PHAR6200 Current Development in Pharmacology and Pharmaceutics
To provide a broad overview of the current trends of drug development, pharmacogenomics and the challenges in drug delivery including biologics and nucleic acids. Novel drug delivery systems, the process of clinical trials as well as the development of nanomedicine and the potential nanotoxicity will be discussed.
To outline the pathophysiology of the cardiac and respiratory systems and to discuss with students the current and potential therapeutic strategies for the management of cardiac and respiratory diseases.
To introduce how different regulatory systems coordinate together the maintenance of vascular tone and vascular integrity, and the rationale behind the current and prospective drug treatments for vascular diseases and vascular complications of diabetes, hypertension and dyslipidemia.
Advanced drug delivery and drug development
Current trends in drug delivery and drug development
Nanotechnology and nanomedicines
Novel drug delivery systems
Stimulitriggered drug delivery and targeted drug delivery
Drugs for the treatment of heart and lung diseases
Current therapeutic approaches for several cardiac and respiratory diseases
General physiology and functions of the cardiac and respiratory systems
Pathologies of cardiac and respiratory systems
Research and development of new treatments for heart and lung diseases
Vascular biology and therapeutics
Current knowledge and advanced research findings on the neuronal, hormonal and local control of the vascular system under normal and pathological conditions
Functions of the systemic and pulmonary vasculature
Regulatory mechanisms for the maintenance of vascular integrity and tone
Management of vascular disorders and the complications of dyslipidemia, hypertension and diabetes, in particular thrombosis and atherosclerosis
On completion of these courses, students will be able to:
explain the basic principle of drug delivery and dosage form design.
describe the important of pharmacogenomics and clinical trials process.
identify the barriers to drug delivery, compare different drug delivery systems and discuss potentials and problems of nanomedicines.
describe the regulatory systems of the heart and the lungs.
identify the risk factors for heart and lung diseases and discuss the therapeutic strategies.
explain the mechanisms of actions of current and prospective drugs and assess their benefits and risks.
critically analyse the clinical evidence and assess the claims released by the pharmaceutical industries.
explain the importance of the regulation of the vascular system and integrate the different regulatory systems for the maintenance of vascular functions and integrity.
explain the underlying mechanisms leading to various pathologies of the vascular system.
critically appraise experimental methodologies and findings in vascular biology research.
identify the rationale of current and prospective pharmacological treatments for vascular diseases and vascular complications of diabetes, hypertension and dyslipidemia.
Mode of teaching: Lectures, Essay writing, Literature review, Presentations and Group Discussion
Assessment: In-course assessment and Final examination
Dr SWS Leung
Tel no.: 3917 9252
Fax no.: 2817 0859