Frontier in Biomedical Research 2004

THE UNIVERSITY OF HONG KONG
FACULTY OF MEDICINE

Frontiers in Biomedical Research, HKU 2004
Friday, December 3, 2004
Cheung Kung Hai Conference Centre, G/F
William MW Mong Block
Faculty of Medicine Building

Morning Session
9:00 – 9:15	Opening Ceremony - Officiating address by Professor Lap-Chee Tsui, Vice-Chancellor - Welcoming address by Professor SK Lam, Dean of the Faculty of Medicine - Group photo
9:15 – 9:55 9:55 – 10:35	Chairpersons: Professor TH Lam, Community Medicine Professor George SW Tsao, Anatomy Keynote Lecture I Intravital Imaging: An interdisciplinary approach towards following complex events within intact biological systems Professor Scott E Fraser California Institute of Technology, USA Keynote Lecture II Public health, genetics and health policy Dr Ron Zimmern Public Health Genetics Unit, University of Cambridge, UK
10:35 – 11:00	Tea Break
11:00 – 13:00	5 Parallel Sessions
13:00 – 14:00	Lunch
Afternoon Session
14:00 – 14:40 14:40 – 15:20	Chairpersons: Professor Ralf Altmeyer, HKU-Pasteur Research Centre Professor KF So, Anatomy Keynote Lecture X Interaction of Salmonella with its mammalian host cells Professor Jorge E Galan Yale University School of Medicine, USA Keynote Lecture XI Cell-based therapies of spinal cord injury Professor Wise Young Rutgers, the State University of New Jersey
15:20 – 15:45	Tea Break
15:45 – 16:25	Chairperson: Professor Paul KH Tam, Surgery Keynote Lecture XII Frontiers in biomedical research: a publisher's perspective Dr Beatrice Renault Nature Research Journals, USA
16:30 – 18:10	5 Parallel Sessions
18:10 – 18:50	Chairpersons: Dr Raymond TF Cheung, Medicine Professor Paul Vanhoutte, Biopharmaceutical Development Centre Keynote Lecture XVII Genome architecture, rearrangements, evolution, and genomic disorders Professor James R Lupski Baylor College of Medicine, USA
1. Cancer: Joint Scientific Meeting of the Cancer Research Centre, Centre of Alimentary Research & Education, Centre for Cellular Biology and Centre for the Study of Liver Disease
Morning Parallel Session
11:00 – 11:40 11:40 – 12:00 12:00 – 12:20 12:20 – 12:40 12:40 – 13:00	Chairpersons: Professor Raymond HS Liang, Medicine Dr Ronnie TP Poon, Surgery Keynote Lecture III New approaches to cancer immunotherapy Professor Xuetao Cao Tsinghua University, China Molecular and genetic alterations of hepatocellular carcinoma Professor Irene OL Ng, Pathology BS69 specifically scaffolds latent membrane protein 1 and TRAF6 to activate the JNK and NF-kB pathways Dr Zhenguo Wu Department of Biochemistry, Hong Kong University of Science and Technology Targeting Inhibitors of Apoptosis Proteins in Treatment of Cancer Dr Benjamin CY Wong, Medicine Therapeutic options of hepatocellular carcinoma Dr CL Liu, Surgery
Afternoon Parallel Session
16:30 – 16:50 16:50 – 17:10 17:10 – 17:30 17:30 – 17:50 17:50 – 18:10	Chairpersons: Professor George SW Tsao, Anatomy Professor PW Yuen, Surgery Plasma nucleic acids as a new class of tumour markers Professor Dennis YM Lo Department of Chemical Pathology, The Chinese University of Hong Kong The development of arsenic as an anti-cancer drug Professor YL Kwong, Medicine Genetic markers for gestational trophoblastic diseases Dr Annie NY Cheung, Pathology Delineation of prognostic markers in gastric cancer by expression profiling Dr SY Leung, Pathology Human telomerase reverse transcriptase and cancer Dr Marie CL Lin, Institute of Molecular Biology
2. Healthy Aging: Joint Scientific Meeting of the Centre of Endocrinology & Diabetes, Institute of Cardiovascular Science & Medicine and Neuroscience Research Centre
Morning Parallel Session
11:00 – 11:20 11:20 – 12:00 12:00 – 12:20 12:20 – 12:40 12:40 – 13:00	Chairpersons: Professor YS Chan, Physiology Professor Karen SL Lam, Medicine Functional MRI and acupuncture in recovery after stroke Dr Raymond TF Cheung, Medicine Keynote Lecture IV The basal ganglia in health and disease Professor J Paul Bolam University of Oxford, UK Failure of the Elderly Heart Professor CP Lau, Medicine Id-1 as a marker for advanced prostate cancer Professor YC Wong, Anatomy The effect of pregnancy on the body mass index in Southern Chinese women in the reproductive age Professor Terence TH Lao, Obstetrics & Gynaecology
Afternoon Parallel Session
16:30 – 17:10 17:10 – 17:30 17:30 – 17:50 17:50 – 18:10	Chairpersons: Dr Raymond TF Cheung, Medicine Professor Paul Vanhoutte, Biopharmaceutical Development Centre Keynote Lecture XIII Translational research in Switzerland: From human vascular cells to clinical trials Professor Thomas F Lüscher University of Zurich, Switzerland A local angiotensin – generating system in the carotid body for the adaptation to hypoxia Dr ML Fung, Physiology Glycation and oxidation in age-related diseases Dr Kathryn CB Tan, Medicine Neuroprotection in PD Dr SL Ho, Medicine
3. Infection and Immunology: Joint Scientific Meeting of the Centre of Infection and Immunology Group
Morning Parallel Session
11:00 – 11:20 11:20 – 11:40 11:40 – 12:20 12:20 – 13:00	Chairpersons: Professor JSM Peiris, Microbiology Professor KY Yuen, Microbiology Emergency and Re-emergency of H5N1 Influenza Viruses in Poultry in Southeastern Asia Dr Y Guan, Microbiology More coronaviruses Professor KY Yuen, Microbiology Keynote Lecture V How do Coronaviruses identify and infect host cells? Professor Kathryn V Holmes University of Colorado Health Sciences Center, USA Keynote Lecture VI Human Immune Response to SARS-CoV and Functional Analysis of SARS S-antigen Professor Hongkui Deng Peking University, China
Afternoon Parallel Session
16:30 – 16:50 16:50 – 17:30 17:30 – 17:50 17:50 – 18:10	Chairpersons: Dr Y Guan, Microbiology Dr Steve CL Lin, Surgery Trimeric S Glycoprotein of SARS-CoV Induces High-titer Neutralising Antibodies that Block Virus Binding to the ACE2 Receptor Professor Ralf Altmeyer, HKU-Pasteur Research Centre Keynote Lecture XIV How iron regulates virulence in Corynebacterium diphtheriae and Mycobacterium tuberculosis Professor Randall K Holmes University of Colorado Health Sciences Center, USA HIV-1 gp120 Binding to DC-SIGN Sensitises Dendritic Cells for Killing by Multiple Stimuli Dr Steve CL Lin, Surgery Mechanisms for HIV Subversion of Immune Response: Activation of the IL-10 Promoter and Gene Induction by Tat Dr Allan SY Lau, Paediatrics and Adolescent Medicine
4. Public Health: Joint Scientific Meeting of the Institute of Medical and Health Sciences Education (IMHSE) and School of Public Health
Morning Parallel Session
11:00 – 11:20 11:20 – 11:40 11:40 – 12:00 12:00 – 12:40 12:40 – 13:00	Theme: The scholarship of education and learning: HKU’s experience Chairpersons: Professor Mary SM Ip, IMHSE Professor F Salili, Nursing Studies Integration of basic and clinical disciplines in medical education Dr Niv Patil, Institute of Medical and Health Sciences Education Status of research in medical education / The effectiveness of PBL in enhancing students’ critical thinking Professor LC Chan, Pathology / Dr Agnes FY Tiwari, Nursing Studies Theme: Tobacco or health: secondhand smoke, smoking cessation and behavioural modification Chairpersons: Dr Sarah McGhee, Community Medicine Dr Agnes FY Tiwari, Nursing Studies A Randomized Controlled Trial of a Nurse-delivered Smoking Cessation Intervention for Cardiac Patients in Hong Kong Dr Sophia SC Chan, Nursing Studies Keynote Lecture VII Tobacco and the future of public health Professor Karen M Emmons Dana-Faber Cancer Institute and Havard School of Public Health, USA The Cost of Secondhand Smoking in Hong Kong Dr Sarah McGhee, Community Medicine
Afternoon Parallel Session
16:30 – 16:50 16:50 – 17:30 17:30 – 17:50 17:50 – 18:10	Theme: Woman’s cancers: moving from gene-environment aetiologic research to disease prevention and interdisciplinary management Chairpersons: Dr Richard Fielding, Community Medicine Dr Cindy LK Lam, Medicine Psychosocial adjustment to breast cancer surgery: a prospective study Dr Wendy WT Lam, Nursing Studies Keynote Lecture XV Breast cancer etiology: Diet, hormones, and genes Professor Wei Zheng Vanderbilt University Medical Center, USA The Combat of Mid-aged Chinese Australians against Advanced Cancer: The Impact of the Chinese Culture Dr Caroline YY Chui, Nursing Studies Cost-effectiveness of screening for women’s cancers Dr Gabriel M Leung, Community Medicine
5. Reproduction and Development: Joint Scientific Meeting of the Centre of Human Development & Birth Defects and Centre of Human Reproduction
Morning Parallel Session
11:00 – 11:40 11:40 – 12:00 12:00 – 12:20 12:20 – 13:00	Chairpersons: Dr WS O, Anatomy Professor Pak Sham, Psychiatry Keynote Lecture VIII Digital differential display - a powerful tool to define molecular signature Professor Shinya Yamanaka Nara Institute of Science and Technology, Japan Genetic analysis of the role of procollagen IIA as an extracellular regulator of BMP signaling Professor Kathryn SE Cheah, Biochemistry The Tails of the Transgelin Family Dr Janet CL Zhang, Medicine Keynote Lecture IX Neural crest induction during development Professor Marianne Bronner-Fraser California Institute of Technology, USA
Afternoon Parallel Session
16:30 – 16:50 16:50 – 17:10 17:10 – 17:30 17:30 – 18:10	Chairpersons: Professor LC Chan, Pathology Dr William SB Yeung, Obstetrics & Gynaecology Neuron differentiation in mouse ES cells containing a single human chromosome 21: an in vitro model of neurogenesis in Down's syndrome Professor Chi Chiu Wang Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong Interaction of the embryo with the oviduct Dr William SB Yeung, Obstetrics & Gynaecology Postnatal support to new mothers Dr Sharon SK Leung, Nursing Studies Keynote Lecture XVI Human reproduction and oxidative stress Professor Eric Jauniaux Royal Free & University College London, UK