Research Projects
Trajectories and phase transition in the Clinical High Risk for Psychosis Population as compared with the Clinical High Risk for Mood Disorder Population: a neuroimaging, electrophysiological, neurocognitive, and experience sampling study

Programme(s) to which this project applies:

☑ MPhil/PhD ☑ MRes[Med] ☑ URIS

Objective and Significance:

- To examine a range of potential risk factors for young people at Ultra High Risk (UHR) for psychosis, with the aim of creating tools to better predict outcomes and develop the best possible treatment plans

Research Plan and Methodology:

Students will have opportunities to be involved in an international collborative study in which large number of youths with risk for psychosis will be recruited across Australia, Asia and Europe in two years. Participants will be followed monthly in the first year and biyearly in the second year. The study collect a broad range of information about their symptoms, family history and biology. Research components include clinical interviews, neurocognitive tasks, electrical brain activity recording (EEG), brain imaging scan (MRI), blood sample for biomarkers, saliva sample for stress hormone, speech sample, video sample and momentary mood and behaviour through a smartphone app.

Professor EYH Chen, Chair Professor, Department of Psychiatry

HKU Scholars Hub
Laboratory Homepage

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.