Big Data and Precision Medicine

1. ATOH8 depletion can reprogram non-cancer stem cells into cancer stem cells in hepatocellular carcinoma
   Yangyang Song, Leilei Chen, Tim Hon Man Chan, Yan Li, Ming Liu and Xin-Yuan Guan*
   The University of Hong Kong
   
2. Panel testing for gene mutations in acute myeloid leukaemia by next-generation sequencing
   Chun Hang Au*, Wing Yi Wa*, Dona N Ho, Tsun Leung Chan, Edmond S K Ma#
   Hong Kong Sanatorium and Hospital
   *Equal contribution
   #Correspondence to Dr Edmond S K Ma
   
3. Evaluation of genetic modified Salmonella Typhimurium as a targeted therapy for neuroblastoma: Comparison of response of orthotopic mouse models with different immunological background
   ZL Guo, B Yu, JD Huang, GCF Chan
   The University of Hong Kong
   
4. GWASdb2.0: a database for human genetic variants identified by genome-wide association studies
   MulinJun Li^1†, Zipeng Liu^1†, PanwenWang¹, Maria P Wong¹, Meredith Yeager², Pak Chung Sham¹, Stephen J Chanock², Zhengyuan Xia¹, Junwen Wang¹*
   ¹ The University of Hong Kong
   ² NIH, Bethesda, MD, USA
   †Both authors contributed equally to this work
   
5. Surveillance along the pig value chain for the detection of swine influenza in Northern Vietnam
   Eugénie Baudon^1,2, Dao Duy Tung³, Leo L.M. Poon¹, Pham Thi Nga³, Benjamin J. Cowling¹, Marisa Peyre², Nguyen Viet Khong³, Malik Peiris^{1
   1} The University of Hong Kong
   ² French Agricultural Research Center for International Development (CIRAD), Montpellier, France
   ³ Institute of Veterinary Research, Hanoi, Vietnam
   
6. Association between antibody titers and protection against influenza virus infection within households
   Tim K. Tsang¹, Simon Cauchemez², R.A.P. Mahen Perera¹, Guy Freeman¹, Vicky J. Fang¹, Dennis K.M. Ip¹, Gabriel M. Leung¹, J.S. Malik Peiris¹, Benjamin J. Cowling^{1
   1}The University of Hong Kong
   ²Institut Pasteur, Paris
   
7. Whole transcriptome analysis reveals gene expression differences between sexes, possible sex specific regulation and contribution to differential disease prevalence between sexes
   Shen, J.J., Wang, T.Y., Yang, W.L.
   The University of Hong Kong
   
8. Genome-wide haplotype-based association study in Chinese Han population identified novel susceptibility locus for systemic lupus erythematosus
   Yongfei Wang, Yan Zhang, Jing Yang, Yulung Lau, Wanling Yang
   The University of Hong Kong
   
9. Diabetic retinopathy genetic variants identified in genome-wide association studies and the risk of microvascular complications in Chinese diabetic patients
   Chloe YY Cheung, Elaine YL Hui, Kelvin HM Kwok, Carol HY Fong, Rachel LC Wong, Chi Ho Lee, Michele Yuen, Yu Cho Woo, Chun Yip Yeung, Wing Sun Chow, Pak C Sham, and Karen SL Lam
   The University of Hong Kong
   
10. Perceived benefits and harms of alcohol drinking and their association with parental drinking and pro-drinking practices in Hong Kong adolescent
    Au WM, Ho SY, Wang MP, Huang R, Lam TH
    The University of Hong Kong
    
11. "Proteoglycan profile" and Level-Specific Biomarker of Lumbar Disc Displacement
    Henry Pang¹, Edward Hui¹, Cora Bow¹ Jason Cheung¹, Ari Borthakur², Jaro Karppinen³ Kenneth Cheung¹, Dino Samartzis^{1
    1} The University of Hong Kong
    ² University of Pennsylvania, Philadelphia, Pennsylvania, USA
    ³ University of Oulu and Oulu University Hospital, Oulu, Finland
    
12. Doctor-diagnosed Gastro-Oesophageal Reflux Disease in Hong Kong adolescents: prevalence and atypical symptoms
    Mok HY, Ho SY, Yung D, Lo WS, Lam TH
    The University of Hong Kong
    
13. Survey on cancers' researches related to Chinese herbal medicine and free radicals
    Lam WL, Lao LX, Yeung WF, Chen HY
    The University of Hong Kong
    
14. Night-eating in Hong Kong adolescents: prevalence and associations with dinner habits, bedtime and weight status
    Huang Y, Ho SY, Huang R, Lo WS, Lam TH
    The University of Hong Kong
    
15. Self-reported halitosis in Hong Kong adolescents: prevalence and association with socio-demographic characteristics and self-rated health
    Tamrakar M, Ho SY, Huang R, Lo WS, Lam TH
    The University of Hong Kong
    
16. Quitting smoking and mortality: risk of all-cause mortality decreased sharply in 5-9 years after quitting among Chinese
    ZM Mai, SY Ho, MP Wang, CMM Lo and TH Lam
    The University of Hong Kong
    
17. Doctor-diagnosed sleep apnoea in Hong Kong adolescents: prevalence and associations with night-eating and dinner time
    Dai SY, Ho SY, Mok HY, Yung D, Lo WS, Lam TH
    The University of Hong Kong
    
18. Perceived drinking prevalence in adolescents, parents, teachers and doctors, and its association with adolescent drinking and intention to drink
    Huang R, Ho SY, Wang MP, Lam TH
    The University of Hong Kong
    
19. The fraction of influenza virus infections that are asymptomatic: a systematic review and meta-analysis
    Nancy H. L. Leung*, Cuiling Xu, Dennis K. M. Ip, Benjamin J. Cowling
    The University of Hong Kong
    
20. Daily total fluid intake and changes in body mass index among Hong Kong primary school students
    RuanRL¹, Ho SY¹, Tin SPP¹, Chen JJ¹, Lee KY², Chung WH², Lam TH^{1
    1}The University of Hong Kong
    ²Department of Health, Government of HKSAR
    
21. Aided smoking cessation and its association with smoking urge in the morning and smoking intention in Hong Kong adolescent ex-smokers
    Leung LT, Ho SY, Wang MP, Lo WS, Lam TH
    The University of Hong Kong
    
22. Fidgeting in Hong Kong adolescents and its associations with physical activity and weight status
    Yung D, Ho SY, Lo WS, Lam TH
    The University of Hong Kong
    
23. Family smoking, home smoking ban and morning and heavier smoking in adolescent smokers
    Chen JJ, Ho SY, Wang MP, Leung LT, Lo WS, Lam TH
    The University of Hong Kong
    
24. Aptamer Library Resampling
    AB KINGHORN and JA Tanner
    The University of Hong Kong