Research Areas

AIDS Institute

http://www.med.hku.hk/aidsinst

Major Research Areas

• HIV/AIDS mucosal vaccine and pathogenesis.
• Targeting dendritic cells − PD1-based vaccine for the functional cure of HIV infection.
• Engineering of recombinant neutralising monoclonal antibodies against HIV/AIDS.
• Understanding the evolution of the HIV epidemic in Hong Kong and in the region.
• Elimination and cure of tumour by active vaccination and oncolytic virus.

• Molecular mechanism of innate immunity.
• Investigation on host-pathogen interaction, specifically the host antiviral responses.
• Molecular mechanism of the host defence signalling pathway in influenza A virus (IAV) and HIV infection.

• HIV immune evasion by suppressing host B cell and T cell response.
• Vaccine design and innate immune response in shaping potent T cell immunity.
• Immunopathology of SARS-CoV infection.