Research Area 1: Neurobiology of Retinal Ganglion Cells for Optic Nerve Regeneration and Neuroprotection
- Metabolism of retinal ganglion cells
- Single-cell transcriptomics
- Roles of non-coding RNA in axon regeneration
- In vivo retinal ganglion cell imaging
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Research Area 2: Advanced Ophthalmic Diagnostics
- Wide-field high speed optical coherence tomography
- Retinal nerve fiber layer optical texture analysis
- Virtual reality assessment of visual disability
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Research Area 3: Clinical Trials for Prevention of Glaucoma Blindness
- Nicotinamide riboside for neuroprotection in glaucoma
- Metformin for neuroprotection in glaucoma
- Novel surgical devices for intraocular pressure reduction
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Research Area 4: Ocular Surface Diseases and Corneal Wound Healing
- Epidemiology and advances in management of dry eye diseases
- The impact of the gut microbiome on ocular surface disease health
- Improving corneal wound healing through novel topical therapeutics
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Research Area 5: Deep-Learning Systems in Ophthalmology
- The use of deep learning systems to enhance diagnosis of cornea ectasia in Asians
- AI-assisted triage and management of patients with visual loss
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Research Area 6: Protecting the Eye and the Brain
- Protecting the developing retina − ocular angiogenesis, retinopathy of prematurity, oxygen-induced retinopathy
- Protecting the aging retina − retinal ischaemia/reperfusion injury, diabetic retinopathy, corneal nerve analyses for diabetic neuropathy
- Protecting the brain − cerebral ischaemia/reperfusion injury, stroke
- Bioengineering − cell-based controlled drug delivery
- Development of novel molecular and cellular therapeutic approaches for ocular and cerebral diseases
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Research Area 7: Glaucoma
- Prevention of glaucoma progression with new treatment modalities and lifestyle modification
- Collagen crosslinking − its clinical application in glaucoma-related diseases and others
- Enhancement of disease detection and monitoring
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Research Area 8: Myopia Control
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Research Area 9: Improving Outcome of Glaucoma Interventions
- Augmentation and modification of trabeculectomy
- Minimally invasive glaucoma surgeries
- Effect of long-term glaucoma medications on subsequent glaucoma surgery
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Research Area 10: Cataract Surgery
- Patient experience
- Output measurements and improvements
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Research Area 11: Biomedical Engineering
- Building in vitro physiologically representative models: Eye-on-a-chip microfluidic platforms for glaucoma-related and corneal scarring-related studies
- Contact lens-based devices for theranostics applications
- Microfluidic-based diagnostic tools for small volume samples
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Research Area 12: Ocular Surface Oncology
- Epidemiology of ocular surface tumours
- Role of micro-organisms in pathogenesis of ocular surface tumours
- Evidence based practice in management of ocular surface tumours
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Research Area 13: Ophthalmic Microbiology
- Antimicrobial susceptibility of ophthalmic pathogens
- Microbiology of the ocular surface
- Antimicrobial stewardship in ophthalmology
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Research Area 14: Diabetic Retinopathy Screening
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Find Out More
Information on selected projects or research areas: Interested candidates are advised to email the relevant supervisors. Please enclose with your email: (i) your CV, (ii) a brief description of your research interest and experience, and (iii) two reference letters (reference letters not required for HKUMed UG students seeking MRes[Med] or URIS projects)
Research studies enquiries specific to the Department/School’s research should be directed to the Departmental Research Postgraduate Advisor: Dr ACY Lo ( amylo@hku.hk)
Information on the research programme, funding support and admission requirements could be found on the RPg Admissions website.
General admission enquiries should be directed to rpgmed@hku.hk.
Meet Our Students
JIA Shuo
Place of Origin: China
Progress: PhD Year 3
Supervisor: Dr JCH Chan
全球眼角膜供給極為短缺，無法滿足角膜移植的需求。三年前，3D打印技術打印出世界上首個人工角膜；生物打印技術的推進，為行業帶來積極訊號。賈碩說，「但它存在很多不足，若想運用於移植，還需假以時日。」
「人工角膜需要實現更高的精細度，我們現在研究的，便是對生物打印技術進行革新，重建功能化的眼角膜。」
賈碩所研究的3D打印角膜技術，已經進入動物實驗環節，測試眼角膜在生物體內的相容性。她坦言目前的技術尚未達到理想化的狀態。在導師的鼓勵下，她在日常實驗中摸索門徑，探求新的技術，填補目前的技術空缺。去年，賈碩被導師推薦至中國科學院、天津大學等地進行調研和學習器官打印。希望能完成心目中的遠大計劃——解決眼庫角膜短缺的問題。
June 2021
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