Research Projects
Cell-Matrix Adhesion Stability and Microtubule Organisation


Programme(s) to which this project applies:

☑ MPhil/PhD ☒ MRes[Med] ☒ URIS
About the Project

The stability and turnover of integrin-mediated adhesion play an important role in tissue organisation, immune surveillance, and cancer invasive migration(metastasis). Integrins are adhesion receptors on the plasma membrane that act as the physical linkage between cells and extracellular matrices. Factors that regulate the molecular compositions of cell-matrix adhesion have the direct impact on the adhesion formation, conversion, and disassembly. In this research project, we aim to investigate the functional role of novel matrix cleavage and redistribution of microtubule organisation centre in adhesion stability and cell migration.

About the Supervisor

Dr CH Yu, School of Biomedical Sciences

My research team aims to decipher the molecular reorganisation and signal transduction at the cell-matrix adhesion. We provide four-year scholarship and are looking for one to two talented PhD students.

Biography
Laboratory Homepage
chyu1@hku.hk

Next Step?

For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description.  Interested candidates are advised to enclose with your email:

  1. your CV,
  2. a brief description of your research interest and experience, and
  3. two reference letters (not required for HKUMed UG students seeking MRes[Med]/URIS projects).

Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website.

General admission enquiries should be directed to rpgmed@hku.hk.