Research Projects
Cracking down bacterial infection though novel bio-nanoparticles

Programme(s) to which this project applies:

☑ MPhil/PhD ☒ MRes[Med] ☒ URIS

The infections induced by multidrug-resistant (MDR) Gram-positive or -negative bacteria are emerging and disseminating rapidly, undoubtedly posing an urgent threat to global public health. Here, we discover that antibiotic resistant mechanism becomes compromised when the infections are treated by our novel bio-nanoparticles driven by external photo (light), microwave or ultrasound sources.

Additionally, those bio-nanoparticles can easily embed into hydrogels or on implant surface that enable us addressing various kinds of wound or deep tissue infections.

Professor KWK Yeung, Department of Orthopaedics and Traumatology

Kelvin Yeung has been passionate about applied orthopaedic biomaterial research and translation for more than 20 years. His major research areas include orthopedic biomaterials, antibacterial coatings, 3D bio-printing and musculoskeletal tissue engineering.

He is currently a tenured full professor in the Department of Orthopaedics and Traumatology, The University of Hong Kong, Director of Research Laboratory of Orthopaedic Centre & Deputy Director of Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma, The University of Hong Kong Shenzhen Hospital. His h-index is 60 (Scopus) with 12,000> citations and 67 (Google Scholar) with 15,000> citations. He has been consecutively ranked as the World’s Top 1% of Scientists in the field of biomaterials by Clarivate Analytics’ Essential Science Indicators (ESI) from 2014 to 2021. In addition to publishing more than 270 peer-reviewed SCI journal papers and filing 41 full patents in various countries, he co-founded OrthoSmart Limited with two senior colleagues to adapt their research findings for clinical use. He was the interim CEO and now serves as one of the directors in this startup company. Furthermore, he has been invited to act as a consultant for several medical device and biomaterial corporations.

During these years, he participated in local and regional competitions and received a number of awards and scholarships, including the Young Scientist Award 2005 and the Young Engineer Award 2009 and Faculty Research Output Award 2019. For projects in which he has acted in the capacity of principal investigator or co-principal investigator, he has received over HK$83,000,000. Furthermore, he has received 20 prizes and awards from local and international competitions and conferences. He has been invited to deliver 80 plenary lectures, keynotes or invited talks at international and regional conferences. Professor Yeung is an active member of local and international academic bodies and has served in several executive positions. He is also the Associate Editor of Bioactive Materials Journal (Impact factor (2019): 14.593, Ranking: 1/40 in materials science (Biomaterials)).

HKU Scholars Hub

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.