Research Areas

Department of Orthopaedics and Traumatology

How does bone and joint degeneration develop and can this be controlled to reduce disability?

Can biomaterials help regenerate tissue and organs in humans?

Major Research Areas

Orthopaedic biomechanics:
Biomechanics of bone and joint; biomechanical analysis of lumbar interbody fusion, new artificial intervertebral disc design and shape memory alloy in spine surgery. Finger fracture fixations, flexor tendon injuries and sports injuries biomechanics; biomechanics of total hip replacement; fixation implant design and development; biomechanical evaluation of biomaterials; cell biomechanics and micro/ nano-biomechanics.

Molecular biology and cellular physiology:
Animal models of musculoskeletal disorders; experimental scoliosis; genetics of degenerative disc disease and osteoarthritis; gene functions in articular and intervertebral joints; proteoglycan metabolism in skeletal tissues. Bone healing and fracture repair; genetic profiles of bone tumours and cell-biomaterial interfacial biology.

Regenerative medicine:
Developing disease-modifying agents for treating joint degeneration; programming stem cells or progenitors for joint regeneration; role of fibrosis and its control in tissue repair and mesenchymal stem cell-based therapies.

Orthopaedic biomaterials and musculoskeletal tissue engineering:
Biomaterials for clinical applications; bio-mimetic and 3D bio-printing; design of new orthopaedic implants; novel bone substitutes and micro- or nano-biomaterials; bioactive bone cement development.

Clinical neurophysiology and neural engineering in orthopaedics:
Neurophysiological detection, neuroimage, and neurorehabilitation in orthopaedics and spinal disorder; bioelectrical engineering and biomedical devices in orthopaedics.

Clinical, translational, and evidence-based orthopaedics:
Large-scale population-based and epidemiological studies; risk factor assessment; novel imaging; biomarker hunting; "omics" modelling and analyses; data capturing and complex statistics; personalised orthopaedics; clinical patient and surgeon outcome studies.

Departmental Postgraduate Admission Advisor

Professor W.W. Lu
Tel: 3917 9593
Fax: 2818 5210
Email: wwlu@hku.hk / rmcyuen@hku.hk