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research description

My research interest is antibody engineering with broadly neutralizing antibodies (bnAbs) against influenza virus infections. The main focuses of my study are engineering bi-bnAbs and developing novel antibodies to improve the potency and breadth of current strategies against multiple influenza strains.

selected Publication

Wang Y, Jin R, Shen B, Li N, Zhou H, Wang W, Zhao Y, Huang M, Fang P, Wang S, Mary P, Wang R, Ma P, Li R, Tian Y, Cao Y, Li F, Schweizer L, Zhang H. High-throughput functional screening for next-generation cancer immunotherapy using droplet-based microfluidics. Science Advances. 2021 Jun 11;7(24) :eabe3839. doi: 10.1126/sciadv.abe3839.

Chen D, Zhao Y, Li M, Shang H, Li N, Li F, Wang W, Wang Y, Jin R, Liu S, Li X, Gao S, Tian Y, Li R, Li H, Zhang Y, Du M, Cao Y, Zhang Y, Li X, Huang Y, Hu LA, Li F, Zhang H. A general Fc engineering platform for the next generation of antibody therapeutics.Theranostics. 2021 Jan 1;11(4):1901-1917. doi: 10.7150/thno.51299.