Research > Publication Highlights
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
Gao B, Hu J, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L, Cheah KS, Chan D.
Nature. 2009 Apr 30;458(7242):1196-200. Epub 2009 Mar 1.
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FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.
Li SK, Smith DK, Leung WY, Cheung AM, Lam EW, Dimri GP, Yao KM.
J Biol Chem. 2008 Jun 13;283(24):16545-53. Epub 2008 Apr 11.
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Association of the asporin D14 allele with lumbar-disc degeneration in Asians.
Song YQ, Cheung KM, Ho DW, Poon SC, Chiba K, Kawaguchi Y, Hirose Y, Alini M, Grad S, Yee AF, Leong JC, Luk KD, Yip SP, Karppinen J, Cheah KS, Sham P, Ikegawa S, Chan D.Am J Hum Genet. 2008 Mar;82(3):744-7. Epub 2008 Feb 21.
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Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in mice
.Lui VC, Cheng WW, Leon TY, Lau DK, Garcia-Barcelo MM, Miao XP, Kam MK, So MT, Chen Y, Wall NA, Sham MH, Tam PK.
Gastroenterology. 2008 Apr;134(4):1104-15. Epub 2008 Jan 17. Erratum in:
Gastroenterology. 2008 Aug;135(2):713. Garcia-Bareclo, Maria-Mercedes [corrected to Garcia-Barcelo, Maria-Mercedes
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PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC. Am J Hum Genet. 2007 Sep;81(3):559-75. Epub 2007 Jul
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Intervertebral disc transplantation in the treatment of degenerative spine
disease: a preliminary study.
Ruan D, He Q, Ding Y, Hou L, Li J, Luk KD. Lancet.
2007 Mar 24;369(9566):993-9.
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Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function.
Tsang KY, Chan D, Cheslett D, Chan WC, So CL, Melhado IG, Chan TW, Kwan KM, Hunziker EB, Yamada Y, Bateman JF, Cheung KM, Cheah KS. PLoS Biol. 2007 Mar;5(3):e44
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Association of the Taq I allele in vitamin D receptor with degenerative disc disease and disc bulge in a Chinese population.
Cheung KM, Chan D, Karppinen J, Chen Y, Jim JJ, Yip SP, Ott J, Wong KK, Sham P, Luk KD, Cheah KS, Leong JC, Song YQ. Spine. 2006 May 1;31(10):1143-8.
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The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice.
Kong CT, Sham MH, So CW, Cheah KS, Chen SJ, Chan LC.
Leukemia (2006) 20, 1829–1839. doi:10.1038/sj.leu.2404342; published online 3 August 2006
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TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease.
Garcia-Barcelo M, Ganster RW, Lui VC, Leon TY, So MT, Lau AM, Fu M, Sham MH, Knight J, Zannini MS, Sham PC, Tam PK.Hum Mol Genet. 2005 Jan 15;14(2):191-204.
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