Research Projects
TSPYL Target Genes in Cancer Pathways

Programme(s) to which this project applies:

☑ MPhil/PhD ☒ MRes[Med] ☒ URIS
About the Project

TSPYL proteins contain a highly conserved nucleosome assembly protein domain but their biological importance is largely unknown. Our group has been elucidating their functions both in vitro and in vivo. We have been using gene knockout and gene knockdown and the data suggest that TSPYL genes are important tumour suppressors. To address the mechanisms involved, we shall find out how TSPYL proteins regulate gene expression during development and tumour growth.

About the Supervisor

Dr SY Chan, Department of Paediatrics and Adolescent Medicine


Next Step?

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website.

General admission enquiries should be directed to