Programme(s) to which this project applies:
|☑ MPhil/PhD||☒ MRes[Med]||☑ URIS|
Diabetes is a world epidemic. It was estimated that 1 in 11 adults (9.1%, 463 million) suffered from diabetes in 2019 worldwide (IDF Diabetes Atlas, 9th edition) while 1 in 5 diabetics are >65 years old (136 million). This number will increase by 52% in 2045 (700 million). Meanwhile, diabetic neuropathy is a common complication of diabetes in the middle-aged working population. Lack of good methodology has made its diagnosis challenging.
Cornea is highly innervated by Adelta and unmyelinated C fibres, which are often affected in diabetic neuropathy. Non-invasive examination of corneal nerve sensitivity and morphometry may function as an early marker for diabetic neuropathy.
Dr ACY Lo, Department of Ophthalmology
Dr Amy Lo obtained her PhD from the Department of Neuroscience in Johns Hopkins University School of Medicine and joined the then newly established Eye Institute in Sep 2006. One of the PI’s research themes is neuroprotection in retinal ischemia/reperfusion using various mouse models. She has track record on understanding the pathogenesis of retinal ischemia from which several papers are published. She is well trained in rodent retinal phenotypic analyses.
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