Research Projects
Mindfulness Intervention for Relapse in Psychosis

Programme(s) to which this project applies:

☒ MPhil/PhD ☑ MRes[Med] ☒ URIS
About the Project

Objective and Significance:

The relapse rate is high in patients with psychosis. Even with maintenance medication treatment, relapse occurs in 40% of the recovered patients. The consequences of relapse including hospitalization and financial burden can be substantial. Unfortunately, some of these consequences can be irreversible and may lead to treatment refractory.

One key precipitating factor of psychotic relapse is stress. The exploration of nonpharmacological intervention that modulates stress, such as mindfulness intervention, may be key to relapse prevention in psychosis. Nowadays, practicing mindfulness is popular and well-accepted for its benefits in improving mental and physical health. In particular, its benefits in promoting resilience to stress and well-being have been shown in studies involving different psychiatric conditions, as well as preventing relapse in patients with depressive disorders. However, its role in relapse prevention among patients with psychosis has not been tested.

Through mindfulness (no equipment needed, not costing any money to practice, and can be practiced at any time and place convenient to patients), we hope to alter and provide patients with an alternative response in face of stressful situations, and thus reduce the risk of relapse in psychosis.

Research Plan and Methodology:

We propose a multi-site, single-blind, 12-month randomized controlled trial to examine the effectiveness of mindfulness intervention in prevention of relapse in remitted psychosis patients.

About the Supervisor

Dr CLM Hui, Department of Psychiatry


Next Step?

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.