Research Projects
Next Generation Sequencing of Epstein-Barr Virus Genomes in Cancer Tissues and Saliva


Programme(s) to which this project applies:
☒ MPhil/PhD ☑ MRes[Med] ☒ URIS

Objective and Significance:

Sequence analysis of EBV genomic variations/mutations in EBV infection subjects and EBV-positive malignancies. Development of novel assays in characterizing EBV strains to study distribution and inter-change of EBV strains among different body compartments and to discover pathogenic viral strains in malignancies.

Research Plan and Methodology:

The Chiang lab has established a novel protocol to enrich EBV DNA in clinical samples for subsequent downstream next generation sequencing and de novo assembly of whole EBV genomes. New variations and mutations of pathogenic significance will be actively analyzed. A cryobank of clinical tissues is established for such studies.

Dr AKS Chiang, Department of Paediatrics and Adolescent Medicine

Biography
chiangak@hku.hk

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to rpgmed@hku.hk.

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information. 

Research @ Department of Paediatrics and Adolescent Medicine