Research Projects
Investigation of Neuroplasticity-Dependent and -Independent Mechanisms of Electrical Deep Brain Stimulation in Animal Models of Dementia and Depression

Programme(s) to which this project applies:

☒ MPhil/PhD ☑ MRes[Med] ☒ URIS
About the Project

Objective and Significance:

To investigate the role of neuroplasticity mechanisms of deep brain stimulation in animal models of dementia (Alzheimer’s disease and aging) and depression

Research Plan and Methodology:

  • Behavioral analysis of neuropsychiatric and cognitive functions in rodent models of dementia (Alzheimer’s disease and aging) and depression.
  • Gene expression and protein analysis of markers related to neuroplasticity function.
  • Immunohistochemistry
  • Microscopic quantification and morphological analysis of neurons and dendritic spines.
About the Supervisor

Dr LW Lim, School of Biomedical Sciences


Next Step?

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website. General admission enquiries should be directed to

HKUMed MBBS students interested in the Master of Research in Medicine (MRes[Med]) programme may visit the programme website for more information.  

HKUMed UG students interested in the Undergraduate Research Internship Scheme (URIS) may visit the scheme’s website for more information.