Department of Ophthalmology

Research Questions

  • How do we prevent blindness?
Research student in a lab
Research Areas

1. Diabetic Retinopathy Screening 


2. Improving Outcome of Glaucoma Interventions

  • Augmentation and modification of trabeculectomy
  • Minimally invasive glaucoma surgeries
  • Effect of long-term glaucoma medications on subsequent glaucoma surgery


3. Cataract Surgery

  • Patient experience
  • Output measurements and improvements

Dr JCH Chan


4. Biomedical Engineering

  • Tissue engineering: All-aqueous immiscible liquid-liquid system as platforms to form cellular structures for potential transplantation purposes in the eye
  • Building in vitro physiologically representative models: Eye-on-a-chip microfluidic platforms
  • Surgical research on vitreoretinal surgery: Procedures modification, Intraoperative tools, endotamponades and micro-surgical devices

Dr JYK Chan


5. Neuroprotection and Regeneration in Models of Retinal Neurodegeneration

  • Trans-scleral electrical stimulation in traumatic optic neuropathy, retinal ischaemia reperfusion injury, and chronic glaucoma models in rats/rabbits
  • Immune modulatory effects of the traditional Chinese medicine Lycium barbarum in Alzheimer's disease-related vision loss
  • Mesenchymal stem cell-mediated rescue in mitochondrial dysfunction-related retinal ganglion cell degeneration in glaucoma models in rats/rabbits
  • Photobiomodulation of retinal ganglion cell survival in rabbit retinal ischaemia reperfusion injury.
  • Continuous monitoring of electroretinogram using a wireless apparatus

Dr CK Chiu


6. Glaucoma

  • Prevention of glaucoma progression with new treatment modalities and lifestyle modification.
  • Collagen crosslinking − its clinical application in glaucoma-related diseases and others
  • Enhancement of disease detection and monitoring
  • Myopia control

Dr BNK Choy

  • Treatment of acute and chronic angle-closure glaucoma
  • Risk factors and neuroprotection in normal-tension glaucoma

Professor JSM Lai


7. Surgical and Medical Retina

  • Age-related macular degeneration, diabetic retinopathy, retinal vascular disease
  • Paediatric retinal diseases
  • Retinopathy of prematurity
  • Medical education

Professor WC Lam


8. Ocular Surface Oncology

  • Epidemiology of ocular surface tumours
  • Role of micro-organisms in pathogenesis of ocular surface tumours
  • Evidence based practice in management of ocular surface tumours


9. Ophthalmic Microbiology

  • Antimicrobial susceptibility of ophthalmic pathogens
  • Microbiology of the ocular surface
  • Antimicrobial stewardship in ophthalmology

Dr A Lee


10. Protecting the Eye and the Brain

  • Protecting the developing retina − ocular angiogenesis, retinopathy of prematurity, oxygen-induced retinopathy
  • Protecting the ageing retina − retinal ischaemia/reperfusion injury, diabetic retinopathy
  • Protecting the brain − cerebral ischaemia/reperfusion injury, stroke
  • Bioengineering − cell-based and optogenetics-controlled drug delivery
  • Development of novel molecular and cellular therapeutic approaches for ocular and cerebral diseases



11. Anterior Segment

  • Epidemiology and novel treatment methods in dry eye disease
  • In-vitro modelling of dry eye disease
  • Pathophysiology and treatment of corneal neuropathy
  • Treatment of sight-threatening ocular surface disease


12. Retinal Neuroprotection

  • Transcorneal electrical stimulation as a neuroprotective strategy in retinal disease
  • In-vitro modelling of the effect of retinal electrical stimulation

Dr KC Shih


13. Clinical Researches in Glaucoma

  • Glaucoma assessments and treatments
  • Minimally invasive glaucoma surgeries


14. Translational Ophthalmic Researches

  • Novel glaucoma treatment modalities
  • Intraocular drug delivery systems
  • Artificial intelligence on ophthalmic imaging
  • Ocular imaging technologies

Dr JKW Wong

Next Step?

For more information or to express interest to join the research areas, please email the supervisor or the specified contact point in the description. Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Research postgraduate studies enquiries specific to the department/school’s research should be directed to the Chairman of the Departmental Research Postgraduate Committee:


Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website.

General admission enquiries should be directed to

Our Students

A research student working in a laboratory.
Jane Smith (Example)

Country of origin: Name of country
Progress: PhD Year X
Supervisor: Dr AB Chan

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May 2021