To investigate and develop novel therapeutic approaches for the treatment of malignant glioma based on translational in vitro and in vivo laboratory experiments
Chemotherapy drug resistance
The role of innate immune response
Tumour metabolic functions and cell death pathways
Recently, we found that pharmacological inhibition of serine synthesis could enhance temozolomide efficacy in glioblastoma, and that the expression level of the chaperone protein, P4HB, could predict treatment response and clinical prognosis.
To investigate and develop novel therapeutic approaches for the treatment of intracerebral haemorrhage based on translational in vitro and in vivo laboratory experiments
Pathophysiology of demyelination and remyelination following haemorrhagic stroke
The role of innate immune response in haematoma resorption
Neuroprotective measures to improve functional outcome
We recently found that vitamin D supplementation could significantly improve functional outcome following intracerebral haemorrhages by enhancing phagocytosis of red blood cells; vitamin D deficiency, on the other hand, was associated with poorer outcome.
Information on selected projects or research areas: Interested candidates are advised to email the relevant supervisors. Please enclose with your email: (i) your CV, (ii) a brief description of your research interest and experience, and (iii) two reference letters (reference letters not required for HKUMed UG students seeking MRes[Med] or URIS projects)
Research studies enquiries specific to the Department/School’s research should be directed to the Departmental Research Postgraduate Advisor: Professor K Man (firstname.lastname@example.org)
Information on the research programme, funding support and admission requirements could be found on the RPg Admissions website.