Among Older Adults
JAMA Oncology, 2021-03-01, Vol.7 (3), p.428-435
Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study
Lancet Public Health, 2021-03-01, Vol. 6(3), p.184-191
Nowcasting epidemics of novel pathogens: lessons from COVID-19
Nature Medicine, 2021-03, Vol. 27, p.388-395
Feb 2021
PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma
Signal Transduction and Targeted Therapy, 2021-02-26, Vol. 6 (1), 86
RSK2-inactivating mutations potentiate MAPK signaling and support cholesterol metabolism in hepatocellular carcinoma
Journal of Hepatology, 2021-02, Vol.74 (2), p.360-371
Trends in Cardiovascular Medicine Use in 65 Middle- and High-Income Countries
Journal of the American College of Cardiology, 2021-02-23, Vol. 77 (7), p. 1021-1023
Jan 2021
PARP inhibitor Olaparib overcomes Sorafenib resistance through reshaping the pluripotent transcriptome in hepatocellular carcinoma
Molecular Cancer, 2021-01-23, 20
Dec 2020
Beta-amyloid deposition around hepatic bile ducts is a novel pathobiological and diagnostic feature of biliary atresia
Journal of Hepatology, 2020-12, Vol.73 (6), p.1391-1403
Letter regarding "A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement"
Journal of Hepatology, 2020-12, Vol. 73 (6), p.1573-1574
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles
Gut, 2020-12, Vol.69 (12), p.2165-2179
Nov 2020
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
The Lancet, 2020-11-07, Vol.396 (10261), p.1511-1524
Oct 2020
Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses
Immunity, 2020, Vol.53, p.864-877
Diverse effects of hepatic steatosis on fibrosis progression and functional cure in virologically quiescent chronic hepatitis B
Journal of Hepatology, 2020-10, Vol.73 (4), p.800-806
Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib: The CheckMate 040 Randomized Clinical Trial
JAMA Oncology, 2020-10-01, Vol.6 (11), e204564
Viral hepatitis and pregnancy
Nature Reviews Gastroenterology & Hepatology (2020)
Sep 2020
Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood–brain barrier
European Heart Journal, 2020-09-01, Vol.41 (33), p.3169-3180
Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong
Nature Medicine (2020)
SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series
The Lancet Infectious Diseases, 2020-09, Vol.20 (9), p.1051-1060
What can we expect from first-generation COVID-19 vaccines?
The Lancet, 2020-09-21, Vol.396 (10261), p.1467-1469
Aug 2020
Allergic contact dermatitis and tracheobronchitis associated with repeated exposure to tear gas
The Lancet, 2020-08-01, Vol.396 (10247), e12
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2
Nature Communications, 2020-12, Vol.11 (1), p.1-10
ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection
Nature Immunology, Volume 21, p.1293–1301(2020)
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
Nature, 2020-08-20, Vol.584 (7821), p.450-456
The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
Nature Reviews Endocrinology, 2020-11, Vol. 16 (11), p.654-667
SARS-CoV-2 infects human neural progenitor cells and brain organoids
Cell Research, 2020-08-04, Vol.30, p.928-931
Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions
Science, 2020-08-28, Vol.369 (6507), p.1106-1109
Jul 2020
Association Between Treatment With Apixaban, Dabigatran, Rivaroxaban, or Warfarin and Risk for Osteoporotic Fractures Among Patients With Atrial Fibrillation: A Population-Based Cohort Study
Annals of Internal Medicine, 2020-07-07, Vol.173 (1), p.1-9
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Nature, 2020-07-24
Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study
The Lancet Infectious Diseases, 2020-07, Vol.20 (7), p.793-802
Seroprevalence of SARS-CoV-2 in Hong Kong Special Administrative Region and our returnees evacuated from Hubei province of China: a multi-cohort study
The Lancet Microbe, 2020-07, Vol.1 (3), p.e111-118
Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures
The Lancet Respiratory Medicine, 2020-07, Vol.8 (7), p.687-695
Jun 2020
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
The Lancet, 2020-06-20, Vol.395 (10241), p.1907-1918
Viral dynamics in mild and severe cases of COVID-19
The Lancet Infectious Diseases, 2020-06, Vol.20 (6), p.656-657
May 2020
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
Science, 2020-05-08, Vol.368 (6491), p.630-633
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study
The Lancet Microbe, 2020-05, Vol.1 (1), p.e14-23
Effect of changing case definitions for COVID-19 on the epidemic curve and transmission parameters in mainland China: a modelling study
The Lancet Public Health, 2020-05, Vol.5 (5), p.e289-e296
Global coordination on cross-border travel and trade measures crucial to COVID-19 response
The Lancet, 2020-05-23, Vol.395 (10237), p.1593-1595
Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study
The Lancet Public Health, 2020-05, Vol.5 (5), p.e279-e288
Infection of bat and human intestinal organoids by SARS-CoV-2
Nature Medicine, Volume 26, p.1077–1083(2020)
Infection of dogs with SARS-CoV-2
Nature, 2020-05-14
Modelling COVID-19
Nature Reviews Physics, Volume 2, p.279–281(2020)
Pathogenesis and transmission of SARS-CoV-2 in golden Syrian hamsters
Nature, Volume 583, p.834–838(2020)
Rational use of face masks in the COVID-19 pandemic
The Lancet Respiratory Medicine, 2020-05, Vol.8(5), p.434-436
Stability of SARS-CoV-2 in different environmental conditions
The Lancet Microbe, 2020-05, Vol.1 (1), p.e10
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study
The Lancet Infectious Diseases, 2020-05, Vol.20 (5), p.565-574
Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
The Lancet, 2020-05-30, Vol.395 (10238), p.1695-1704
Apr 2020
Crowdsourcing data to mitigate epidemics
The Lancet Digital Health, 2020-04, Vol.2 (4), p.e156-157
Clinical Characteristics of Coronavirus Disease 2019 in China
The New England Journal of Medicine, 2020-04-30, Vol.382 (18), p.1708-1720
First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment
The Lancet, 2020, Vol. 395 (10233), p1382–1393
From a Sprint to a Marathon in Hong Kong
The New England Journal of Medicine, 2020-04-30, Vol.382 (18), p.e45
Respiratory virus shedding in exhaled breath and efficacy of face masks
Nature Medicine, Volume 26, p.676–680(2020)
Temporal dynamics in viral shedding and transmissibility of COVID-19
Nature Medicine, Volume 26, p.672–675(2020)
Viral load of SARS-CoV-2 in clinical samples
The Lancet Infectious Diseases, 2020-04, Vol.20(4), p.411-412
Wearing face masks in the community during the COVID-19 pandemic: altruism and solidarity
The Lancet, 2020-04-16, S0140-6736(20)30918-1
Mar 2020
Are high-performing health systems resilient against the COVID-19 epidemic?
The Lancet, 2020-03-14, Vol.395 (10227), p.848-850
Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China
Nature Medicine, Volume 26, p.506–510(2020)
Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins
Nature, Volume 583, p.282–285(2020)
Incidences, temporal trends and risks of hospitalisation for gastrointestinal bleeding in new or chronic low-dose aspirin users after treatment for Helicobacter pylori: a territory-wide cohort study
Gut, 17 March 2020, Vol.69(3), p.445
Mass masking in the COVID-19 epidemic: people need guidance
The Lancet, 2020, Vol.395 (10228), p.945-945
The first 2019 novel coronavirus case in Nepal
The Lancet Infectious Diseases, 2020-03, Vol.20 (3), p.279-280
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Nature Microbiology, Volume 5, p.536–544(2020)
SARS-CoV-2 is an appropriate name for the new coronavirus
The Lancet, 2020-03-21, Vol.395 (10228), p.949-950
SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients
The New England Journal of Medicine, 2020-03-19, Vol.382 (12), p.1177-1179
Feb 2020
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
The Lancet, 2020, Vol.395 (10223), p.514-523
Emergence of a novel human coronavirus threatening human health
Nature Medicine, Volume 26, p.317–319(2020)
Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression
Gut, 22 February 2020, Vol.69(2), p.329
Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study
The Lancet, 2020, Vol. 395 (10225), p689–697
Jan 2020
A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non–Small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early-Stage Disease
Clinical Cancer Research, 1 January 2020, Vol.26(1), pp.282-289
Depression and post-traumatic stress during major social unrest in Hong Kong: a 10-year prospective cohort study
The Lancet (British edition), 2020-01-25, Vol.395 (10220), p.273-284
Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia
The New England Journal of Medicine, 2020, Vol.382 (13), p.1199-1207
Turning influenza vaccinology on its head to reveal the stalk
The Lancet Infectious Diseases, 2020-01, Vol.20 (1), p.5-7
Dec 2019
Intensification with dipeptidyl peptidase-4 inhibitor, insulin, or thiazolidinediones and risks of all-cause mortality, cardiovascular diseases, and severe hypoglycemia in patients on metformin-sulfonylurea dual therapy: A retrospective cohort study
PLoS Medicine, 1 December 2019, Vol.16(12), p.e1002999
Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses
Gastroenterology, December 2019, Vol.157(6), pp.1556-1571.e5
Nov 2019
Upconversion-like Photolysis of BODIPY-Based Prodrugs via a One-Photon Process
Journal of the American Chemical Society, November 6, 2019, Vol.141(44), pp.17482-17486
Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187 897 patients
Gut, 26 November 2019, Vol.68(11), p.1979
Oct 2019
Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
Nature Communications, 15 October 2019, Vol.10(1), pp.4681
Aug 2019
Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9
Nature Methods, August 2019, Vol.16(8), pp.722-730
Jun 2019
Aberrant Super-Enhancer Landscape in Human Hepatocellular Carcinoma
Hepatology, June 2019, Vol.69(6), pp.2502-2517
May 2019
Injectable cell-encapsulating composite alginate-collagen platform with inducible termination switch for safer ocular drug delivery
Biomaterials, May 2019, Vol.201, pp.53-67
Apr 2019
Identifying occult maternal malignancies from 1.93 million pregnant women undergoing noninvasive prenatal screening tests
Genetics in Medicine, Volume 21, p.2293–2302(2019)
Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection
Gastroenterology, April 2019, Vol.156(5), pp.1392-1403.e7
Mar 2019
Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank
BMJ, 06 March 2019, Vol.364
Feb 2019
Trazodone use and risk of dementia: A population-based cohort study
PLoS Medicine, 01 February 2019, Vol.16(2), p.e1002728
Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader
Nature Communications, February 20, 2019, Vol.10(1), p.852
Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer
Nature Communications, February 12, 2019, Vol.10(1), p.716
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
The Journal of Clinical Investigation, February 1, 2019, Vol.129(2), pp.834-849
Jan 2019
Temperature-responsive tungsten doped vanadium dioxide thin film starves bacteria to death
Materials Today, January 2019, Vol.22, pp.35-49
Indirect protection from vaccinating children against influenza in households
Nature Communications, January 10, 2019, Vol.10(1), p.106
Dec 2018
Effectiveness of influenza vaccination on influenza-associated hospitalisations over time among children in Hong Kong: a test-negative case-control study
The Lancet Respiratory Medicine, December 01, 2018, Volume 6, ISSUE 12, P925-934.
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening
Cell Stem Cell, 06 December 2018, Vol.23(6), pp.882-897.e11
Nov 2018
Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures
The Lancet Respiratory Medicine, November 2018, Vol.6(11), pp.846-854
Chronic hepatitis B virus infection
The Lancet, November 24, 2018, Volume 392, ISSUE 10161, P2313-2324
Oct 2018
Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases
The Lancet Psychiatry, October 2018, Vol.5(10), pp.824-835
Jul 2018
Effects of Helicobacter pylori treatment on incidence of gastric cancer in older individuals
Gastroenterology, July 2018, Vol.155(1), pp.67-75
May 2018
Long-term effects of discontinuation from antipsychotic maintenance following first episode schizophrenia and related disorders: a 10 year follow-up of a randomised, double-blind trial
The Lancet Psychiatry, May 2018, Vol.5(5), pp.432-442
Association of an Early Intervention Service for Psychosis With Suicide Rate Among Patients With First-Episode Schizophrenia-Spectrum Disorders
JAMA Psychiatry, 01 May 2018, Vol.75(5), pp.458-464
Mar 2018
Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial
Eur Heart J. 2018 Mar 21;39(12):1028-1037
Jan 2018
Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study Free
Gut, 2018 Jan;67(1):28-35
Characterizing the dynamics underlying global spread of epidemics
Nature Communications, January 2018, Volume 9, Article number: 218
Five-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM) on Diabetes-Related Complications and Health Service Uses—A Population-Based and Propensity-Matched Cohort Study
Diabetes Care, January 2018, Vol.41(1), pp.49-59
Dec 2017
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Gut, 2017 Dec;66(12):2149-2159
Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development
Cell Research, 2017 Dec;27(12):1466-1484
Oct 2017
Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
Nat Commun. 2017 Oct 30;8(1):1185
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease
Nature Genetics, Volume 49, No. 12, Pages 1722-1730, October 2017
Sep 2017
Pooled Analysis of Individual Patient Data on Concurrent Chemoradiotherapy for Stage III Non-Small-Cell Lung Cancer in Elderly Patients Compared With Younger Patients Who Participated in US National Cancer Institute Cooperative Group Studies
Journal of Clinical Oncology, Volume 35, No. 25, Pages 2885-2892, September 2017
The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity
Cell Metab. 2017 Sep 5;26(3):493-508
Aug 2017
TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication
Gut, 2017 Aug;66(8):1496-1506
Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry
Nature Neuroscience, Volume 20, No. 10, Pages 1342-1349, August 2017
Mar 2017
Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study
The Lancet Infectious Diseases, Volume 17, ISSUE 3, P339-347, March 01, 2017
Dec 2016
Fractional dosing of yellow fever vaccine to extend supply: a modelling study
The Lancet, Volume 388, No. 10062, Pages 2904–2911, December 2016
Oct 2016
Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia
Science Translational Medicine, Vol. 8, Issue 359, pp. 359ra129, October 5, 2016
Aug 2016
Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
Nature Genetics, Volume 48, No 8, Pages 940–946, August 2016
Jun 2016
Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe-/- Mice
Circulation, Volume 133, Issue 24, Pages 2434-2446, June 2016
Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin
JAMA Intern Med, Volume 176, Issue 6, Pages 828-834, June 2016
RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation
Gut, 66(9):1645-1656, September 2017, Epub 2016 Jun 21
Mar 2016
Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis
PLOS Medicine, Volume 13, No 3, March 2016
Feb 2016
Quantifying influenza virus diversity and transmission in humans
Nature Genetics (Letter), Volume 48, No 2, Pages 195-200, February 2016
Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial
The Lancet Infectious Diseases, Volume 16, No. 2, p209–218, February 2016.
Jan 2016
Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia
Science, Vol. 351, Issue 6268, pp. 81-84, 01 Jan 2016 (On-line print17 Dec 2015).
Oct 2015
Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair
Molecular Cell (October 2015), Volume 60, Issue 1, p163-176
Sep 2015
Prevention of Dabigatran-Related Gastrointestinal Bleeding With Gastroprotective Agents: A Population-Based Study
Gastroenterology, Volume 149, Issue 3, Pages 586–595, September 2015.
Clinical Benefit of Warfarin in Dialysis Patients With Atrial Fibrillation
Journal of the American College of Cardiology, Volume 66, Issue 11, Pages 1310-1311, 15 September 2015.
Aug 2015
Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice
Gastroenterology, Vol. 149, Issue 7, p1837–1848, Published online: August 7 2015.
Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation
Cell Metabolism, Volume 22, Issue 2, p279–290, 4 August 2015.
Impact of Secondhand Smoke Exposure on Smoking Cessation in Cardiac Patients
Journal of the American College of Cardiology, Volume 66, Issue 5, 592-3, August 2015
Jun 2015
Dissemination, divergence and establishment of H7N9 influenza viruses in China
Nature, Volume 522, Issue 7554, 102–105, 04 June 2015.
May 2015
Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice
Circulation, 2015 May 26;131(21):1861-71.
Apr 2015
One More “C” for CHA2DS2-VASc Score?
Journal of the American College of Cardiology, Volume 65, Issue 15, Pages 1602-1603, 21 April 2015.
Oct 2013
The genesis and source of the H7N9 influenza viruses causing human infections in China
Nature, 502 (7470) : 241–244, October 2013
Sept 2013
Prognostic Value of Preoperative Right Ventricular Geometry and Tricuspid Valve Tethering Area in Patients Undergoing Tricuspid Annuloplasty
Circulation, September 2013 (online published).
Aug 2013
Prospective Randomized Study to Assess the Efficacy of Site and Rate of Atrial Pacing on Long-term Progression of Atrial Fibrillation in Sick Sinus Syndrome- Septal Pacing for Atrial Fibrillation Suppression Evaluation (SAFE) study.
Circulation, 128 (7) : 687-93, August 2013.
Reducing Treatment Decision Conflict Difficulties in Breast Cancer Surgery: A Randomized Controlled Trial
Journal of Clinical Oncology, 31 (23) : 2879-2885, August 2013.
Jul 2013
Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases
The Lancet, 382 (9887), 129 - 137, July 2013.
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity
The Lancet, 382 (9887) : 138–145, July 2013.
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs.
Science. Vol. 341, Issue 6142, pp. 183-186, 12 Jul 2013.
Jun 2013
Association between adverse clinical outcome in human disease caused by novel infl uenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance
The Lancet, 381 (9885) : 2273–2279, June 2013.
Detection of mild to moderate influenza A/H7N9 infection by China’s national sentinel surveillance system for influenza-like illness: case series
British Medical Journal, 346 : 3693, June 2013.
Apr 2013
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
Nature, 496 (7443) : 110–113, April 2013.
Feb 2013
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
Nature Medicine, 19 (2) : 209 - 216, February 2013
Nov 2011
Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
Science, 334 (6057) : 806-809, November 2011
Oct 2011
Estimating Infection Attack Rates and Severity in Real Time during an Influenza Pandemic: Analysis of Serial Cross-Sectional Serologic Surveillance Data
PLoS Medicine, 8 (10): e1001103, October 2011.
Sequential Establishment of Stripe Patterns in an Expanding Cell Population
Science, 334 (6053) : 238-241, October 2011
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Nature Genet, 43 (12) : 1219-23, Oct 2011
Sep 2011
Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida
Science, 333 (6050) : 1761-1764, September 2011.
Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans.
J Clin Invest, Volume 121, Issue 9 : 3467-78, September 1, 2011.
Jun 2011
CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation
Cell Stem Cell, 9 (1) : 50–63, July 2011.
Epidemiological Characteristics of 2009 (H1N1) Pandemic Influenza Based on Paired Sera from a Longitudinal Community Cohort Study
PLoS Medicine, 8 (6): e1000442, June 2011.
Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score
The Lancet Oncology, 12 (6): 568-574, June 2011.
May 2011
Long-term evolution and transmission dynamics of swine influenza A virus
Nature, 473 (7348) : 519–522, May 2011
Dec 2010
miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1
Cell Stem Cell, 7 : 6, 694-707, December 2010
A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
Cell Stem Cell, 8 (1): 31-45, December 2010.
Oct 2010
SOX9 induces and maintains neural stem cells
Nature Neuroscience, 13 (10) : 1181–1189, October 2010
Aug 2010
Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial
British Medical Journal, 341 : 4024, August 2010
Effect of an Advocacy Intervention on Mental Health in Chinese Women Survivors of Intimate Partner Violence: A Randomized Controlled Trial
Journal of the American Medical Association, 304 : 5, 536-543, August 2010
Jun 2010
Identification of influenza A nucleoprotein as an antiviral target
Nature Biotechnology, 28 : 6, 600–605, June 2010
Reassortment of Pandemic H1N1/2009 Influenza A Virus in Swine
Science, 328, 1529, June 2010
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
Cell Stem Cell, 6 : 6, 603-615, June 2010
Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households
The New England Journal Medicine, 362 : 2175-2184, June 2010
Mar 2010
Functional Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Attenuate Limb Ischemia in Mice
Circulation, 121 (9):1113-1123, March 2010
Regulation of Chromatin Architecture by the PWWP Domain-Containing DNA Damage-Responsive Factor EXPAND1/MUM1
Molecular Cell 37 (6) : 854–864, March 2010
Dec 2007
Telbivudine versus Lamivudine in Patients with Chronic Hepatitis B
The New England Journal of Medicine. 357 : 25, :2576 - 88, 20 December 2007.
Oct 2007
Protein arginine-methyltransferase-dependent oncogenesis
Nature Cell Biology, v. 9, (10), p. 1208-31215, October 2007.
Treatment with Convalescent Plasma for Influenza A (H5N1) Infection
The New England Journal of Medicine, 357 : 14, 1450-1451, October 4, 2007.
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.
Nature Medicine, 13 : 10, 1228-1233, October 2007.
Apr 2007
Omeprazole before Endoscopy in Patients with Gastrointestinal Bleeding
The New England Journal of Medicine, 356 : 16, 1631-1640, April 2007.
Mar 2007
Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict the Development of the Metabolic Syndrome: A 5-Year Prospective Study
Circulation, Volume 115, Issue 12, p.1537-1543, March 27, 2007.
Intervertebral disc transplantation in the treatment of degenerative spine disease: a preliminary study.
The Lancet, 369: 9566, 993-999, March 2007
Feb 2007
Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract.
Nature Medicine, 13 : 2, 147-149, February 2007.
Nov 2006
Effect of obesity in patients with coronary artery disease
The Lancet, 368 : 9548, 1645-1645, November 2006
Oct 2006
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
Nature Genetics, 38 : 10, 1178-1183, October 2006
Sep 2006
Bioartificial Sinus Node Constructed via In Vivo Gene Transfer of an Engineered Pacemaker HCN Channel Reduces the Dependence on Electronic Pacemaker in a Sick-Sinus Syndrome Model
Circulation, Volume 114, Issue 10, p.1000-11, September 5, 2006.
Reducing the impact of the next influenza pandemic using household-based public health interventions
PLoS Medicine, Volume 3, Issue 9, p.1532-1540, September 2006.
Jul 2006
The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication
Nature Cell Biology, 8, 717 – 724, July 2006
Apr 2006
Influenza-Associated Hospitalization in a Subtropical City
PLoS Medicine, Volume 3, Issue 4, p.485-492, April 2006.
Mar 2006
Cytotoxic therapy for severe avian influenza A (H5N1) infection
The Lancet, 367 : 9513, 870-873, March 2006
Entecavir versus Lamivudine for Patients with HBeAg-Negative Chronic Hepatitis B
The New England Journal of Medicine, 354 : 10, 1011-1020, March 2006
Feb 2006
Clozapine Alone versus Clozapine and Risperidone with Refractory Schizophrenia
The New England Journal of Medicine,. 354 : 5, p. 472-482, February 2006.
White Matter Anisotropy in Post-Treatment Childhood Cancer Survivors: Preliminary Evidence of Association With Neurocognitive Function
Journal of Clinical Oncology, v.24, (6), p,884-890, February 2006.
Jan 2006
Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection
Nature Genetics, 38 : 1, 38-46, January 2006
Aug 2005
H5N1 influenza pandemic: contingency plans
The Lancet, 366 : 9485, 533-534, August 2005
Jul 2005
Avian flu: H5N1 virus outbreak in migratory waterfowl
Nature, 436 : 191-192, July 2005
Genomic instability in laminopathy-based premature aging
Nature Medicine, 11 : 7, 780-785, July 2005
Jun 2005
Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B
The New England Journal of Medicine, 352 : 26, 2682-2695, June 2005
Apr 2005
Sox2 is required for sensory organ development in the mammalian inner ear
Nature, 434 : 1031-1035, April 2005
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
Proc Natl Acad Sci, 102 : 17, 6086-6091, April 2005
Dec 2004
Severe acute respiratory syndrome
Nature Medicine, 10 : 12, S88-S97, December 2004
Jul 2004
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia
Nature, 430 : 209-213, July 2004
Jun 2004
Association of Laribacter hongkongensis in community-acquired gastroenteritis with travel and eating fish: a multicentre case-control study
The Lancet, 363 : 1941-47, June 2004
Jan 2004
Helicobacter pylori Eradication to Prevent Gastric Cancer in a High-Risk Region of China
Journal of the American Medical Association, 291 : 2, 187-194, January 2004
Oct 2003
Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China
Science, 302 : 5643, 276-278, October 2003
Jul 2003
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
Journal of Clinical Investigation, 112 : 1, 91-100, July 2003
Jun 2003
Transmission Dynamics of the Etiological Agent of SARS in Hong Kong: Impact of Public Health Interventions
Science, 300 : 5627, 1961-1966, June 2003
May 2003
Development of a standard treatment protocol for severe acute respiratory syndrome
The Lancet, 361 : 9369, 1615-1617, May 2003
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study
The Lancet, 361 : 9371, 1767-1772, May 2003
Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS)
The Lancet, 361 : 9368, 1519-1520, May 2003
Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong
The Lancet, 361 : 9371, 1761-1766, May 2003
Lung pathology of fatal severe acute respiratory syndrome
The Lancet, 361 : 9371, 1773-1778, May 2003
A Cluster of Cases of Severe Acute Respiratory Syndrome in Hong Kong
The New England Journal of Medicine, 348 : 20, 1977-1985, May 2003
Apr 2003
Coronavirus as a possible cause of severe acute respiratory syndrome
The Lancet, 361 : 9366, 1319-1325, April 2003
Jan 2003
Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation
The Lancet, 361 : 9351, 47-49, January 2003
Dec 2002
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
The Lancet, 360 : 9348, 1831-1837, December 2002
Influenza-related hospitalizations among children in Hong Kong
The New England Journal of Medicine, 347 : 26, 2097-2103, December 2002
Nov 2002
Cardiorespiratory and all-cause mortality after restrictions on sulphur content of fuel in Hong Kong: an intervention study
The Lancet, 360 : 9346, 1646-1652, November 2002
Jun 2002
A Genetic Locus for Adolescent Idiopathic Scoliosis Linked to Chromosome 19p13.3
American Journal of Human Genetics, 71 : 401-406, June 2002
Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR
Proc Natl Acad Sci, 99 : 13, 8950-8955, June 2002
Lansoprazole for the Prevention of Recurrences of Ulcer Complications from Long-Term Low- Dose Aspirin Use
The New England Journal of Medicine, 346 : 26, 2033-2038, June 2002
