Research Projects
Pathogenic Mechanisms of Genetic Skeletal Disorders

Programme(s) to which this project applies:

☑ MPhil/PhD ☑ MRes[Med] ☒ URIS

Skeletal disorder is a heterogeneous group of conditions associated with various abnormalities of the skeleton (e.g., bone, cartilage, tendon, and ligament), most of which are the results of genetic defects that disrupt the normal skeletal growth and development. There are more than 400 different skeletal disorders, which can present any time from the prenatal period to adult life. They occur in 1/5,000 births, and some are lethal. This project aims to investigate the genetic bases of some skeletal disorders (e.g., congenital scoliosis, adolescent idiopathic scoliosis, osteogenesis imperfecta) and understand their underlying pathogenic mechanisms using transgenic animal models (e.g., zebrafish or mouse).

Dr B Gao, School of Biomedical Sciences


For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.