Research Areas

Department of Ophthalmology

How do we prevent blindness?

Major Research Areas

  • Diabetic retinopathy screening.
  • Improving outcome of glaucoma interventions:
    • Augmentation and modification of trabeculectomy
    • Minimally invasive glaucoma surgeries
    • Effect of long-term glaucoma medications on subsequent glaucoma surgery
  • Cataract surgery:
    • Patient experience
    • Outcome measurements and improvements

Contact Person(s)

Dr J.C.H. Chan
Tel: 2518 1430 / 3962 1405
Email: jonochan@hku.hk

Oculoplastic and reconstructive surgery:

  • Thyroid eye disease − impact, complications and therapeutics.
  • Orbital inflammatory disorders.
  • Treatment of eyelid disorders.

Contact Person(s)

Dr J.J.C. Cheung
Tel: 2518 1430 / 3962 1405
Email: janicejc@hku.hk

Neuroprotection and regeneration in models of retinal neurodegeneration:

  • Trans-scleral electrical stimulation in traumatic optic neuropathy, retinal ischaemia reperfusion injury, and chronic glaucoma models in rats/rabbits.
  • Immune modulatory effects of the traditional Chinese medicine Lycium barbarum in Alzheimer's disease-related vision loss.
  • Mesenchymal stem cell-mediated rescue in mitochondrial dysfunction-related retinal ganglion cell degeneration in glaucoma models in rats/rabbits.
  • Photobiomodulation of retinal ganglion cell survival in rabbit retinal ischaemia reperfusion injury.
  • Continuous monitoring of electroretinogram using a wireless apparatus.

Contact Person(s)

Dr C.K. Chiu
Tel: 2831 5356
Email: datwai@hku.hk

Glaucoma:

  • Prevention of glaucoma progression with new treatment modalities and lifestyle modification.
  • Collagen crosslinking − its clinical application in glaucoma-related diseases and others.
  • Enhancement of disease detection and monitoring.

Myopia control

Contact Person(s)

Dr B.N.K. Choy
Tel: 2518 1430 / 3962 1405
Email: bnkchoy@hku.hk

Glaucoma:

  • Treatment of acute and chronic angle-closure glaucoma.
  • Risk factors and neuroprotection in normal-tension glaucoma.

Contact Person(s)

Professor J.S.M. Lai
Tel: 2518 1430 / 3962 1413
Email: laism@hku.hk

Surgical and medical retina:

  • Age-related macular degeneration, diabetic retinopathy, retinal vascular disease.
  • Paediatric retinal diseases.
  • Retinopathy of prematurity.
  • Medical education.

Contact Person(s)

Professor W.C. Lam
Tel: 2518 1430 / 3962 1405
Email: waichlam@hku.hk

Protecting eye and brain:

  • Protecting the developing retina − ocular angiogenesis, retinopathy of prematurity, oxygen-induced retinopathy.
  • Protecting the ageing retina − retinal ischaemia/reperfusion injury, diabetic retinopathy.
  • Protecting the brain − cerebral ischaemia/reperfusion injury, stroke.
  • Bioengineering − cell-based and optogenetics-controlled drug delivery.
  • Development of novel molecular and cellular therapeutic approaches for ocular and cerebral diseases.

Contact Person(s)

Dr A.C.Y. Lo
Tel: 2831 5363
Email: amylo@hku.hk

Anterior segment:

  • Epidemiology and novel treatment methods in dry eye disease.
  • In-vitro modelling of dry eye disease.
  • Pathophysiology and treatment of corneal neuropathy.
  • Treatment of sight-threatening ocular surface disease.

Retinal neuroprotection:

  • Transcorneal electrical stimulation as a neuroprotective strategy in retinal disease.
  • In-vitro modelling of the effect of retinal electrical stimulation.

Contact Person(s)

Dr K.C. Shih
Tel: 2518 1430 / 3962 1405
Email: kcshih@hku.hk

Glaucoma and anterior segment diseases:

  • Minimally invasive glaucoma surgeries.
  • Novel glaucoma treatment modalities.
  • Neuroprotection for glaucoma.
  • OCT imaging analysis with artificial intelligence.

Ophthalmic translational research:

  • Ophthalmic drug delivery systems.
  • Retinal imaging for neurodegenerative diseases.

Contact Person(s)

Dr J.Y.K. Chan
Tel: 2831 5361 / 3962 1405
Email: jchanyk@hku.hk

Protecting eye and brain:

  • Tissue engineering: All-aqueous immiscible liquid-liquid system as platforms to form cellular structures for potential transplantation purposes in the eye.
  • Building in vitro physiologically representative models: Eye-on-a-chip microfluidic platforms.
  • Intravitreal drug delivery: Engineering systems for encapsulation of ophthalmic drugs.
  • Development and modification of ophthalmic medical devices: Intraoperative tools, endotamponades and micro-surgical devices.

Contact Person(s)

Dr J.K.W. Wong
Tel: 2518 1430 / 3962 1405
Email: jwongkw@hku.hk

Chairman of Departmental Research Postgraduate Committee

Dr A.C.Y. Lo
Tel: 2831 5363
Email: amylo@hku.hk