Research

Professor GCF Chan, Department of Paediatrics and Adolescent Medicine

• Outstanding Asian Pediatrician Award by Asia Pacific Pediatric Association (2018)
  

Professor KSE Cheah, School of Biomedical Sciences 

• Fellow of the World Academy of Sciences for the Advancement of Sciences in Developing Countries (2013)

Professor EYH Chen, Department of Psychiatry

• Richard J Wyatt Award from the International Early Psychosis Association (2014)

Professor SWK Cheng, Department of Surgery

• Honorary Fellow of the American Surgical Association 

Professor KMC Cheung, Department of Orthopaedics and Traumatology

• Foundation of Orthopedics and Complex Spine Humanitarian Award (FOCOS) (2015)
• Honorary Fellowship of the Asia Pacific Orthopaedics Association (2018)

Professor R Bruzzone, School of Public Health

• Insignia of Knight of the Order of Merit of Italian Republic by Italian Consulate (2018)

Professor BJ Cowling and Dr P Wu, School of Public Health

• Charles C Shepard Science Awards of Center for Disease Control and Prevention, USA (2018)

Professor R Fielding, School of Public Health

• International Psycho-Oncology Society Arthur M Sutherland Award by the 2018 World Congress of Psycho-Oncology (2018)

Professor K Fukuda, School of Public Health

• Fellowship by Faculty of Public Health of the Royal Colleges of Physicians, UK (2018)

Professor Y Guan, School of Public Health

• World’s Most Influential Scientific Minds awarded by Thomas Reuters (2015)
• Fellowship by Faculty of Public Health of the Royal Colleges of Physicians, UK (2017)

Dr Y Hu, Department of Orthopaedics and Traumatology

• Silver Medal by International Exhibition of Inventions of Geneva for the project “Soft Robotic Glove for Rehabilitation” (2019)

Professor MSM Ip, Department of Medicine

• Asian Pacific Society of Respirology Medal by Asian Pacific Society of Respirology (2013)

Professor CC Lin, School of Nursing

• International Nurse Researcher Hall of Fame of the Sigma Theta Tau International Honor Society of Nursing (2020)

Professor YL Kwong and Professor CR Kumana, Department of Medicine

• Gold Medal by the 46th International Exhibition of Inventions of Geneva for the project “Arsenol®: The First Oral Formulation of Arsenic Trioxide” (2018)

Professor CL Lai, Department of Medicine

• Fellow of American Association for the Study of Liver Diseases (AASLD) 2014

Professor CLK Lam, Department of Family Medicine and Primary Care

• Distinguished Research Making Family Shine Award and Best Contribution to Family Medicine Award in the WONCA World Conference (2018)

Professor CS Lau, Department of Medicine

• Fellow of Academy of Medicine, Malaysia
• Fellow of Academy of Medicine, Singapore
• Foreign Member of the Academia Europaea

Professor YL Lau, Department of Paediatrics and Adolescent Medicine 

• Outstanding Asian Pediatrician Award by Asia Pacific Pediatric Association (2018)

Professor AWM Lee, Department of Clinical Oncology

• Honorary Fellow of American College of Radiology (2019) 

Professor FKL Leung, Department of Orthopaedics and Traumatology

• Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) Research Award – Clinical Science (2017)

Professor GM Leung, LKS Faculty of Medicine and School of Public Health 

• Elected Member of US National Academy of Medicine (2018)

Professor WW Lu, Professor FKL Leung, Dr SA Kulper and Dr CXS Fang, Department of Orthopaedics and Traumatology

• Silver medal by the 46th International Exhibition of Inventions of Geneva for the project “Bone Screw – Anti-Penetration Bone Implant Device And Method” (2018)

Professor HYS Ngan, Department of Obstetrics and Gynaecology

• International Federation of Gynecology and Obstetrics Award (2018) 

Professor JSM Peiris, School of Public Health 

• Named one of the 10 “Science Stars of East Asia” by leading medical Journal Nature (2018)
• Elected Foreign Associate of US National Academy of Sciences (2017) 
• Fellow of American Academy of Microbiology (2016)
• Fellow of the American Society for Microbiology (2016)
• Officier de la Legion d’Honneur, France (2017)
• World’s Most Influential Scientific Minds awarded by Thomas Reuters (2015)
• Knight of the Légion d’Honneur, France (2007)
• Fellow of the Royal Society, London (2006)

Professor LLM Poon, School of Public Health

• World’s Most Influential Scientific Minds awarded by Thomas Reuters (2015)
• Fellowship by Faculty of Public Health of the Royal Colleges of Physicians, UK (2017)

Professor PKH Tam, Department of Surgery 

• Denis Browne Gold Medal by the British Association of Pediatric Surgeons (2017)

Professor ICK Wong, Department of Pharmacology and Pharmacy

• Fellow of Royal Pharmaceutical Society, UK (2013)

Professor KY Yuen, Department of Microbiology

• Fellow of American Academy of Microbiology (2019)
• Fellow of the American Society for Microbiology (2019)
• Named 1 of the 10 Science Stars of East Asia featured in Nature (2018)
• World’s Most Influential Scientific Minds awarded by Thomas Reuters (2015)

Professor A Xu, Departments of Medicine and Pharmacology and Pharmacy

• Gold Medal by the International Exhibition of Inventions of Geneva for the project “Methods and Compositions for Use of Neutrophil Elastase and Proteinase 3 as Diagnostic Biomarkers” (2019)

Dr ACY Chan, Department of Surgery 

• Dr Abdol and Mrs Joan Islami International Guest Scholar awarded by the American College Surgeons (2017/18)

Dr JPY Cheung, Department of Orthopaedics and Traumatology 

• Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) Research Award – Young Investigator Award (2017)

Dr JYW Chan, Department of Surgery

• Carlos Pellegrini Fellow of the American College of Surgeons (2017/18)

Dr RYC Kao, Department of Microbiology

• First Prize of the Innovative Academy Award by the Geneva International Conference for Prevention and Infection Control (2017)

Dr PPW Lee, Department of Paediatrics and Adolescent Medicine  

• Fellow of the Higher Education Academy, UK (2018)

Dr WHC Li, School of Nursing 

• Fellow of the American Academy of Nursing (2019)

Dr KWM Pang, School of Nursing

• Fellow of the American Academy of Nursing (2019)
• Pi lota Chapter Scholarship 2017/18 by the Sigma Theta Tau International, Honor Society of Nursing (2018)

Dr WWK Seto, Department of Medicine 

• Emerging Leader Lectureship at the Asian Pacific Digestive Week awarded by the Journal of Gastroenterology and Hepatology Foundation (2018)

Dr KC Shih, Department of Ophthalmology

• Asia Pacific Academy of Ophthalmology Achievement Award (2018)

Dr IYH Wong, Department of Ophthalmology

• Asia Pacific Academy of Ophthalmology Achievement Award (2018)

Dr J Yang, School of Biomedical Sciences

• Fellow of the Higher Education Academy, UK (2018)

Professors HL Chen and KY Yuen, Dr KKW To, Department of Microbiology; Professor Y Guan, Drs TY Lam, and HC Zhu, School of Public Health

• State Science and Technology Progress Award (Special Class), 2017
  國家科學技術進步獎特等獎 2017 

Professor ZW Chen, Department of Microbiology

• “China New Development Award” by Springer Nature 2019
  施普林格·自然「中國新發展獎」2019

Professor SWK Cheng, Department of Surgery

• Chairman of the Guangdong-Hong Kong-Macau Greater Bay Area Vascular Surgery Alliance
  粵港澳大灣區心血管手術聯盟主席

Professor JCS Chim, Department of Medicine

• State Scientific and Technological Progress Award (Second Class), China, 2009
  國家科學技術進步獎二等獎 2009 

Professor ST Fan, Professor CM Lo, Dr CL Liu and Dr SC Chan, Department of Surgery

• State Science and Technology Progress Award (First Class), 2005
  國家科學技術進步獎二等獎 2005 

Professor ST Fan, Department of Surgery

• Academician, Chinese Academy of Engineering (Medicine and Health), 2005
  中國工程院院士（醫藥衞生學部）2005

Professor XY Guan, Department of Clinical Oncology

• State Scientific and Technological Progress Award (First Class), China, 2012
  國家科技進步獎一等獎2012
• National Prize for Natural Sciences of China (Second Class), 2010
  國家自然科學獎二等獎 2010
• Natural Science Prize of Shanghai (First Class), 2009
  上海市自然科學獎二等獎 2009
• Science and Technology Award of Higher Education of China (First Class), Ministry of Education, China, 2007
  教育部高等學校科學技術獎一等獎 2007

Professor Y Guan, School of Public Health

• Prize for Progress in Science and Technology, Ho Leung Ho Lee Foundation, China, 2013
  何梁何利基金科學與技術進步獎 2013
• First Class Award in Research Achievements (Science and Technology), Ministry of Education, China, 2009
  教育部高等學校科學研究優秀成果獎（科學技術）一等獎 2009

Professor DY Jin, School of Biomedical Sciences 

• State Natural Science Award (Second Class), 2001
  國家自然科學獎二等獎 2001

Professor AWM Lee, Department of Clinical Oncology

• Science and Technology First Class Award by Fujian Provincial People’s Government, 2018
  福建省人民政府頒發福建省科學技術獎一等獎 2018
• “Good Clinician in Shenzhen” awarded by Shenzhen Municipal Health Commission 2018
  深圳市衞生健康委員會頒發「深圳好醫生」殊榮 2018

Professor CM Lo, Department of Surgery

• First Class Award in Research Achievements (Science and Technology), Ministry of Education, China, 2013
  教育部高等學校科學研究優秀成果獎（科學技術）一等獎 2013

Professor WW Lu, Department of Orthopaedics and Traumatology

• • State Science and Technology Progress Award (Second Class), 2017
  國家科學技術進步獎二等獎 2017 

Professor EHY Ng, Department of Obstetrics and Gynaecology

• State Science and Technology Progress Award (Second Class), 2014
  國家科學技術進步獎二等獎 2014
• Second Class Award in Research Achievements (Science and Technology), Ministry of Education, China, 2010
  教育部高等學校科學研究優秀成果獎（科學技術）二等獎 2010

Professor KF So, School of Biomedical Sciences 

• Academician, Chinese Academy of Sciences, 1999
  中國科學院院士 1999
• State Natural Science Award (Second Class), 1995
  國家自然科學獎二等獎1995

Professor WI Wei, Department of Surgery 

• State Science and Technology Progress Award (Second Class), 2012
  國家科學技術進步獎二等獎 2012 

Professor K Yeung, Department of Orthopaedics and Traumatology 

• Orthopaedics Youth Research Award 2nd prize by the Chinese Orthopaedic Association 2018
  中華醫學院骨科分會骨科基礎青年研究獎二等獎 2018

Professor KY Yuen, Department of Microbiology

• Academician, Chinese Academy of Engineering (Medicine and Health), 2007
  中國工程院院士（醫藥衞生學部）2007
• State Science and Technology Progress Award (Special Class), 2017
  國家科學技術進步獎特等獎 2017 

Professor Z Zhou, School of Biomedical Sciences 

• State Science and Technology Progress Award (Second Class), 2010
  國家科學技術進步獎二等獎 2010 

Dr Y Hu, Department of Orthopaedics and Traumatology

• State Scientific and Technological Progress Award (Second Class), China, 2020
  國家科技進步獎二等獎2020

Dr RYT Kao, Dr JFW Chan and Dr ML Yeung, Department of Microbiology

• State Scientific and Technological Progress Award (Second Class), China, 2020
  國家科技進步獎二等獎2020

Dr ZY Xia, Department of Anaesthesiology 

• President, Chinese Society of Translational Perioperative Medicine and Research (2017)
  中國圍手術期轉化醫學研究學會會長
• Chinese Society of Cardiothoracic and Vascular Anesthesiologists Award of Recognition (2018)
  中國心胸血管麻醉學會獎 2018

Dr H Zhu, School of Public Health

• Chinese Young Women in Science Award 2020 
  中國青年女科學家獎 2020

Professor CW Cheung, Department of Anaesthesiology

• President of the Hong Kong College of Anaesthesiologist (2017-19)
  

Professor BJ Cowling, School of Public Health

• Founding Member of the Hong Kong Young Academy of Sciences 2018
  

Professor ST Fan, Department of Surgery

• Founding member of Hong Kong Academy of Sciences (2015)

Professor IFN Hung, Department of Medicine

• Distinguished Young Fellow of the Hong Kong Academy of Medicine 2017

Professor WCS Lau, Department of Medicine

• President of the Hong Kong Academy of Medicine (2017 – present)
  

Professor CLK Lam, Department of Family Medicine and Primary Care

• Chairman, Advisory Committee on Primary Care Directory, Department of Health of the HKSAR Government (2017) 
  

Professor GKK Leung, Department of Surgery

• Vice President (Education & Examinations) of the Hong Kong Academy of Medicine (2017 – present)
  

Professor KDK Luk, Department of Orthopaedics and Traumatology

• Honorary Fellowship, Hong Kong College of Orthopaedic Surgeons (2018)

Professor K Man, Department of Surgery

• President, International Liver Transplantation Society (2017)
  

Professor HYS Ngan, Department of Obstetrics and Gynaecology

• Fellow of the Hong Kong College of Obstetricians and Gynaecologists 2019
  

Professor JSM Peiris, School of Public Health 

• Founding Member of the Hong Kong Academy of Sciences (2015)
  

Professor LLM Poon, School of Public Health

• Founding Member of the Hong Kong Young Academy of Sciences 2018
  

Professor GWK Tang, Department of Obstetrics and Gynaecology

• Honorary Fellow of Hong Kong Academy of Medicine
  

Professor RTT Young, Department of Medicine

• Honorary Fellow of Hong Kong Academy of Medicine
  

Professor KY Yuen, Department of Microbiology

• Founding Member of the Hong Kong Academy of Sciences (2015)
  

Dr PPW Lee, Department of Paediatrics and Adolescent Medicine  

• Distinguished Young Fellow of the Hong Kong Academy of Medicine (2019)
  

Dr SKY Ma, School of Biomedical Sciences

• Founding Member of the Hong Kong Young Academy of Sciences 2018
  

Dr MKT To, Department of Orthopaedics and Traumatology

• Hong Kong Humanity Award 2018 by Hong Kong Red Cross and Radio Television HK

Grand Bauhinia Medal (GBM) 大紫荊勳章

• Professor RTT Young, Department of Medicine (2018) 
  

Gold Bauhinia Star (GBS) 金紫荊星章

• Professor JCY Leong, Department of Orthopaedics & Traumatology (2019)
• Professor KY Yuen, Department of Microbiology (2018)
• Professors GM Leung, LKS Faculty of Medicine and School of Public Health (2012)
• Professor RTT Young, Department of Medicine (2012) 

Silver Bauhinia Star (SBS) 銀紫荊星章

• Professor RHS Liang, Department of Medicine (2015)
• Professor JSM Peiris, School of Public Health (2008)
• Professor Grace Tang, Department of Obstetrics and Gynaecology (2008)
• Professor ST Fan, Department of Surgery (2006)
• Professor KY Yuen, School of Public Health (2004)
• Professor John Wong, Department of Surgery (2002)

Bronze Bauhinia Star (BBS) 銅紫荊星章

• Professor CS Lau, Department of Medicine (2022)
• Professor CM Lo, Department of Surgery (2015)
• Professors TH Lam, School of Public Health (2012)

Medal of Honour (MH) 榮譽勳章

• Professor CLK Lam, Department of Family Medicine and Primary Care (2018)

Justice of the Peace (太平紳士)

• Professor CS Lau, Department of Medicine (2018)
• Professor GM Leung, LKS Faculty of Medicine (2015) 

Croucher Senior Medical Research Fellowships

• Professor SCW Tang, Department of Medicine (2019-20)
• Professor AYH Leung, Department of Medicine (2017-18)
• Professor PCY Woo, Department of Microbiology (2015-16)
• Professor US Khoo, Department of Pathology (2015-16)
• Professor ANY Cheung, Department of Pathology (2014-15)
• Professor IOL Ng, Department of Pathology (2013-14)
• Professor JM Nicholls, Department of Pathology (2009-10)
• Professor SY Leung, Department of Pathology (2007-08)
• Professor KY Yuen, Department of Microbiology (2006-07)
• Professor IOL Ng, Department of Pathology (2005-06)
• Professor JSM Peiris, School of Public Health (2005-06)
• Professor CM Lo, Department of Surgery (2004-05)
• Professor ST Fan, Department of Surgery (1998-99)

Croucher Senior Research Fellowships

• Professor LLM Poon, School of Public Health (2017-18)
• Professor A Xu, Departments of Medicine and Pharmacology & Pharmacy (2016-17)
• Professor Z Zhou, School of Biomedical Sciences (2015-16)
• Professor B Cowling, School of Public Health (2015-16)
• Professor DY Jin, School of Biomedical Sciences (2014-15)
• Professor D Chan, School of Biomedical Sciences (2014-15)
• Professor LW Lu, Department of Pathology (2012-13)
• Professor KSE Cheah, School of Biomedical Sciences (2000-01)

Croucher Innovation Awards

• Dr CCL Wong, Department of Pathology (2017)
• Dr SKY Ma, School of Biomedical Sciences (2014)

See the complete list of HKU Scholars in the Top 1% for the past years

School of Biomedical Sciences

• Professor GSW Tsao
• Dr RCC Chang

School of Chinese Medicine

• Professor Y Feng
• Professor JG Shen

School of Nursing

• Dr DYT Fong

School of Public Health

• Professor BJ Cowling
• Professor Y Guan
• Professor TH Lam
• Professor GM Leung
• Professor JSM Peiris
• Professor LLM Poon
• Professor JTK Wu
• Dr MCW Chan
• Dr DSY Ho
• Dr TTY Lam
• Dr CM Schooling
• Dr PMF Siu
• Dr LW Tian
• Dr P Wu
• Dr H Zhu

Department of Clinical Oncology

• Professor XY Guan
• Professor SFM Kong

Department of Medicine

• Professor IFN Hung
• Professor YL Kwong
• Professor CL Lai
• Professor KSL Lam
• Professor CW Siu
• Professor HF Tse
• Professor A Xu (joint appointment with Department of Pharmacology and Pharmacy)
• Professor RMF Yuen
• Dr WWK Seto

Department of Microbiology

• Professor H Chen
• Professor KY Yuen
• Dr JFW Chan
• Dr PL Ho
• Dr KKW To

Department of Orthopaedics and Traumatology

• Professor KWK Yeung

Department of Paediatrics and Adolescent Medicine

• Professor YL Lau

Department of Pathology

• Professor L Lu
• Professor TW Mak
• Professor IOL Ng
• Professor JM Nicholls

Department of Pharmacology and Pharmacy

• Professor Y Wang
• Professor ICK Wong
• Professor A Xu (joint appointment with Department of Medicine)

Department of Psychiatry

• Professor EYH Chen
• Professor PC Sham
• Dr SKW Chan
• Dr WC Chang
• Dr CLM Hui
• Dr EHM Lee

Department of Surgery

• Professor CM Lo

Research Output Prize/Awards

• University Research Output Prize (ROP)
• 2023
• “Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron”, Nature. 603(7902):693-699. doi: 10.1038/s41586-022-04442-5. Epub 2022 Jan 21. PMID: 35062016. 
  HKU Authors: HP Shuai, BJ Hu, Y Chai,  Terrence TT Yuen, X Huang, CM Yoon, H Liu, JL Shi, YC Liu, TRZ Zhu, JJ Zhang, YX Hou, YX Wang, L Lu, JP Cai, SF Yuan, Jasper FW Chan, J Zhou, Anna JX Zhang, J Hin, JD Huang, Kelvin KW To, KY Yuen..
• 2022
• “Clofazimine broadly inhibits coronaviruses including SARS-Co-2”, Nature, 2021, Vol.593, pp. 418-423 by Shuofeng Yuan, Xiangzhi Meng, Jasper Fuk-Woo Chan, Zi-Wei Ye, Chris Chun-Yiu Chan, Pok-Man Lai, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Andrew Chak-Yiu Lee, Chun-Kit Yuen, Jianli Cao, Ronghui Liang, Kaiming Tang, Li Sheng, Wan Xu, Chit-Ying Lau, Ko-Yung Sit, Wing-Kuk Au, Runming Wang, Kong-Hung Sze, Anna Jinxia Zhang, Hin Chu, Kin-Hang Kok, Ivan Fan-Ngai Hung, Ronald Adolphus Li, Honglin Chen, Hongzhe Sun, Dong-Yan Jin, Ren Sun, Kwok-Yung Yuen.
• 2021
• “A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster”, The Lancet, 2020, Vol. 395, Issue 10223, pp. 514-523 by Jasper Fuk-Woo Chan, Shuofeng Yuan, Kin-Hang Kok, Kelvin Kai-Wang To, Hin Chu, Jin Yang, Fanfan Xing, Jieling Liu, Cyril Chik-Yan Yip, Rosana Wing-Shan Poon, Hoi-Wah Tsoi, Simon Kam-Fai Lo, Kwok-Hung Chan, Vincent Kwok-Man Poon, Wan-Mui Chan, Jonathan Daniel Ip, Jian-Piao Cai, Vincent Chi-Chung Cheng, Honglin Chen, Christopher Kim-Ming Hui, Kwok-Yung Yuen*.
• 2020
• “Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank”, BMJ, 06 March 2019, Vol.364, by Shan Luo, Shiu Lun Au Yeung, Jie V Zhao, Stephen Burgess, C Mary Schooling*.
• 2019
• “A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening”, Cell Stem Cell, 2018, Vol. 23, Issue 6, pp. 882-897, by Helen HN Yan, Hoi Cheong Siu, Simon Law, Siu Lun Ho, Sarah SK Yue, Wai Yin Tsui, Dessy Chan, April S Chan, Stephanie Ma, Ka On Lam, Sina Bartfeld, Alice HY Man*, Bernard CH Lee*, Annie SY Chan, Jason WH Wong*, Priscilla SW Cheng*, Anthony KW Chan*, Jiangwen Zhang, Jue Shi, Xiaodan Fan, Dora LW Kwong*, Tak W Mak, Siu Tsan Yuen, Hans Clever, Suet Yi Leung*.
• 2018
• “The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity”, Cell Metabolism, September 2017, Vol. 26, Issue 3, pp. 493 – 508, by Zhe Huang*, Ling Zhong*, Jimmy TH Lee*, Jialiang Zhang*, Donghai Wu, Leiluo Geng*, Yu Wang*, Chi-Ming Wong*, Aimin Xu*.
• 2017
• “Fractional dosing of yellow fever vaccine to extend supply: a modelling study”, The Lancet, December 2016, Vol. 388, No. 10062, pp. 2904 – 2911 by Joseph T Wu*, Corey M Peak, Gabriel M Leung*, Marc Lipsitch.
• 2016
• “Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial”, The Lancet Infectious Diseases, February 2016 (published online on 8 November 2015), Vol. 16, Issue 2, pp. 209 – 218, by Ivan FN Hung*, Anna Jinxia Zhang*, Kelvin KW To*, Jasper FW Chan*, Patrick Li*, Tin-Lun Wong*, Ricky Zhang*, Tuen-Ching Chan*, Brian CY Chan*, Harrison H Wai*, Lok-Wun Chan*, Hugo PY Fong*, Raymond KC Hui*, Ka-Lun Kong*, Arthur CF Leung*, Abe HT Ngan*, Louise WK Tsang*, Alex PC Yeung*, Geo CN Yiu*, Wing Yung*, Johnson YN Lau*, Honglin Chen*, Kwok-Hung Chan*, Kwok-Yung Yuen*.
• 2015
• “Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study”, The Lancet, February 2014, Vol. 383, No. 9916, pp. 541 – 548, by Hongjie Yu, Joseph T Wu*, Benjamin J Cowling*, Qiaohong Liao, Vicky J Fang*, Sheng Zhou, Peng Wu*, Hang Zhou, Eric HY Lau*, Danhuai Guo, Michael Y Ni*, Zhibin Peng, Luzhao Feng, Hui Jiang, Huiming Luo, Qun Li, Zijian Feng, Yu Wang, Weizhong Yang, Gabriel M Leung*.
• Faculty Outstanding Research Output Awards
  • 2023
    • Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection. N Engl J Med. 387(21):1957-1968, Nov 24 2022. doi: 10.1056/NEJMoa2210027. Epub 2022 Nov 8. PMID: 36346079. HKU Authors: Richard MF Yuen.
    • Sequential transarterial chemoembolisation and stereotactic body radiotherapy followed by immunotherapy as conversion therapy for patients with locally advanced, unresectable hepatocellular carcinoma (START-FIT): a single-arm, phase 2 trial. Lancet Gastroenterology & Hepatology. 2023 Feb;8(2):169-178. doi: 10.1016/S2468-1253(22)00339-9. Epub 2022 Dec 15. PMID: 36529152. HKU Authors: CB Li, TC Lam, SK Chan, Aya El Helali, Spring FM Kong, Albert CY Chan, K Man, CM Lo, CL Chiang.
    • Cost-effectiveness of universal screening for chronic hepatitis B virus infection in China: an economic evaluation. Lancet Global Health. 10(2)2:E278-E287. doi: 10.1016/S2214-109X(21)00517-9. HKU Authors: Richard MF Yuen, WK Seto, William CW Wong.
    • Artesunate suppresses Th17 response via inhibiting IRF4-mediated glycolysis and ameliorates Sjog̈ren’s syndrome. Signal Transduction and Targeted Therapy. 7, 274. doi: 10.1038/s41392. HKU Authors: F Xiao, EY Huang, LW Lu.
    • Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma. Journal of Hepatology. 77(2):383-396. doi: 10.1016/j.jhep.2022.02.018. Elsevier. HKU Authors: Husain Abdullah, Elley YT Chiu, Karen MF Sze, YM Tsui, Eliana M S Suarez, X Zhang, LK Chan, Eva Lee, Joyce MF Lee, Clive YS Chung, TT Cheung, Carmen CL Wong, Daniel WH Ho, Irene OL Ng.
    • Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with confirmed SARS-CoV-2 infection during the omicron wave in Hong Kong: an observational study. Lancet. 400(10359):1213-1222, October 08, 2022. Total Page: P1171-1280. doi: 10.1016/S0140-6736(22)01586-0. Publisher: Elsevier Ltd. HKU Authors: Kristy TK Lau, Ivan CH Au, Eric HY Lau, Benjamin J Cowling, Gabriel M Leung, Carlos KH Wong.
    • Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses. Journal of Hepatology. 78(2):376-389. doi: 10.1016/j.jhep.2022.10.037. Elsevier. HKU Authors: PY Wong, Helen DG Xue, WH Yuen, Misty S Zhang, Y Zhang, YK Chan, David KC Chiu, CC Goh, Henry YH Lau, CT Law, PW Tse, Derek Lee, WS Cheu, Rex KH Au-Yeung, Jack CM Wong, Carmen CL Wong.
    • Carditis after COVID-19 Vaccination with a Messenger RNA Vaccine and an Inactivated Virus Vaccine. Annals of Internal Medicine. 175(3). doi: 10.7326/M21-3700. Name of publisher: American College of Physicians. PMID: 35073155. HKU Authors: K Peng, XN Tong, Celine SL Chui, Carlos KH Wong, X Li, P Ip, EYF Wan, Esther WY Chan, Ian CK Wong, Francisco TT Lai.
    • Global, regional, and national trends in opioid analgesic consumption from 2015 to 2019: a longitudinal study. Lancet Public Health. 2022, 7(4):335-346. doi: 10.1016/S2468-2667(22)00013-5. Published by Elsevier Ltd. Total no. of pages: e390. HKU Authors: Kenneth KC Man, TT Ma, Adrienne YL Chan, Esther WY Chan, Ian CK Wong, Celine SL Chui.
    • Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models. Gut. volume no: 72, issue no:2, page no: 242-255, doi: 10.1136/gutjnl-2022-327121. HKU Authors: SP Lee, SW Yun, Annie SY Chan, Dessy Chan, T Yin, April S Chan, HS Hui, Priscilla SW Cheng, CS Or, WY Tsui, Stephanie KY Ma, Simon YK Law, ST Yuen, SY Leung, Helen HN Yan.
    • Transmission of SARS-CoV-2 delta variant (AY.127) from pet hamsters to humans, leading to onward human-to-human transmission: a case study. Lancet. 399(10329):1070-1078. doi: 10.1016/S0140-6736(22)00326-9. HKU Authors: HL Yen, HG Gu, Lydia DJ Chang, Pavithra Krishnan, YM Ng, YZ Liu, Mani MY Hui, SY Ho, SF Sia, W Su, KT Choy, SY Cheuk, PN Lau, WY Tang, CT Koo, Louise Yung, MS Cheng, Malik Peiris, Gabriel M Leung, Leo LM Poon.
    • Modeling comparative cost-effectiveness of SARS-CoV-2 vaccinedose fractionation in India. Nature Medicine. 2022, Volume 28, P934-938, May 2022. doi: 10.1038/s41591-022-01736-z. HKU Authors: ZW Du, WW Lim, Eric HY Lau, P Wu, Benjamin J Cowling.
    • SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo. Nature. 2022 Mar. 603(7902):715-720. doi: 10.1038/s41586-022-04479-6. HKU Authors: KC Ng, KL Lai, K Tong, HG Gu, HH Ching, MC Cheung, John CW Ho, Kenrie PY Hui, Malik Peiris, John M Nicholls, Leo LM Poon, Michael CW Chan.
    • Physical activity and exercise for cancer-related cognitive impairment among individuals affected by childhood cancer: a systematic review and meta-analysis. Lancet Child & Adolescent Health. 7(1):47-58, 2023. doi: 10.1016/S2352-4642(22)00286-3. Name of publisher: Elsevier. HKU Authors: Joshua D K Bernal, Francesco Recchia, Daniel YT Fong, Danny J Yu, Parco MF Siu.
    • FGF21-Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity. Circulation. 2022;146(20):1537-1557. doi:10.1161/CIRCULATIONAHA.122.059631. HKU Authors: LL Geng, L Ying, LL Shu, RY Yang, Y Liu, Y Wang, X Jiang, Q Wang, QZ Lian, Connie WH Woo, Y Wang, ZY Xia, BY Liao, XQ Yan, LG Jin, AM Xu.
    • "Isoformic PD-1-mediated immunosuppression underlies resistance to PD-1 blockade in hepatocellular carcinoma patients. Gut. Published Online First: 30 November 2022. doi: 10.1136/gutjnl-2022-327133 HKU Authors: KY Kwan, L Li, ZW Tan, WY Chi, MS Chiu, YC Wong, M Yue, YQ Song, DY Zhou, YW Wang, XX Yang, JY Zhu, K Man, CM Lo, ZW Chen."
    • Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters. Science. 2022 Jul 22;377(6604):428-433. doi: 10.1126/science.abn8939. Publisher: American Association for the Advancement of Science (AAAS). HKU Authors: KM Tang, Anna JX Zhang, Vincent KM Poon, Chris CS Chan, Bobo WY Mok, ZZ Qin, YB Xie, Allen WH Chu, WM Chan, Jonathan D Ip, HR Sun, Kenn KH Chik, Chris CY Chan, JP Cai, CT Luo, L Lu, Cyril CY Yip, ZW Ye, CP Ong, Jessica OL Tsang, Terrence TT Yuen, SF Yuan, RH Liang, H Chu, DY Jin, Kelvin KW To, HL Chen, KY Yuen, Jasper FW Chan.
  • 2022
    • Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study.  The Lancet Infectious Diseases. 2022 Jan 1; 22(1):64-72. HKU Authors: Esther WY Chan, Celine SL Chui, Benjamin J Cowling, L Gao, Ivan FN Hung, Francisco TT Lai, Ivan CH Lam, KK Lau, X Li, Eric YF Wan, Ian CK Wong, Vincent KC Yan, Q Yu.
    • Brief advice, nicotine replacement therapy, sampling, and active referral for expectant fathers who smoke cigarettes. JAMA Internal Medicine. 2021 Aug 1;181(8):1081-1089. HKU Authors: CJ Hsieh, TH LAM, TT Luk, Kelvin MP Wang, YS Wu.
    • Circulating thrombospondin-2 as a novel fibrosis biomarker of non-alcoholic fatty liver disease in type 2 diabetes. Diabetes Care. 2021 Sep; 44(9):2089-2097. HKU Authors: Chole YY Cheung, WS Chow, Carol HY Fong, Karn SL Lam, Paul CH Lee, David TW Lui, Walter WK Seto, Helen Y Wan, YC Woo, A Xu, MF Yuen.
    • Effects of adjusting public health, travel, and social measures during the roll-out of COVID-19 vaccination: a modelling study. The Lancet Public Health. 2021;6(9):e674-e682. HKU Authors: Kathy SM Leung, Joseph TK Wu.
    • Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults: A Three-Group Randomized Controlled Trial. Annals of Internal Medicine. 2021;174(8):1050-1057. HKU Authors: Edwin C Chin, Parco MF Siu, Daniel Y Tak, Angus PH Yu, Doris SF Yu.
    • Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumor-propagating cells and their dynamic cellular transition during liver cancer progression. Gut. 2022 Aug;71(8):1656-1668. HKU Authors: CH Chan, Noelia Che, Joshua WK Ho, Jane HC Loong, Stephanie KY Ma, Elly SW Ngan, Kelvin Tan, M Tong, HJ Yu, Ken H Yu, Z Zhang, L Zhou
    • Multimodal investigation of rat hepatitis E virus antigenicity: Implications for infection, diagnostics, and vaccine efficacy. Journal of Hepatology. 2021 Jun;74(6):1315-1324. HKU Authors: JP Cai, Jasper FW Chan, WM Chan, H Chen, Nicholas FS Chew, J Situ, S Sridhar, L Wen, KY Yuen, S Wu, Anna JX Zhang.
    • Patient pIgR-enriched extracellular vesicles drive cancer stemness, tumorigenesis and metastasis in hepatocellular carcinoma. Journal of Hepatology. 2022 Apr;76(4): 883-895. HKU Authors: Janice YT Chan, HL Fung, Zoe Leung, Stephanie KY Ma, LY Mak, X Mao, Irene OL Ng, TH Ng, CF Sin, Alexander HN Tang, SK Tey, Danny KH Wong, Samuel WK Wong, Judy WP Yam, Cherlie LS Yeung, MF Yuen.
    • Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Cell Host Microbe. 2021 Apr;29(4):551-563. HKU Authors: J Cao, Chris CS Chan, Chris CY Chan, Jasper FW Chan, Z Chen, Kenn KH Chik, KY Kwan, C Li, S Li, L Liu, Vincent KM Poon, Kelvin KW To, H Xu, S Yuan, KY Yuen, Anna J Zhang, B Zhou, J Zhou, R Zhou.
    • Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial. Nature Medicine. 2021;27(10):1725-1734. HKU Authors: MF Yuen.
    • Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 Apr;184(8):2212–2228. HKU Authors: JP Cai, Jasper FW Chan, KH Chan, TK Chan, SY Fung, C Huang, J Jia, DY Jin, KL Siu, Jade LL Teng, Kelvin KW To, ML Yeung, KY Yuen, SY Yung, H Zhao, R Zhou.
    • Statin associated with lower cancer risk and related mortality in patients with heart failure. European Heart Journal. 2021 Aug;42(32)3049-3059. HKU Authors: KS Cheung, HL Li, X Li, QW Ren, HF Tse, PF Wong, MZ Wu, KH Yiu, SY Yu.
    • Two-dose COVID-19 vaccination and possible arthritis flare among patients with rheumatoid arthritis in Hong Kong. Annals of the Rheumatic Diseases. 2022 Apr;81(4):564-568. HKU Authors: Esther WY Chan, Celine SL Chui, P Kuan, Francisco TT Lai, CS Lau, Shirley X Li, X Tong, Eric YF Wan, Carlos KH Wong, Ian CK Wong, Winnie WY Yeung, Samson HH Yum.
    • Understanding longevity in Hong Kong: a comparative study with long-living, high-income countries. Lancet Public Health. 2021Dec;6(12):e919–e931. HKU Authors: Mathew SC Chow, Francis P Flores, SY Ho, TH Lam, Michael Y Ni, C Mary Schooling, J Shi, X Yao.
  • 2021
  • RSK2-inactivating mutations potentiate MAPK signaling and support cholesterol metabolism in hepatocellular carcinoma. Journal of Hepatology, 2021-02, Vol.74 (2), p.360-371.  HKU Authors: LK Chan, Daniel WH Ho, Charles Shing Kam, Elley YT Chiu, Carmen CL Wong, Kenneth SH Chok, Albert CY Chan, TT Cheung, CM Wong, Irene OL Ng.
  • Beta-amyloid deposition around hepatic bile ducts is a novel pathobiological and diagnostic feature of biliary atresia. Journal of Hepatology, 2020-12, Vol.73 (6), p.1391-1403. HKU Authors: Rosana Ottakandathil Babu, Vincent CH Lui, Rachel SW Yiu, Zhongluan Wu, Michelle ON Yu, Patrick HY Chung, Kenneth KY Wong, Urban Lendahl, Paul KH Tam.
  • Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles. Gut, 2020-12, Vol.69 (12), p.2165-2179. HKU Authors: Helen HN Yan, Hoi Cheong Siu, Siu Lun Ho, Sarah SK Yue, Yang Gao, Wai Yin Tsui, Dessy Chan, April S Chan, Jason WH Wong, Alice HY Man, Bernard CH Lee, Annie SY Chan, Anthony KW Chan, Ho Sang Hui, Arthur KL Cheung, Wai Lun Law, Oswens SH Lo, Siu Tsan Yuen, Suet Yi Leung.
  • Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong. Nature Medicine, 2020-11, Vol.26, p.1714-1719. HKU Authors: Dillon C Adam, Peng Wu, Jessica Y Wong, Eric HY Lau, Tim K Tsang, Gabriel M Leung, Benjamin J Cowling.
  • Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib - The CheckMate 040 Randomized Clinical Trial. JAMA Oncology, 2020-11-01, Vol.6 (11), p.e204564-e204564. HKU Authors: Thomas Yau.
  • Diverse effects of hepatic steatosis on fibrosis progression and functional cure in virologically quiescent chronic hepatitis B. Journal of Hepatology, 2020-10, Vol.73 (4), p.800-806. HKU Authors: LY Mak, Rex WH Hui, James Fung, Danny KH Wong, KS Cheung, MF Yuen, WK Seto.
  • Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood–brain barrier. European Heart Journal, 2020-09-01, Vol.41 (33), p.3169-3180. HKU Authors: Boya Liao, Leiluo Geng, Lingling Shu, Patrick KK Yeung, Karen SL Lam, Sookja K Chung, Paul M Vanhoutte, Aimin Xu, Ruby LC Hoo.
  • Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions. Science, 2020-08-28, Vol.369 (6507), p.1106-1109. HKU Authors: Sheikh Taslim Ali, Eric HY Lau, Gabriel M Leung, Benjamin J Cowling.
  • Association Between Treatment With Apixaban, Dabigatran, Rivaroxaban, or Warfarin and Risk for Osteoporotic Fractures Among Patients With Atrial Fibrillation: A Population-Based Cohort Study. Annals of Internal Medicine, 2020-07-07, Vol.173 (1), p.1-9. HKU Authors: Wallis CY Lau, CL Cheung, Kenneth KC Man, Esther W Chan, Chor Wing Sing, CW Siu, Joanne KY Lam, Alan CH Lee, Ian CK Wong.
  • Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. The Lancet, 2020-05-30, Vol.395 (10238), p.1695-1704. HKU Authors: Ivan FN Hung, Simon Sin, Pauline Yeung, Ricky Ruiqi Zhang, Agnes YF Fung, Erica YW Yan, KH Leung, Jonathan Daniel Ip, Allen WH Chu, WM Chan, Anthony CK Ng, Jasper FW Chan, CS Lau, KH Chan, Kelvin KW To, KY Yuen.
  • Respiratory virus shedding in exhaled breath and efficacy of face masks. Nature Medicine, 2020-05, Vol.26, p.676-680. HKU Authors: Nancy HL Leung , Daniel KW Chu, Eunice YC Shiu, KH Chan,  Benien JP Hau, HL Yen, Yuguo Li, Dennis KM Ip, JS Malik Peiris, WH Seto, Gabriel M Leung, Benjamin J Cowling.
  • Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. The Lancet Infectious Diseases, 2020-05, Vol.20 (5), p.565-574. HKU Authors: Kelvin KW To, Cyril CY Yip, JP Cai, LL Chen, WM Chan, KH Chan, Jonathan Daniel Ip, Anthony CK Ng, Rosana WS Poon, CT Luo, Vincent CC Cheng, Jasper FW Chan, Ivan FN Hung, Zhiwei Chen, Honglin Chen, KY Yuen.
  • First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment. The Lancet, 2020-04-25, Vol.395 (10233), p.1382-1393. HKU Authors: Kathy Leung, Joseph T Wu, Di Liu, Gabriel M Leung.
  • Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia. The New England Journal of Medicine, 2020-03-26, Vol.382 (13), p.1199-1207. HKU Authors: Peng Wu, Kathy SM Leung, Eric HY Lau, Jessica Y Wong, Tommy TY Lam, Joseph T Wu, Benjamin J Cowling, Gabriel M Leung.
  • Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study. The Lancet, 2020-02-29, Vol.395 (10225), p.689-697. HKU Authors: Joseph T Wu, Kathy Leung, Gabriel M Leung.
  • Depression and post-traumatic stress during major social unrest in Hong Kong: a 10-year prospective cohort study. The Lancet, 2020-01-25, Vol.395 (10220), p.273-284. HKU Authors: Michael Y Ni, Xiaoxin I Yao, Kathy SM Leung, Cynthia Yau, Candi MC Leung, Phyllis Lun, Francis P Flores, Wing Chung Chang, Benjamin J Cowling, Gabriel M Leung.
  • 2020
  • Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer. Nature communications, February 12, 2019, Vol.10(1), p.716. HKU Authors: Xinran Li, Victor CY Mak, Yuan Zhou, Esther SY Wong, Rakesh Sharma, Annie NY Cheung, Lydia WT Cheung.
  • Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187 897 patients. Gut, 26 November 2019, Vol.68(11), p.1979. HKU Authors: Ka-Shing Cheung, Lijia Chen, Esther W Chan, Wai-Kay Seto, Ian C K Wong, Wai K Leung*.
  • Indirect protection from vaccinating children against influenza in households. Nature communications, January 10, 2019, Vol.10(1), p.106. HKU Authors: Tim K Tsang, Vicky J Fang, Dennis KM Ip, Ranawaka APM Perera, Hau Chi So, Gabriel M Leung, JS Malik Peiris, Benjamin J Cowling.
  • Incidences, temporal trends and risks of hospitalisation for gastrointestinal bleeding in new or chronic low-dose aspirin users after treatment for Helicobacter pylori: a territory-wide cohort study. Gut, 17 March 2020, Vol.69(3), p.445. HKU Authors: Chuan-Guo Guo, Ka Shing Cheung, Feifei Zhang, Esther W Chan, Lijia Chen, Ian CK Wong, Wai K Leung.
  • Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses. Gastroenterology, December 2019, Vol.157(6), pp.1556-1571.e5. HKU Authors: Sin-Ting Lau, Zhixin Li, Frank PL Lai, Kathy Nga-Chu Lui, Peng Li, Elly Sau-Wai Ngan.
  • Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader. Nature communications, February 20, 2019, Vol.10(1), p.852. HKU Authors: Shaolin Liang, Andrew B Kinghorn, Raymond HW Li, Julian A Tanner.
  • Upconversion-like Photolysis of BODIPY-Based Prodrugs via a One-Photon Process. Journal of the American Chemical Society, November 6, 2019, Vol.141(44), pp.17482-17486. HKU Authors: Wen Lv, Yafei Li, Yaming Zhang, Weiping Wang.
  • Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9. Nature methods, August 2019, Vol.16(8), pp.722-730. HKU Authors: Gigi CG Choi, Peng Zhou, Chaya TL Yuen, Becky KC Chan, Feng Xu, Dawn Thean, Alan SL Wong.
  • Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression. Gut, 22 February 2020 (Published Online First 22 August 2019), Vol.69(2), p.329. HKU Authors: Jialing Shen, Mengnuo Chen, Derek Lee, Cheuk-Ting Law, Lai Wei, Felice HC Tsang, Don WC Chin, Carol LH Cheng, Joyce MF Lee, Irene OL Ng, Carmen CL Wong, Chun-Ming Wong.
  • Aberrant Super-Enhancer Landscape in Human Hepatocellular Carcinoma. Hepatology, June 2019, Vol.69(6), pp.2502-2517. HKU Authors: Felice HC Tsang, CT Law, Tsz-Ching Chloe Tang, Carol LH Cheng, Don WC Chin, Wing-Sum Vincy Tam, Lai Wei, Carmen CL Wong, Irene OL Ng, Chun-Ming Wong.
  • Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC. Nature communications, 15 October 2019, Vol.10(1), pp.4681. HKU Authors: Lai Wei, Derek Lee, Cheuk-Ting Law, Misty S Zhang, Jialing Shen, Don WC Chin, Allen Zhang, Felice HC Tsang, Ceci LS Wong, Irene OL Ng, Carmen CL Wong*, Chun-Ming Wong. 
  • Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation. The Journal of clinical investigation, February 1, 2019, Vol.129(2), pp.834-849. HKU Authors: Yong Pan, Xiaoyan Hui, Ruby LC Hoo, Cyrus YC Chan, Tianshi Feng, Yu Wang, Karen SL Lam, Aimin Xu.
  • Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection. Gastroenterology, April 2019, Vol.156(5), pp.1392-1403.e7. HKU Author: MF Yuen.
  • 2019
  • Temperature-responsive tungsten doped vanadium dioxide thin film starves bacteria to death. Materials Today. January-February 2019, Vol.22, pp.35-49. HKU Authors: Kenneth MC Cheung and Kelvin WK Yeung.
  • Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures. Lancet Respiratory Medicine. November 2018, Vol.6(11), pp.846-854. HKU Authors: Kenrie PY Hui, Rachel HH Ching, Stan KH Chan, John M Nicholls, JS Malik Peiris, Michael CW Chan.
  • Effects of Helicobacter pylori treatment on incidence of gastric cancer in older individuals. Gastroenterology. July 2018, Vol.155(1), pp.67-75. HKU Authors: Leung WK, Wong IOL, Cheung KS, Yeung KF, Chan EW, Wong AYS, Chen L, Wong ICK.
  • Long-term effects of discontinuation from antipsychotic maintenance following first episode schizophrenia and related disorders: a 10 year follow-up of a randomised, double-blind trial. Lancet Psychiatry (Article) 2018; Volume 5, Issue(5):432-442. HKU Authors: Christy LM Hui, Edwin HM Lee, Wing Chung Chang, Sherry KW Chan, Emily SM Chen, Pak Sham, Eric YH Chen.
  • Effectiveness of influenza vaccination on influenza-associated hospitalisations over time among children in Hong Kong: a test-negative case-control study. Lancet Respiratory Medicine. December 2018, Vol.6(12), pp.925-934. HKU Authors: Shuo Feng, Susan S Chiu, Eunice LY Chan, Yiu Chung Lau, Prof JS Malik Peiris, Prof Benjamin J Cowling.
  • Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases. The Lancet Psychiatry. October 2018, Vol.5(10), pp.824-835. HKU Authors: Man KKC, Ip P, Wong ICK.
  • Association of an Early Intervention Service for Psychosis With Suicide Rate Among Patients With First-Episode Schizophrenia-Spectrum Disorders. JAMA Psychiatry. 01 May 2018, Vol.75(5), pp.458-464. HKU Authors: Sherry KW Chan, Stephanie Wing Yan Chan, Herbert H. Pang, Kang K. Yan, Christy LM Hui, WC Chang, Edwin HM Lee, EYH Chen.
  • Characterizing the dynamics underlying global spread of epidemics. Nature Communications. 2018, Vol.9(1), pp.218-218. HKU Authors: Joseph T.Wu, Lin Wang.
  • Five-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM) on Diabetes-Related Complications and Health Service Uses—A Population-Based and Propensity-Matched Cohort Study. Diabetes Care. January 2018, Vol.41(1), pp.49-59. HKU Authors: Eric Yuk Fai Wan, Colman Siu Cheung Fung, Fang Fang Jiao, Esther Yee Tak Yu, Weng Yee Chin, Daniel Yee Tak Fong, Carlos King Ho Wong, Anca Ka Chun Chan, Karina Hiu Yen Chan, Cindy Lo Kuen Lam.
  • 2018
  • Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nature Communications (October 2017), Volume 8, Article number: 1185. HKU Authors: Jessica Aijia Liu*, Yanxia Rao, May Pui Lai Cheung, Man-Ning Hui, Ming-Hoi Wu, Lo-Kong Chan, Irene Oi-Lin Ng, Ben Niu, Kathryn S. E. Cheah, Rakesh Sharma & Martin Cheung.
  • Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial. European Heart Journal (March 2018) (online publish-ahead-of-print 18 February 2017), 39(12):1028-1037. HKU Authors: Haobo Li, Zhengyuan Xia.
  • Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. Nature Genetics (December 2017), 49(12):1722-1730. HKU authors: Tang CS, Cheung CYY, Cherny SS, Lam KSL, Tse HF, Sham PC.
  • Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study. Free Gut (January 2018) (Epub October 2017), 67(1):28-35. HKU authors: Ka Shing Cheung, Esther W Chan, Angel Y S Wong, Lijia Chen, Ian C K Wong, Wai Keung Leung†.
  • Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study. The Lancet Infectious Diseases (March 2017), Volume 17, No. 3, p339–347. HKU authors: Kathy Leung, Kwok Yung Yuen, Joseph T Wu.
  • SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop. Gut (December 2017), 66(12):2149-2159. HKU authors: Cui CP, Wong CC, Kai AK, Ho DW, Lau EY, Tsui YM, Chan LK, Cheung TT, Chok KS, Chan ACY, Lo RC, Lee JM, Lee TK, Ng IOL.
  • 2017
  • Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe-/- Mice. Circulation (June 2016), Volume 133, Issue 24, Pages 2434-2446. HKU authors: Jin Li, Paul M. Vanhoutte, Connie W. Woo, Aimin Xu.
  • Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin. JAMA Intern Med (June 2016), Volume 176, Issue 6, Pages 828-834. HKU authors: Angel Y. S. Wong; Ian C. K. Wong; Celine S. L. Chui; Edwin H. M. Lee; W. C. Chang; Eric Y. H. Chen; Wai K. Leung; Esther W. Chan.
  • Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia. Science (Jan 2016), Volume. 351, Issue 6268, Pages 81-84. HKU authors: Tommy T.-Y. Lam*, Lifeng Li*, Yongyi Shen, Yu Zhang, David K. Smith, Huachen Zhu†, Yi Guan.
  • Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. Nature Genetics (August 2016), Volume 48, No 8, Pages 940–946. HKU Authors: Yan Zhang*, Yong-Fei Wang, Ruoyan Chen, Tingyou Wang, Yu Lung Lau, Wanling Yang†.
  • Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia. Science Translational Medicine (Oct 2016), Volume 8, Issue 359, Pages 359ra129. HKU authors: Stephen S. Y. Lam*, Eric S. K. Ho*, Bai-Liang He, Wui-Wing Wong, Chae-Yin Cher, Nelson K. L. Ng, Cheuk-Him Man, Harinder Gill, Alice M. S. Cheung, Ho-Wan Ip, Chi-Chiu So, Yok-Lam Kwong and Anskar Y. H. Leung†.
  • Quantifying influenza virus diversity and transmission in humans. Nature Genetics (February 2016), Volume 48, No 2, Pages 195-200. HKU authors: Leo L M Poon*, Yi Guan, Joseph S M Peiris, Benjamin J Cowling†#.
  • RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation. Gut. 2017 Sep;66(9):1645-1656. doi: 10.1136/gutjnl-2016-311849. HKU authors: Helen H N Yan*, Jeffrey C W Lai*, Siu Lun Ho, Wai Keung Leung, Wai Lun Law, Anthony K W Chan, Wai Yin Tsui, Annie S Y Chan, Bernard C H Lee, Sarah S K Yue, Alice H Y Man, Siu Tsan Yuen†, Suet Yi Leung†.
  • Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis. PLOS Medicine (March 2016), Volume 13, No 3. HKU authors: Joseph T. Wu*†, Kathy Leung, Benjamin J. Cowling, Bingyi Yang, Eric H. Y. Lau & Gabriel M. Leung^.
  • 2016
  • Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation. Cell Metabolism (August 2015), Volume 22, Issue 2, p279–290. HKU authors: Xiaoyan Hui*, Ping Gu*, Jialiang Zhang, Yong Pan, Tianshi Feng, Cheng Zhong, Yu Wang, Karen S.L. Lam, Aimin Xu†.
  • Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair. Molecular Cell (October 2015), Volume 60, Issue 1, p163–176. HKU authors: Si Xie, Chengmin Qian†.
  • Dissemination, divergence and establishment of H7N9 influenza viruses in China. Nature (Letter) (June 2015), Volume 522, Issue 7554, pp. 102–105. HKU authors: Tommy Tsan-Yuk Lam*, Jia Wang*, Yujuan Chai*, Yongyi Shen*, Chi Ma, Lian Duan, Junfei Jiang, Yu Zhang, Lifeng Li, Leo Lit Man Poon, David K. Smith, Gabriel M. Leung, Joseph S. M. Peiris, Yi Guan† & Huachen Zhu†.
  • Prevention of Dabigatran-Related Gastrointestinal Bleeding With Gastroprotective Agents: A Population-Based Study. Gastroenterology (September 2015), Volume 149, Issue 3, Pages 586–595. HKU authors:Esther W. Chan*, Wallis C. Y. Lau*, Wai K. Leung, Ying He, Teresa S. M. Tong, and Ian C. K. Wong†.
  • 2015
  • Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. The Lancet (July 2013), Volume 382, Issue 9887, pp. 129 – 137. HKU authors: Benjamin J Cowling*, Eric HY Lau, Peng Wu, Tim K Tsang, Vicky J Fang, Michael Y Ni, Dennis KM Ip, Joseph T Wu, Gabriel M Leung†.
  • Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. The Lancet (July 2013), Volume 382, Issue 9887, pp. 138 – 145. HKU authors: Bnjamin J Cowling*, Eric HY Lau*, Tim K Tsang, Peng Wu, Vicky J Fang, Joseph T Wu† and Gabriel M Leung.

HKU’s Honorary University Fellowship

• Professor SP Chow, Department of Orhopaedics and Traumatology

Outstanding Researcher Award (ORA)

• Professor Z Chen, Department of Microbiology (2020-21)
• Professor IFN Hung, Department of Medicine (2018-19)
• Professor BJ Cowling, School of Public Health (2016-17)
• Professor LLM Poon, School of Public Health (2016-17)
• Professor SCW Tang, Department of Medicine (2015-16)
• Professor J Huang, School of Biomedical Sciences (2014-15)
• Professor Y Guan, School of Public Health (2013-14)
• Professor Z Zhou, School of Biomedical Sciences (2013-14)
• Professor L Lu, Department of Pathology (2012-13)
• Professor X Guan, Department of Clinical Oncology (2011-12)
• Professor RMF Yuen, Department of Medicine (2009-10)

Outstanding Young Researcher Award (OYRA)

• Dr LWT Cheung, School of Biomedical Sciences (2021-22)
• Dr JFW Chan, Department of Microbiology (2020-21)
• Dr MYX Ni, School of Public Health (2020-21)
• Dr EWY Chan, Department of Pharmacology and Pharmacy (2017-18)
• Dr VHF Lee, Department of Clinical Oncology (2017-18)
• Dr WKW Seto, Department of Medicine (2016-17)
• Dr CCL Wong, Department of Pathology (2016-17)
• Dr JA Tanner, School of Biomedical Sciences (2015-16)
• Dr H Zhu, School of Public Health (2015-16)
• Dr JTK Wu, School of Public Health (2013-14)
• Dr JJ Wang, School of Biomedical Sciences (2011-12)

Outstanding Research Student Supervisor Award (ORSSA)

• Dr CM Wong, Department of Pathology (2021-22)
• Professor Z Chen, Department of Microbiology (2020-21)
• Professor AYH Leung, Department of Medicine (2017-18)
• Dr JA Tanner, School of Biomedical Sciences (2016-17)
• Professor XY Guan, Department of Clinical Oncology (2015-16)
• Professor DY Jin, School of Biomedical Sciences (2013-14)
• Professor ANY Cheung, Department of Pathology (2011-12)
• Professor YS Chan, School of Biomedical Sciences (2009-10)

Faculty Knowledge Exchange Award

• Professor Z Chen, Department of Microbiology (2019)
• Professor MF Yuen, Department of Medicine (2018)
• Dr KS Cheung, Department of Medicine (2018)
• Dr WKW Seto, Department of Medicine (2018)
• Dr DK Wong, Department of Medicine (2018)
• Dr EHY Lau, School of Public Health (2018)
• Professor JTK Wu, School of Public Health (2018)
• Professor D Chan, School of Biomedical Sciences (2017)
• Dr BHY Chung, Department of Paediatrics and Adolescent Medicine (2017)
• Dr MKT To, Department of Orthopaedics and Traumatology (2017)
• Professor KMC Cheung, Department of Orthopaedics and Traumatology (2016)
• Professor KDK Luk, Department of Orthopaedics and Traumatology (2016)