What clinical and molecular markers improve the screening, prevention, detection, diagnosis, prognosis and treatment of infectious diseases and sepsis in the emergency department?
What are the underlying mechanisms of disease influencing the presence of these markers?
How could these markers guide the development of novel diagnostics, prognostics, vaccines and treatments?
Can be adapted in scope for Honours, Masters or PhD
Infectious Disease is the most common presentation in emergency departments worldwide and sepsis is the leading cause of hospital death. The broad range of pathogens coupled with an equally broad range of immunological and inflammatory responses render this one of the most complicated fields of disease in man. Our research team aims to obtain an in-depth understanding of the immune environment in infectious diseases and sepsis and to establish a new combination of multiple immunotherapies.
Using well-established, preclinical models, the student will investigate therapeutic efficacy and mechanisms of new anti-sepsis therapies.
In the proposed project, the student will learn the following research techniques:
In collaboration with clinical laboratories, we will also investigate how immune cells are impaired in the infectious diseases microenvironment.
Professor Timothy Rainer
Tel: 3917 6846
Professor Aimin Xu
Tel: 3917 9754