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research scription

The major focus of his research is use novel drugs against HIV; Viral infection and protective immune response. Right now his research interest mainly focusses on what and how specific molecules are involved in DC-mediated T cell activation and immune tolerance during viral infection.

selected Publication

Zhou RH, Wang X, Liu H, Guo L, Su QJ, Wang H, Vasiliadis T, Persidsky Y, Ho WZ and Li JL. GalNAc-specific soybean lectin inhibits HIV infection of macrophages through indunction of antiviral factors. J Virol 2018; 92(6). Pii: e01720-17.

Zhou RH, Guo L, Liu JB, Liu H, Hou W, Ma TC, Wang X, Wu JG, Ye L, Ho WZ, Li JL. Epigallocatechin Gallate Inhibits Macaque SEVI-Mediated Enhancement of SIV or SHIV Infection. J Acquir Immune Defic Syndr 2017; 75:232-240.

Lin XD, Zhou RH, Fan FN, Ying XH, Sun XY, Wang W, Holmes EC, Zhang YZ. Biodiversity and evolution of Imjin virus and Thottapalayam virus in Crocidurinae shrews in Zhejiang Province, China. Virus Res 2014; 189:114-120. (co-first author)

Xu XQ, Guo L, Wang X, Liu Y, Liu H, Zhou RH, Gu J, Liu JB, Xu P, Zhou L, Ho WZ. Human Cervical Epithelial Cells Release Antiviral Factors and Inhibit HIV Replication in Macrophages. J Innate Immunol 2018; 20:1-12.

Liu JB, Li JL, Zhuang K, Liu H, Wang X, Xiao QH, Li XD, Zhou RH, L. Zhou L, Ma TC, Zhou W, Liu MQ and Ho WZ. Epigallocatechin-3-gallate local pre-exposure application prevents SHIV retal infection of macaques. Mucosal Immunol 2018

Guo LXu XQZhou LZhou RHWang XLi JLLiu JBLiu HZhang BHo WZ. Human intestinal epithelial cells release antiviral factors that inhibit HIV infection of macrophages. Front Immunol 2018; 19;9:247.

Ma TC, Guo L, Zhou RH, Wang X, Liu JB, Li JL, Zhou Y, Hou W, Ho WZ. Soybean-derived Bowman-Birk Inhibitor (BBI) blocks HIV entry into macrophages. Virology 2018; 513:91-97.

Wang X, Wang H, Liu MQ, Li JL, Zhou RH, Zhou Y, Wang YZ, Zhou W, Ho WZ. IFN-lambda Inhibits Drug-Resistant HIV Infection of Macrophages. Front Immunol 2017; 8:210.

Lin XD, Wang W, Hao ZY, Wang ZX, Guo WP, Guan XQ, Wang MR, Wang HW, Zhou RH, Li MH, Tang GP, Wu J, Holmes EC, Zhang YZ. Extensive diversity of coronaviruses in bats from China. Virology 2017; 507:1-10.

Sun L, Wang X, Zhou Y, Zhou RH, Ho WZ, Li JL. Exosomes contribute to the transmission of anti-HIV activity from TLR3-activated brain microvascular endothelial cells to macrophages. Antiviral Res 2016; 134:167-171.

Ma TC, Zhou RH, Wang X, Li JL, Sang M, Zhou L, Zhuang K, Hou W, Guo DY, Ho WZ. Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages. Sci Rep 2016; 6:34752.

Wang W, Lin XD, Guo WP, Zhou RH, Wang MR, Wang CQ, Ge S, Mei SH, Li MH, Shi M, Holmes EC, Zhang YZ. Discovery, diversity and evolution of novel coronaviruses sampled from rodents in China. Virology 2015; 474:19-27.

Wang W, Wang MR, Lin XD, Guo WP, Li MH, Mei SH, Li ZM, Cong ML, Jiang RL, Zhou RH, Holmes EC, Plyusnin A, Zhang YZ. Ongoing spillover of Hantaan and Gou hantaviruses from rodents is associated with hemorrhagic fever with renal syndrome (HFRS) in China. PLoS Negl Trop Dis 2013; 7:e2484.

Guo WP, Lin XD, Wang W, Tian JH, Cong ML, Zhang HL, Wang MR, Zhou RH, Wang JB, Li MH, Xu J, Holmes EC, Zhang YZ. 2013. Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents. PLoS Pathog 2013; 9:e1003159.

周润宏, 霍文哲. 精液源性多肽促HIV感染及相关拮抗物的研究进展. 中国艾滋病性病2016 (22), 7: 582-586.