Programme(s) to which this project applies: |
☑ MPhil/PhD | ☑ MRes[Med] | ☑ URIS |
Microbiota-gut-brain axis has been an emerging field and revolutionized study in pathology, diagnosis and treatment of neurological disorders. Crosstalk between gut microbiota and brain can be accomplished via immune system. In this study, lipopolysaccharide (LPS) will be used to induce systemic inflammation and neuroinflammation. Our hypothesis is that gut microbiota is an important mediator between the immune system and the central nervous system; and dietary intervention by selected prebiotics helps alleviating both systemic and neural inflammatory responses. This study investigates the link between gut microbiota, systemic and neural inflammation and identifying the metabolites involved in manipulating the immune network.
Professor RCC Chang, School of Biomedical Sciences
Professor Chang’s research interest is on four directions.
He has published over 170 peer-reviewed papers, 15 book chapters and edited 5 books in these areas. His h-index is 47 by Scopus. He is also listed as top 1% scholar since 2018.
Selected Publications (* = corresponding author)
Research Grants
Research in this laboratory is supported by GRF, HMRF, ITC, RGC-NSFC, BrightFocus Foundation.
Community Services
Professor Chang is the Chief Editor for American Journal of Alzheimer’s Disease and Other Dementias, Senior Editor/Asia Chief Editor for Journal of Neuroimmune Pharmacology, Associate handling Editor for Frontiers in Neurology, Frontiers in Neurosciences and Frontiers in Psychiatry. He is in the Scientific Advisory Board of International AD/PD Symposium, and Scientific Review Committee in Alzheimer Association. He is the member of editorial board of more than 20 different journals, and grant reviewer for different grant agencies/Foundations for different countries. He is the reviewer and speaker to make decision for the final round of grant proposal for Alzheimer Association, USA. Apart from Scientific community, Professor Chang has obtain Knowledge Exchange Fund to promote neuroscience and biotechnology education in high school.
Biography
HKU Scholars Hub
Laboratory Facebook
ResearchGate
rccchang@hku.hk
For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description. Interested candidates are advised to enclose with your email:
Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to rpgmed@hku.hk.
HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.
HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.
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