Programme(s) to which this project applies:
|☑ MPhil/PhD||☒ MRes[Med]||☒ URIS|
The laboratory of Dr Shih-Chieh Ti in the School of Biomedical Sciences at the University of Hong Kong seeks enthusiastic and self-motivated PhD students to investigate the underlying mechanism for human tubulin isotypes to regulate the biological functions of microtubules.
The human genome encodes multiple α- and β-tubulin gene families (i.e., isotypes) that have the protein expression profile varying with cell types and developmental stages. While single point mutations in a specific tubulin isotype have been associated with human diseases, the molecular mechanism by which tubulin isotypes confer microtubules’ functions remains poorly understood. Using our field-leading strategy to generate isotypically pure recombinant human tubulin, Ti Lab will employ combinatorial approaches of biochemistry, biophysics, chemical biology, and structural biology to investigate the intrinsic properties of different human tubulin isotypes. Please see the following references to learn more about Dr Ti’s previous work.
An ideal candidate should have excellent experiment and communication skills. Preference will be given to applicants with a strong background in molecular biology, protein purification, and cell culture.
For more information or to express interest for this project, please email the supervisor or the specified contact point in the project description. Interested candidates are advised to enclose with your email:
Information on the research programme, funding support and admission documentations could be referenced online at the Research Postgraduate Admissions website.
General admission enquiries should be directed to firstname.lastname@example.org.