Department of Ophthalmology


Research Questions

  • How do we prevent blindness?
Researchers at Department of Ophthalmology

1. Diabetic Retinopathy Screening

  • Improving outcome of glaucoma interventions:
    • Augmentation and modification of trabeculectomy
    • Minimally invasive glaucoma surgeries
    • Effect of long-term glaucoma medications on subsequent glaucoma surgery
  • Cataract surgery:
    • Patient experience
    • Outcome measurements and improvements 

2. Improving Outcome of Glaucoma Interventions

  • Augmentation and modification of trabeculectomy
  • Minimally invasive glaucoma surgeries
  • Effect of long-term glaucoma medications on subsequent glaucoma surgery

3. Cataract Surgery

  • Patient experience
  • Output measurements and improvements
Supervisor(s)

Dr JCH Chan

 

4. Biomedical Engineering

  • Building in vitro physiologically representative models: Eye-on-a-chip microfluidic platforms for glaucoma-related and corneal scarring-related studies
  • Contact lens-based devices for theranostics applications
  • Microfluidic-based diagnostic tools for small volume samples
Supervisor(s)

Dr JYK Chan

 

5. Glaucoma

  • Prevention of glaucoma progression with new treatment modalities and lifestyle modification
  • Collagen crosslinking − its clinical application in glaucoma-related diseases and others
  • Enhancement of disease detection and monitoring
  • Myopia control
Supervisor(s)

Dr BNK Choy

 

6. Surgical and Medical Retina

  • Age-related macular degeneration, diabetic retinopathy, retinal vascular disease
  • Paediatric retinal diseases
  • Retinopathy of prematurity
  • Medical education

7. Paediatric Retinal Diseases

  • Hereditary retinal diseases: investigation, and treatment (including gene therapy)
  • Paediatric retinal diseases
  • Retinopathy of prematurity

8. Myopia Prevention

  • Collaborative study investigating the effectiveness of combination therapy
  • Medical Education
Supervisor(s)

Professor WC Lam

 

7. Ocular Surface Oncology

  • Epidemiology of ocular surface tumours
  • Role of micro-organisms in pathogenesis of ocular surface tumours
  • Evidence based practice in management of ocular surface tumours

8. Ophthalmic Microbiology

  • Antimicrobial susceptibility of ophthalmic pathogens
  • Microbiology of the ocular surface
  • Antimicrobial stewardship in ophthalmology
Supervisor(s)

Dr A Lee

 

9. Protecting the Eye and the Brain

  • Protecting the developing retina − ocular angiogenesis, retinopathy of prematurity, oxygen-induced retinopathy
  • Protecting the ageing retina − retinal ischaemia/reperfusion injury, diabetic retinopathy
  • Protecting the brain − cerebral ischaemia/reperfusion injury, stroke
  • Bioengineering − cell-based and optogenetics-controlled drug delivery
  • Development of novel molecular and cellular therapeutic approaches for ocular and cerebral diseases
Supervisor(s)

Dr ACY Lo

 

10. Anterior Segment

  • Epidemiology and novel treatment methods in dry eye disease
  • In-vitro modelling of dry eye disease
  • Pathophysiology and treatment of corneal neuropathy
  • Treatment of sight-threatening ocular surface disease

11. Retinal Neuroprotection

  • Transcorneal electrical stimulation as a neuroprotective strategy in retinal disease
  • In-vitro modelling of the effect of retinal electrical stimulation
Supervisor(s)

Dr KC Shih

 

12. Clinical Researches in Glaucoma

  • Glaucoma assessments and treatments
  • Minimally invasive glaucoma surgeries

13. Translational Ophthalmic Researches

  • Novel glaucoma treatment modalities
  • Intraocular drug delivery systems
  • Artificial intelligence on ophthalmic imaging
  • Ocular imaging technologies
Supervisor(s)

Dr JKW Wong

For more information or to express interest to join the research areas, please email the supervisor or the specified contact point in the description. Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Research postgraduate studies enquiries specific to the department/school’s research should be directed to the Chairman of the Departmental Research Postgraduate Committee:

Dr ACY Lo
amylo@hku.hk

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website.

General admission enquiries should be directed to rpgmed@hku.hk.

Our Students

JIA Shuo

Place of Origin: China
Progress: PhD Year 3
Supervisor: Dr JCH Chan

全球眼角膜供給極為短缺,無法滿足角膜移植的需求。三年前,3D打印技術打印出世界上首個人工角膜;生物打印技術的推進,為行業帶來積極訊號。賈碩說,「但它存在很多不足,若想運用於移植,還需假以時日。」

「人工角膜需要實現更高的精細度,我們現在研究的,便是對生物打印技術進行革新,重建功能化的眼角膜。」

賈碩所研究的3D打印角膜技術,已經進入動物實驗環節,測試眼角膜在生物體內的相容性。她坦言目前的技術尚未達到理想化的狀態。在導師的鼓勵下,她在日常實驗中摸索門徑,探求新的技術,填補目前的技術空缺。去年,賈碩被導師推薦至中國科學院、天津大學等地進行調研和學習器官打印。希望能完成心目中的遠大計劃——解決眼庫角膜短缺的問題。

June 2021