HKUMed on COVID-19
COVID-19 Vaccines, a Prospective Follow-up Study | 2019冠狀病毒病疫苗,一項前瞻性跟進研究

COVID-19 vaccination will be able to reduce transmission and severity of COVID-19 infection.

In this prospective study, the HKU Department of Medicine plans to recruit adult subjects 18 years or above. Recruited subjects will receive the COVID-19 vaccine of their own choice. All recruited subjects will be follow-up and assessed for a total of 1 year for vaccine immunogenicity and safety. 



Content | 研究內容

The aim of this study is to investigate the immunogenicity profile of people getting vaccinated.

Volunteers will be required to:

  • Perform screening procedure by completing a simple health assessment 
  • Sign a consent and take blood and saliva tests for antibodies before proceeding to vaccination
  • Complete the vaccination diary after the first and second vaccination to monitor the adverse effects post-vaccination. We will follow-up on the adverse effects and immunogenicity of all vaccinees
  • Join a total of five blood and saliva tests:
  1. The day of 1st dose of vaccine
  2. The day of the 2nd dose of vaccine
  3. Four weeks after the 2nd dose of vaccine
  4. Half a year after the 1st dose of vaccine
  5. One year after the 1st dose of vaccine



  • 通過完成簡單的健康評估來執行篩查程序

  • 在進行疫苗接種前簽署同意書並進行血液和唾液檢測以檢測抗體

  • 在第一次注射疫苗及第二次注射疫苗後,填寫注射疫苗日記,以監察疫苗的副作用。我們會跟進及監察參與者對疫苗的反應及免疫力數據

  • 參加總共五次血液和唾液測試

  1. 注射第一劑疫苗當天
  2. 注射第二劑疫苗當天
  3. 注射第二劑疫苗之後的四個星期
  4. 注射第一劑疫苗的半年後
  5. 注射第一劑疫苗的一年後
Venue | 研究地點

The research will be carried out at:

  • Sinovac CoronaVac’: Sai Ying Pun Jockey Club General Out-patient Clinic
  • BioNTech ‘Comirnaty’: Community Vaccination Centre at Sun Yat Sen Memorial Park Sports Centre


  • 科興「克爾來福」疫苗:西營盤賽馬會普通科門診診所
  • BioNTech「復必泰」疫苗:中山紀念公園體育館社區疫苖接種中心
Eligibility | 參與資格

A sincere invitation to healthy volunteers to participate in this clinical study.

Participants must meet the following criteria:

  • No uncontrolled chronic illness
  • No known drug allergy history


  • 沒有不受控的長期病患
  • 沒有對任何疫苗或外來物質產生嚴重過敏反應
Enquiries | 聯絡研究團隊

If you have any further question about this study, please contact study nurse Miss Deborah Ho at HKU Department of Medicine:


+852 6067 1500
+852 6067 1500