Research Projects
The Impact of the Hong Kong AMR Action Plan on the Prevalence of Anti-Microbial Resistance in the Community


Programme(s) to which this project applies:

☒ MPhil/PhD ☑ MRes[Med] ☒ URIS
About the Project

Objective and Significance:

Over the past two decades, humans are losing the upper hand in the fight against microbes because antibiotics, and other antimicrobial drugs, are losing their ability to kill bacteria due to the development of antimicrobial resistance (AMR). Hong Kong as a city is highly vulnerable to AMR resistance. In 2017, the Hong Kong SAR government addressed the Hong Kong Strategy and Action Plan on Antimicrobial Resistance Action Plan (2017-22) and committed both important financial and political resources to this endeavor. Among the goal of the HK Action Plan is to reduce the prevalence of AMR the community through 18 specific objectives. The overall objective of this research project is to evaluate the short-run impact of the introduction of the HK AMR action plan on the prevalence of reported cases of AMR at health facilities in Hong Kong.

Research Plan and Methodology:

The study will be a retrospective observational study of the prevalence of AMR in health facilities in Hong Kong. The project will utilize interrupted time series (ITS), one of the strongest quasiexperimental designs, to assess the early impact of the introduction of the plan in 2018 on indicators of the prevalence of amicrobial resistance The specific outcome variables we will investigate, as well as their data source, are:

  • The number of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) cases using data collected through the HA.
  • The use of antimicrobials as collected through the electronic dispensing system.

The ITS will test to see if there is a change in the level and slope of trends in these outcomes, any significant effect can be attributed to the introduction of the Action plan. Qualitative data will also be collected via interviews with hospital managers in a small subset of facilities to understand the actual data of introduction of measures.

About the Supervisor

Dr KA Grépin, School of Public Health

Biography
kgrepin@hku.hk

Next Step?

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to rpgmed@hku.hk.

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.