Publication



    Viral ecology and Evolution:


    2008 – May 2011


  1. Smith GJ, Vijaykrishna D, Bahl J, Lycett SJ, Worobey M, Pybus OG, Ma SK, Cheung CL, Raghwani J, Bhatt S, Peiris JS, Guan Y, Rambaut A. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature. 2009 Jun 25;459(7250):1122-5. (Impact factor: 34.5)
  2. Vijaykrishna D, Smith GDJ, Pybus OG, Zhu H, Bhatt S, Poon LLM, Riley S, Bahl J, Ma SK, Cheung CL, Perera RAPM, Chen H, Shortridge KF, Webby RJ, Webster RG, Guan Y, Peiris JSM. Long-term evolution and transmission dynamics of swine influenza A virus. Nature. 2011 May 26;473(7348):519-22. doi: 10.1038/nature10004 (Impact factor: 38.6)
  3. Vijaykrishna D, Poon LL, Zhu HC, Ma SK, Li OT, Cheung CL, Smith GJ, Peiris JS, Guan Y. Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science. 2010 Jun 18; 328(5985):1529. (Impact factor: 29.8)
  4. Smith GJ, Bahl J, Vijaykrishna D, Zhang J, Poon LL, Chen H, Webster RG, Peiris JS, Guan Y. Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A. 2009 Jul 14; 106(28): 11709-12. Epub 2009 Jul 13 (Impact factor: 9.4)
  5. Wong EH, Smith DK, Rabadan R, Peiris M, Poon LL. Codon usage bias and the evolution of influenza A viruses. BMC Evol Biol. 2010 Aug 19; 10(1):253. (Impact factor: 4.3)
  6. Bahl J, Vijaykrishna D, Holmes EC, Smith GJ, Guan Y. Gene flow and competitive exclusion of avian influenza A virus in natural reservoir hosts. Virology. 2009 Aug 1;390(2):289-97. Epub 2009 Jun 5. (Impact factor: 3.04)
  7. Huang K, Bahl J, Fan XH, Vijaykrishna D, Cheung CL, Webby RJ, Webster RG, Chen H, Smith GJ, Peiris JS, Guan Y. Establishment of an H6N2 influenza virus lineage in domestic ducks in southern China. J Virol. 2010 Jul; 84(14):6978-86. Epub 2010 May 12. (Impact factor: 5.2)
  8. Ellis TM, Dyrting KC, Wong CW, Chadwick B, Chan C, Chiang M, Li C, Li P, Smith GJ, Guan Y, Malik Peiris JS Analysis of H5N1 avian influenza infections from wild bird surveillance in Hong Kong from January 2006 to October 2007 Avian Pathol. 2009 Apr;38(2):107-19. (Impact factor: 1.7)
  9. Smith GJ, Vijaykrishna D, Ellis TM, Dyrting KC, Leung YH, Bahl J, Wong CW, Kai H, Chow MK, Duan L, Chan AS, Zhang LJ, Chen H, Luk GS, Peiris JS, Guan Y. Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008. Emerg Infect Dis. 2009 Mar;15(3):402-7. (Impact factor: 6.8)
  10. Cheung PP, Leung YH, Chow CK, Ng CF, Tsang CL, Wu YO, Ma SK, Sia SF, Guan Y, Peiris JS Identifying the species-origin of faecal droppings used for avian influenza virus surveillance in wild-birds. J Clin Virol. 2009 Sep; 46(1):90-93. Epub 2009 Jul 14 (Impact factor: 3.1)
  11. Vijaykrishna D, Bahl J, Riley S, Duan L, Zhang JX, Chen H, Peiris JS, Smith GJ, Guan Y. Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses. PLoS Pathog. 2008 Sep 26; 4(9): e1000161. (Impact factor: 8.98)
  12. Wang J, Vijaykrishna D, Duan L, Bahl J, Zhang JX, Webs8ter RG, Peiris JS, Chen H, Smith GJ, Guan Y. Identification of the progenitors of Indonesian and Vietnamese avian influenza A (H5N1) viruses from southern China. J Virol. 2008 Apr; 82(7):3405-14. (Impact factor: 5.2)
  13. Duan L, Bahl J, Smith GJ, Wang J, Vijaykrishna D, Zhang LJ, Zhang JX, Li KS, Fan XH, Cheung CL, Huang K, Poon LL, Shortridge KF, Webster RG, Peiris JS, Chen H, Guan Y. The development and genetic diversity of H5N1 influenza virus in China, 1996-2006. Virology. 2008 Oct 25; 380(2):243-54. (Impact factor: 3.04)
  14. Guan Y, Smith GLD, Webby R, Webster RG. Molecular epidemiology of avian influenza H5N1. Rev.sci.tech.Off.int. Epiz. 2009; 28: (1), 39-47. (Impact factor: 1.24)
  15. Chan MC, Chan RW, Yu WC, Ho CC, Yuen KM, Fong JH, Tang LL, Lai WW, Lo AC, Chui WH, Sihoe AD, Kwong DL, Wong DS, Tsao GS, Poon LL, Guan Y, Nicholls JM, Peiris JS. Tropism and innate host responses of the 2009 pandemic H1N1 influenza virus in ex vivo and in vitro cultures of human conjunctiva and respiratory tract. Am J Pathol. 2010 Apr; 176(4):1828-40. Epub 2010 Jan 28.PMID: 20110407 (Impact factor: 6.5)

    Jun 2011-2012


  16. Fan X, Zhu H, Zhou B, Smith DK, Chen X, Lam TT, Poon LL, Peiris M, Guan Y. Emergence and dissemination of a swine H3N2 reassortant influenza virus with 2009 pandemic H1N1 genes in pigs in China. J Virol. 2012 Feb;86(4):2375-8. Epub 2011 Dec 14. (Impact Factor: 5.4)
  17. Zhu H, Zhou B, Fan X, Lam TT, Wang J, Chen A, Chen X, Chen H, Webster RG, Webby R, Peiris JS, Smith DK, Guan Y. Novel reassortment of Eurasian Avian-like and pandemic/2009 influenza viruses in swine: infectious potential for humans. J Virol. 2011; 85: 10432-9. (Impact Factor: 5.4)
  18. Perera RA, Riley S, Ma SK, Zhu HC, Guan Y, Peiris JS. Seroconversion to pandemic (H1N1) 2009 virus and cross-reactive immunity to other swine influenza viruses. Emerg Infect Dis. 2011 Oct;17(10):1897-9. (Impact Factor: 6.2)
  19. Lam TT, Zhu H, Wang J, Smith DK, Holmes EC, Webster RG, Webby R, Peiris JM, Guan Y. Reassortment events among swine influenza A viruses in China: implications for the origin of the 2009 influenza pandemic. J Virol. 2011 Oct;85(19):10279-85. Epub 2011 Jul 27. (Impact Factor: 5.4)
  20. Zhu H, Webby R, Lam TT, Smith DK, Peiris JS, Guan Y. History of Swine Influenza Viruses in Asia. Curr Top Microbiol Immunol. 2013;370:57-68. (Impact Factor: 4.9)
  21. Huang K, Zhu H, Fan X, Wang J, Cheung CL, Duan L, Hong W, Liu Y, Li L, Smith DK, Chen H, Webster RG, Webby RJ, Peiris M, Guan Y. Establishment and lineage replacement of H6 influenza viruses in domestic ducks in southern China. J Virol. 2012 Jun;86(11):6075-83. Epub 2012 Mar 21. (Impact Factor: 5.4)
  22. Pepin KM, Wang J, Webb CT, Smith GJ, Poss M, Hudson PJ, Hong W, Zhu H, Riley S, Guan Y. Multiannual patterns of influenza A transmission in Chinese live bird market systems. Influenza Other Respi Viruses. 2012 Mar 27. doi:10.1111/j.1750-2659.2012.00354.x. (Impact Factor: 1.5)
  23. Bahl J, Nelson MI, Chan KH, Chen R, Vijaykrishna D, Halpin RA, Stockwell TB, Lin X, Wentworth DE, Ghedin E, Guan Y, Peiris JS, Riley S, Rambaut A, Holmes EC, Smith GJ. Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19359-64. (Impact Factor: 9.7)
  24. Lai AC, Wu WL, Lau SY, Guan Y, Chen H. Two-dimensional antigenic dendrogram and phylogenetic tree of avian influenza virus H5N1. FEMS Immunol Med Microbiol. 2012 Mar;64(2):205-11. (Impact Factor: 2.4)
  25. Trevennec K, Leger L, Lyazrhi F, Baudon E, Cheung CY, Roger F, Peiris M, Garcia JM. Transmission of pandemic influenza H1N1 (2009) in Vietnamese swine in 2009-2010. Influenza Other Respi Viruses. 2012 Sep;6(5):348-57. doi: 0.1111/j.1750-2659.2011.00324.x. Epub 2011 Dec 30. (Impact Factor: 4.2)
  26. Desvaux S, Garcia JM, Nguyen TD, Reid SA, Bui NA, Roger F, Fenwick S, Peiris JS, Ellis T. Evaluation of serological tests for H5N1 avian influenza on field samples from domestic poultry populations in Vietnam: consequences for surveillance. Vet Microbiol. 2012 May 4;156(3-4):277-84. Epub 2011 Nov 22. (Impact Factor: 3.3)

    2013


  27. Perera HK, Wickramasinghe G, Cheung CL, Nishiura H, Smith DK, Poon LL, Perera AK, Ma SK, Sunil-Chandra NP, Guan Y, Peiris JS. 2013. Swine influenza in Sri Lanka. Emerg Infect Dis 19(3):481-484. (Impact Factor: 5.99)
  28. Zhu H, Wang D, Kelvin DJ, Li L, Zheng Z, Yoon SW, Wong SS, Farooqui A, Wang J, Banner D, Chen R, Zheng R, Zhou J, Zhang Y, Hong W, Dong W, Cai Q, Roehrl MH, Huang SS, Kelvin AA, Yao T, Zhou B, Chen X, Leung GM, Poon LL, Webster RG, Webby RJ, Peiris JS, Guan Y, Shu Y. Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science. 2013 Jul 12;341(6142):183-6. doi: 10.1126/science.1239844. Epub 2013 May 23. (Impact Factor: 31.03)
  29. Lam TT-Y, Wang J, Shen Y, Zhou B, Duan L, Cheung C-L, Ma C, Lycett SJ, Leung CYH, Chen X, Li F, Hong W, Chai Y, Zhou L, Liang H, Ou Z, Liu Y, Farooqui, Kelvin DJ, Poon LLM, Smith DK, Pybus OG, Leung GM, Shu Y, Webster RG, Webby RJ, Peiris JSM, Rambaut A, Zhu H*, Guan Y. 2013. The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature 502(7470):241-244 (Impact Factor: 38.60)

    2014


  30. Lee CC, Zhu H, Huang PY, Peng L, Chang YC, Yip CH, Li YT, Cheung CL, Compans R, Yang C, Smith DK, Lam TT, King CC, Guan Y. Emergence and evolution of avian H5N2 influenza viruses in chickens in Taiwan. J Virol. 2014 May;88(10):5677-86. doi: 10.1128/JVI.00139-14. Epub 2014 Mar 12. PMID: 24623422 (Impact factor: 4.65)
  31. Liang H, Lam TT, Fan X, Chen X, Zeng Y, Zhou J, Duan L, Tse M, Chan CH, Li L, Leung TY, Yip CH, Cheung CL, Zhou B, Smith DK, Poon LL, Peiris M, Guan Y, Zhu H. Expansion of Genotypic Diversity and Establishment of 2009 H1N1 Pandemic-Origin Internal Genes in Pigs in China. J Virol. 2014 Sep 15;88(18):10864-74. doi: 10.1128/JVI.01327-14. Epub 2014 Jul 9. PubMed PMID: 25008935. (Impact Factor: 4.648 (2013))
  32. Baudon E, Poon LLM, Tung DD, Nga PT, Cowling BJ, Peyre M, Khong NV, Peiris M. Detection of novel reassortant influenza A (H3N2) and H1N1 2009 pandemic viruses in swine in Hanoi, Vietnam. Zoonoses and Public Health 2014 Nov 1. doi: 10.1111/zph.12164. PMID: 25363845.
  33. Perera HKK, Vijaykrishna D, Premarathna AG, Jayamaha CJS, Wickramasinghe G, Cheung CL, Yeung MF, Poon LLM, Perera AKC, Barr IG, Guan Y, Peiris M. Molecular Epidemiology of Influenza A(H1N1)pdm09 Virus among Humans and Swine, Sri Lanka. Emerg Infect Dis. 2014 Dec;20(12):2080-4. doi: 10.3201/eid2012.140842. PMID: 25417652 (Impact Factor: 7.327)
  34. Peiris M & Yen HL. Animal and human influenzas. Eds WB Karesh. One Health. Scientific & Technical Review 2014; 33 (2) August – in press. (Impact factor: 0.97 (2013))

    Innate immunity, pathogenesis, virus receptors and tropism:



    2008 – May 2011


  35. Zhang J., Z. Zheng, X. Fan, Y. Liu, J. Wang, Z. Zheng, R. Chen, P. Wang, W. Song, H. Chen and Y. Guan (2009). 2009 pandemic H1N1 influenza virus replicates in human lung tissues. J Infect Dis. 2010 May 15;201(10):1522-6. (Impact factor: 5.9)
  36. Chan MC, Chan RW, Yu WC, Ho CC, Chui WH, Lo CK, Yuen KM, Guan Y, Nicholls JM, Peiris JM. Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells. Respir Res. 2009 Oct 30;10(1):102. (Impact factor: 3.1)
  37. Chan RW, Yuen KM, Yu WC, Ho CC, Nicholls JM, Peiris JS, Chan MC. Influenza H5N1 and H1N1 virus replication and innate immune responses in bronchial epithelial cells are influenced by the state of differentiation. PLoS One. 2010 Jan 15;5(1):e8713. (Impact factor: 4.4)
  38. Ng YP, Lee SM, Cheung TK, Nicholls JM, Peiris JS, Ip NY. Avian influenza H5N1 virus induces cytopathy and proinflammatory cytokine responses in human astrocytic and neuronal cell lines. Neuroscience. 2010 Jul 14;168(3):613-23. Epub 2010 Apr 14. (Impact factor: 3.3)
  39. Nicholls JM, Lai JCC and Garcia JM. Investigating the interaction between influenza and sialic acid – making and breaking the link. Influenza Virus Sialidase - A Drug Discovery Target. Milestones in Drug Therapy 2012, pp 31-45
  40. Haselhorst T, Garcia JM, Islam T, Lai JC, Rose FJ, Nicholls JM, Peiris JS, von Itzstein M. Avian influenza H5-containing virus-like particles (VLPs): host-cell receptor specificity by STD NMR spectroscopy. Angew Chem Int Ed Engl. 2008;47(10):1910-2. (Impact factor: 10)
  41. Lai JC, Chan WW, Kien F, Nicholls JM, Peiris JS, Garcia JM. Formation of virus-like particles from human cell lines exclusively expressing influenza neuraminidase. J Gen Virol. 2010 Sep;91(Pt 9):2322-30. Epub 2010 May 26. (Impact factor: 3.3)
  42. Chan RW, Chan MC, Wong AC, Karamanska R, Dell A, Haslam SM, Sihoe AD, Chui WH, Triana-Baltzer G, Li Q, Peiris JS, Fang F, Nicholls JM. DAS181 Inhibits H5N1 Influenza virus Infection of Human Lung Tissues. Antimicrob Agents Chemother. 2009 Jul 13;53:3935-41. (Impact factor: 4.7)
  43. Triana-Baltzer GB, Babizki M, Chan MC, Wong AC, Aschenbrenner LM, Campbell ER, Li QX, Chan RW, Peiris JS, Nicholls JM, Fang F. DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis. J Antimicrob Chemother. 2010 Feb;65(2):275-84. (Impact factor: 4.3)
  44. Triana-Baltzer GB, Gubareva LV, Nicholls JM, Pearce MB, Mishin VP, Belser JA, Chen LM, Chan RW, Chan MC, Hedlund M, Larson JL, Moss RB, Katz JM, Tumpey TM, Fang F. Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein. PLoS One. 2009 Nov 6;4(11):e7788. (Impact Factor 4.4)
  45. Lee SMY, Gardy JL, Cheung CY, Cheung TKW, Hui KPY, Ip NY, Guan Y, Hancock REW, Peiris JSM. Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages. PLoS One. 2009 Dec 14;4(12):e8072. (Impact factor: 4.4)
  46. Yu WC, Chan RW, Wang J, Travanty EA, Nicholls JM, Peiris JS, Mason RJ, Chan MC. Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with influenza H5N1 and H1N1 viruses. J Virol. 2011 May 4. [Epub ahead of print].(Impact Factor: 4.65)
  47. Lee SM, Chan RW, Gardy JL, Lo CK, Sihoe AD, Kang SS, Cheung TK, Guan Y, Chan MC, Hancock RE, Peiris JM. Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro. Respir Res. 2010 Oct 28;11(1):147. [Epub ahead of print] (Impact factor: 3.1)
  48. Hui KP, Lee SM, Cheung CY, Ng IH, Poon LL, Guan Y, Ip NY, Lau AS, Peiris JS. Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK. J Immunol. 2009 Jan 15;182(2):1088-98. (Impact factor: 5.6)
  49. Mok KP, Wong CH, Cheung CY, Chan MC, Lee SM, Nicholls JM, Guan Y, Peiris JS. Viral genetic determinants of H5N1 influenza viruses that contribute to cytokine dysregulation. J Infect Dis. 2009 Oct 1;200(7):1104-12. (Impact factor: 5.9)
  50. Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN. Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling. PLoS One. 2010 Nov 10;5(11):e13927. (Impact factor 4.4)
  51. Law AH, Lee DC, Yuen KY, Peiris M, Lau AS.Cellular response to influenza virus infection: a potential role for autophagy in CXCL10 and interferon-alpha induction. Cell Mol Immunol. 2010 Jul;7(4):263-70. Epub 2010 May 17. (Impact factor: 2.8)
  52. Mao H, Tu W, Liu Y, Qin G, Zheng J, Chan PL, Lam KT, Peiris JS, Lau YL. Inhibition of human natural killer cell activity by influenza virion and hemagglutinin. J Virol. 2010 Feb 17. (Impact factor: 5.2)
  53. Mao H, Tu W, Qin G, Law HK, Sia SF, Chan PL, Liu Y, Lam KT, Zheng J, Peiris M, Lau YL. Influenza virus directly infects human natural killer cells and induces cell apoptosis. J Virol. 2009 Jul 8. (Impact factor: 5.2)
  54. Chong WP, Zhou J, Law HK, Tu W, Lau YL. Natural killer cells become tolerogenic after interaction with apoptotic cells. Eur J Immunol. 2010 Jun;40(6):1718-27. (Impact factor: 5.2)
  55. Qin G, Mao H, Zheng J, Sia SF, Liu Y, Chan PL, Lam KT, Peiris JS, Lau YL, Tu W. Phosphoantigen-expanded human gammadelta T cells display potent cytotoxicity against monocyte-derived macrophages infected with human and avian influenza viruses. J Infect Dis. 2009 Sep 15;200(6):858-65. (Impact factor: 5.9)
  56. Tu W, Mao H, Zheng J, Liu Y, Chiu SS, Qin G, Chan PL, Lam KT, Guan J, Zhang L, Guan Y, Yuen KY, Peiris JS, Lau YL. Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus. J Virol. 2010 Jul;84(13):6527-35. Epub 2010 Apr 21. (Impact factor: 5.2)
  57. Zheng J, Liu Y, Lau YL and Tu W. CD40-activated B cells are more potent than immature dendritic cells to induce regulatory T cells. Cell Mol Immunol. 2010 Jan;7(1):44-50. (Impact factor: 2.8)
  58. Zheng J, Liu Y, Qin G, Lam KT, Guan J, Xiang Z, Lewis DB, Lau YL, Tu W. Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway. Eur J Immunol. 2011 Jan;41(1):128-39. doi: 10.1002/eji.201040724. (Impact Factor: 5.2)

    Jun 2011 – 2012



  59. Chan RW, Kang SS, Yen HL, Li AC, Tang LL, Yu WC, Yuen KM, Chan IW, Wong DD, Lai WW, Kwong DL, Sihoe AD, Poon LL, Guan Y, Nicholls JM, Peiris JS, Chan MC. Tissue tropism of swine influenza viruses and reassortants in ex vivo cultures of the human respiratory tract and conjunctiva. J Virol. 2011 Nov;85(22):11581-7. Epub 2011 Aug 31. (Impact Factor: 5.4)
  60. Yen H-L, Liang CH, Wu CY, Forrest H, Ferguson A, Choy KT, Jones J, Wong DDY, Cheung PPH, Hsu C-H, Li OT, Yuen KM, Chan RWY, Poon LLM, Chan MCW, Nicholls J, Krauss S, Wong C-H, Guan Y, Webster RG, Webby RJ, Peiris JSM. Hemagglutinin-neuraminidase balance confers respiratory droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14264-9. Epub 2011 Aug 8. (Impact Factor: 9.7)
  61. Lai JC, Garcia JM, Dyason JC, Böhm R, Madge PD, Rose FJ, Nicholls JM, Peiris JS, Haselhorst T, von Itzstein M. A secondary sialic acid binding site on influenza virus neuraminidase: fact or fiction? Angew Chem Int Ed Engl. 2012 Feb 27;51(9):2221-4. doi: 10.1002/anie.201108245. Epub 2012 Jan 26. (Impact Factor: 13.5)
  62. Leung HS, Li OT, Chan RW, Chan MC, Nicholls JM, Poon LL. Entry of influenza A Virus with a α2,6-linked sialic acid binding preference requires host fibronectin. J Virol. 2012 Oct;86(19):10704-13. doi: 10.1128/JVI.01166-12. Epub 2012 Jul 25 (Impact Factor: 5.4)
  63. Cheung CY, Chan EY, Krasnoselsky A, Purdy D, Navare AT, Bryan JT, Leung CK, Hui KP, Peiris JS, Katze MG. H5N1 virus causes significant perturbations in host proteome very early in influenza virus-infected primary human monocyte-derived macrophages. J Infect Dis. 2012 Sep 1;206(5):640-5. doi: 10.1093/infdis/jis423. Epub 2012 Jul 20. (Impact Factor: 6.4)
  64. Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW, Chan MC, Tu W, Guan Y, Lau YL, Peiris JS. H5N1 Influenza Virus-Induced Mediators Upregulate RIG-I in Uninfected Cells by Paracrine Effects Contributing to Amplified Cytokine Cascades. Journal of Infectious Diseases. 2011; 204(12):1866-78 (Impact Factor: 6.4)
  65. Qin G, Liu Y, Zheng J, Ng IH, Xiang Z, Lam KT, Mao H, Li H, Peiris JS, Lau YL, Tu W. Type 1 responses of human Vγ9Vδ2 T cells to influenza A viruses. J Virol. 2011. Oct;85(19):10109-16. Epub 2011 Jul 13. (Impact Factor: 5.4)
  66. Qin G, Liu Y, Zheng J, Xiang Z, Ng IH, Malik Peiris JS, Lau YL, Tu W. Phenotypic and functional characterization of human γδ T-cell subsets in response to influenza A viruses. J Infect Dis. 2012 Jun;205(11):1646-53. Epub 2012 Mar 28. (Impact Factor: 6.4)
  67. Zheng J, Liu Y, Lau YL and Tu W. Gammadelta-T Cells: unpolished sword in human antiviral Immunity. Cellular and Molecular Immunology, 2012 Oct 15. doi: 10.1038/ cmi.2012.43. [Epub ahead of print] (Impact Factor: 3.0)
  68. Ling MT, Tu W, Han Y, Mao H, Chong WP, Guan J, Liu M, Lam KT, Law HK, Peiris JS, Takahashi K, Lau YL. Mannose-binding lectin contributes to deleterious inflammatory response in pandemic H1N1 and avian H9N2 infection. J Infect Dis. 2012 Jan 1;205(1):44-53. Epub 2011 Nov 11. (Impact Factor: 6.4)
  69. Ma H, Kien F, Manière M, Zhang Y, Lagarde N, Tse KS, Poon LL, Nal B. Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection. J Virol. 2012 Feb;86(3):1789-801. Epub 2011 Nov 23. (Impact Factor: 5.4)
  70. Mok BW, Song W, Wang P, Tai H, Chen Y, Zheng M, Wen X, Lau SY, Wu WL, Matsumoto K, Yuen KY, Chen H* (2012). The NS1 protein of influenza A virus interacts with cellular processing bodies (P-bodies) and stress granules through RNA-associated protein 55 (RAP55) during virus infection. J. Virol. 2012, 86(23):12695-12707 (Impact Factor: 5.4)
  71. Mok CK, Yen HL, Yu MY, Yuen KM, Sia SF, Chan MC, Qin G, Tu WW, Peiris JS. Amino acid residues 253 and 591 of the PB2 protein of avian influenza virus A H9N2 contribute to mammalian pathogenesis. J Virol. 2011 Sep;85(18):9641-5. Epub 2011 Jul 6. (Impact Factor: 5.4)
  72. Greenbaum BD, Li OT, Poon LL, Levine AJ, Rabadan R. Viral reassortment as an information exchange between viral segments. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3341-6. Epub 2012 Feb 13. (Impact Factor: 9.7)
  73. Yu WC, Chan RW, Wang J, Travanty EA, Nicholls JM, Peiris JS, Mason RJ, Chan MC. Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with influenza H5N1 and H1N1 viruses. J Virol. 2011 Jul;85(14):6844-55. (Impact Factor: 5.4)
  74. Liu Y, Wu Y, Lam KT, Lee PP, Tu W, Lau YL. Dendritic and T cell response to influenza is normal in the patients with X-linked agammaglobulinemia. J Clin Immunol. 2012 Jun;32(3):421-9 (Impact Factor: 3.1)
  75. Wu Y, Mao H, Ling MT, Chow KH, Ho PL, Tu W, Lau YL. Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function. BMC Infect Dis. 2011 Jul 20;11:201. (Impact Factor: 3.1)
  76. Tang DJ, Lam YM, Siu YL, Lam CH, Chu SL, Peiris JS, Buchy P, Nal B, Bruzzone R. A Single Residue Substitution in the Receptor-Binding Domain of H5N1 Hemagglutinin Is Critical for Packaging into Pseudotyped Lentiviral Particles. PLoS One. 2012;7(11):e43596. doi: 10.1371/journal.pone.0043596. (Impact Factor: 4.1)
  77. Mao H, Yang W, Lee PPW, Ho MHK, Yang J, Zeng S, Chong CY, Lee TL, Tu W, Lau YL. Exome Sequencing Identifies Novel Compound Heterozygous Mutations in Interleukin-10 Receptor A in a Neonatal-Onset Crohn’s Disease. Genes and Immunity 2012 April 5; doi:10.1038/gene.2012.8 [Epub ahead of print] (Impact Factor: 3.9)

    2013


  78. Walther T, Karamanska R, Chan RW, Chan MC, Jia N, Air G, Hopton C, Wong MP, Dell A, Malik Peiris JS, Haslam SM, Nicholls JM. Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS Pathog. 2013 Mar;9(3):e1003223. doi: 10.1371/journal.ppat.1003223. (Impact Factor: 8.14 )
  79. Chan RW, Karamanska R, Van Poucke S, Van Reeth K, Chan IW, Chan MC, Dell A, Peiris JS, Haslam SM, Guan Y, Nicholls JM. Infection of swine ex vivo tissues with avian viruses including H7N9 and correlation with glycomic analysis. Influenza Other Respi Viruses. 2013 Aug 27. doi: 10.1111/irv.12144. (Impact Factor: 1.47)
  80. Li H, Xiang Z, Feng T, Li J, Liu Y, Fan Y, Lu Q, Yin Z, Yu M, Shen C, Tu W. Human Vγ9Vδ2-T cells efficiently kill influenza virus-infected lung alveolar epithelial cells. Cell Mol Immunol. 2013 Mar;10(2):159-64. doi: 10.1038/cmi.2012.70. (Impact Factor: 3.42)
  81. Li J, Li H, Mao H, Yu M, Feng T, Yang F, Fan Y, Lu Q, Shen C, Yin Z, Tu W, Mao M. Vγ9Vδ2-T lymphocytes have impaired antiviral function in small-for-gestational-age and preterm neonates. Cell Mol Immunol. 2013 May;10(3):253-60. doi: 10.1038/cmi.2012.78. (Impact Factor: 3.42)
  82. Li J, Li H, Mao H, Yu M, Yang F, Feng T, Fan Y, Lu Q, Shen C, Yin Z, Mao M, Tu W. Impaired NK cell antiviral cytokine response against influenza virus in small-for-gestational-age neonates. Cell Mol Immunol. 2013 Sep;10(5):437-43. doi: 10.1038/cmi.2013.31. (Impact Factor: 3.42)
  83. Zheng J, Liu Y, Liu Y, Liu M, Xiang Z, Lam KT, Lewis DB, Lau YL, Tu W. Human CD8+ regulatory T cells inhibit GVHD and preserve general immunity in humanized mice. Sci Transl Med. 2013 Jan 16;5(168):168ra9. doi: 10.1126/scitranslmed.3004943. (Impact Factor: 10.76)
  84. Chan PL, Zheng J, Liu Y, Lam KT, Xiang Z, Mao H, Liu Y, Qin G, Lau YL, Tu W. TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells. PLoS One. 2013 Jul 3;8(7):e67969. doi: 10.1371/journal.pone.0067969. Print 2013. (Impact Factor: 3.73)
  85. Chan, MCW; Chan, WY; CHAN, LY; Mok, KP; Hui, PY; Fong, JHM; Tao, KP; Poon, LLM; Nicholls, JM; Guan, Y. Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract. The Lancet Resp Dis. 2013; 1: 534-43 (Impact Factor pending)
  86. Chan RW, Chan MC, Nicholls JM, Malik Peiris JS. Use of ex vivo and in vitro cultures of the human respiratory tract to study the tropism and host responses of highly pathogenic avian influenza A (H5N1) and other influenza viruses. Virus Res. 2013 May 15. pii: S0168-1702(13)00078-6. doi: 10.1016/j.virusres.2013.03.003. (Impact Factor: 2.75 )

    2014


  87. Han Y, Ling MT, Mao H, Zheng J, Liu M, Lam KT, Liu Y, Tu W, Lau YL. Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice. PLoS One. 2014 Jan 21;9(1):e86166. doi: 10.1371/journal.pone.0086166. eCollection 2014. (Impact Factor: 3.73 (2012))
  88. Lee SM, Kok KH, Jaume M, Cheung TK, Yip TF, Lai JC, Guan Y, Webster RG, Jin DY, Peiris JS. Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3793-8. doi: 10.1073/pnas.1324266111. Epub 2014 Feb 24. (Impact Factor: 9.74 (2012))
  89. Tang JW, Gao CX, Cowling BJ, Koh GC, Chu D, Heilbronn C, Lloyd B, Pantelic J, Nicolle AD, Klettner CA, Peiris JS, Sekhar C, Cheong DK, Tham KW, Koay ES, Tsui W, Kwong A, Chan K, Li Y. Absence of Detectable Influenza RNA Transmitted via Aerosol during Various Human Respiratory Activities - Experiments from Singapore and Hong Kong. PLoS One. 2014 Sep 10;9(9):e107338. doi: 10.1371/journal.pone.0107338. eCollection 2014. PubMed PMID: 25208000; PubMed Central PMCID: PMC4160257. (Impact Factor: 3.53 (2013))
  90. Jia N, Barclay WS, Roberts K, Yen HL, Chan RW, Lam AK, Air G, Peiris JM, Dell A, Nicholls JM, Haslam SM. Glycomic characterisation of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies. J Biol Chem. 2014 Aug 18. pii: jbc.M114.588541. [Epub ahead of print] (Impact Factor: 4.6 (2013))
  91. Cheung PP, Watson SJ, Choy KT, Fun Sia S, Wong DD, Poon LL, et al. Generation and characterization of influenza A viruses with altered polymerase fidelity. Nat Commun. 2014;5:4794. PubMed PMID: 25183443; PubMed Central PMCID: PMC4155405. (Impact Factor: 10.74 (2013))
  92. Leung YH, Nicholls JM, Ho CK, Sia SF, Mok CK, Valkenburg SA, Cheung P, Hui KP, Chan RW, Guan Y, Akira S, Peiris JS. Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice. J Gen Virol. 2014 Sep;95(Pt 9):1870-9. doi: 10.1099/vir.0.066258-0. Epub 2014 May 30. PubMed PMID: 24878639; PubMed Central PMCID: PMC4135086. (Impact Factor: 3.529 (2013))
  93. Chin AW, Mok CK, Zhu H, Guan Y, Peiris JS, Poon LL. Use of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes. Influenza Other Respir Viruses. 2014 Sep;8(5):580-4. PubMed PMID: 25043276; PubMed Central PMCID: PMC4161617. (Impact Factor: 1.89 (2013)
  94. Xiang Z, Liu Y, Zheng J, Liu M, Lv A, Gao Y, Hu H, Lam KT, Chan GC, Yang Y, Chen H, Tsao GS, Bonneville M, Lau YL, Tu W. Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease. Cancer Cell. 2014 Sep 10. pii: S1535-6108(14)00314-6. doi: 10.1016/j.ccr.2014.07.026. [Epub ahead of print] PubMed PMID: 25220446. (Impact Factor: 23.9 (2013)
  95. Garcia JM, Lai JC, Haselhorst T, Choy KT, Yen HL, Peiris JS, von Itzstein M, Nicholls JM. Investigation of the binding and cleavage characteristics of N1 neuraminidases from avian, seasonal, and pandemic influenza viruses using saturation transfer difference nuclear magnetic resonance. Influenza Other Respir Viruses. 2014 Mar;8(2):235-42. doi: 10.1111/irv.12184. Epub 2013 Sep 30. PMID: 24118862 (Impact factor: 1.89 (2013))
  96. Zheng J, Chan PL, Liu Y, Qin G, Xiang Z, Lam KT, Lewis DB, Lau YL, Tu W. ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner. PLoS One. 2013 Dec 2;8(12):e82203. doi: 10.1371/journal.pone.0082203. eCollection 2013. PubMed PMID: 24312642; PubMed Central PMCID: PMC3846688. (Impact factor: 3.53 (2013))
  97. Liu H, Li X. Synthesis of cyclogentiotriose by macrocyclization via a ring-closing glycosylation. Tetrahedron Letters 55: (40): 5525-5528. doi:10.1016/j.tetlet.2014.08.063 (Impact factor: 2.39 (2013))
  98. Peng PL, H Liu, Gong JZ, Nicholls JM, Li XC. A facile synthesis of sialylated oligolactosamine glycans from lactose via the Lafont intermediate. Chemical Science 2014; 5 (9): 3634-3639 (Impact factor: 8.6 (2013))
  99. Liu H & Li XC. A Stereoselective Ring-Closing Glycosylation via Nonglycosylating Pathway. J Organic Chemistry 2014; 79 (12): 5834-41 PMID: 24877607

    Virology:



    2008 – May 2011


  100. Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL. Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation. PloS One. 2009 May 21;4(5):e5658. (Impact factor: 4.4)
  101. Liu N, Wang G, Lee KC, Guan Y, Chen H, Cai Z. Mutations in influenza virus replication and transcription: detection of amino acid substitutions in hemagglutinin of an avian influenza virus (H1N1). FASEB J. 2009 Jun 24 (Impact factor: 6.4)
  102. Wang P, Song W, Mok BW, Zhao P, Qin K, Lai A, Smith GJ, Zhang J, Lin T, Guan Y, Chen H. Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoprotein. J Virol. 2009 Aug;83(16):7850-61. Epub 2009 Jun 3. (Impact factor: 5.2)
  103. Zhu H, Wang J, Wang P, Song W, Zheng Z, Chen R, Guo K, Zhang T, Peiris JS, Chen H, Guan Y. Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice. Virology. 2010 May 25;401(1):1-5. Epub 2010 Mar 19. (Impact factor: 3.04)
  104. JL Umbach, H-L Yen, LLM Poon, BR Cullen. Influenza A virus expresses high levels of a novel class of small viral leader RNAs in infected cells. mBio 2010 Sep 14;1(4). pii: e00204-10. (Impact factor: 6.88 (2013))
  105. Liu N, W. Song, P. Wang, K-C Lee, Z. Cai1 and H. Chen (2010). Identification of Unusual Truncated Forms of Nucleocapsid Protein in MDCK Cells Infected by Avian Influenza Virus (H9N2). Proteomics, 2010 Mar 5. (Impact factor: 4.4)
  106. Ng SS, Li OT, Cheung TK, Malik Peiris JS, Poon LL. Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans. Virol J. 2008;5: 2. (Impact factor: 2.4)
  107. Li OT, Poon LL. DNA intercalator stimulates influenza transcription and virus replication. Virol J. 2011 Mar 15;8:120. (Impact Factor: 2.4)
  108. Teoh KT, Siu YL, Chan WL, Schlüter MA, Liu CJ, Peiris JS, Bruzzone R, Margolis B, Nal B. The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis. Mol Biol Cell. 2010 Sep 22. [Epub ahead of print] (Impact factor: 5.98)

    2013


  109. Chin AW, Greenbaum BD, Li OT, Webby RJ, Poon LL. A statistical strategy to identify recombinant viral ribonucleoprotein of avian, human, and swine influenza A viruses with elevated polymerase activity. Influenza Other Respi Viruses. 2013; 7: 969-78 (Impact Factor: 1.5)
  110. Li ZF, Liang YM, Lau PN, Shen W, Wang DK, Cheung WT, Xue CJ, Poon LM, Lam YW. Dynamic localisation of mature microRNAs in Human nucleoli is influenced by exogenous genetic materials. PLoS One. 2013 Aug 6;8(8):e70869. doi: 10.1371/journal.pone.0070869. (Impact Factor: 3.73)
  111. Mok CK, Lee HH, Chan MC, Sia SF, Lestra M, Nicholls JM, Zhu H, Guan Y, Peiris JM. Pathogenicity of the novel A/H7N9 influenza virus in mice. MBio. 2013 Jul 2;4(4). pii: e00362-13. doi: 10.1128/mBio.00362-13. (Impact Factor: 5.62 )
  112. Yen HL, McKimm-Breschkin JL, Choy KT, Wong DD, Cheung PP, Zhou J, Ng IH, Zhu H, Webby RJ, Guan Y, Webster RG, Peiris JS. Resistance to neuraminidase inhibitors conferred by an R292K mutation in a human influenza virus H7N9 isolate can be masked by a mixed R/K viral population. MBio. 2013 Jul 16;4(4). pii: e00396-13. doi: 10.1128/mBio.00396-13. (Impact Factor: 5.62 )

    2014


  113. Mok CK, Lee HH, Lestra M, Nicholls JM, Chan MC, Sia SF, Zhu H, Poon LL, Guan Y, Peiris JS. Amino acid substitutions in polymerase basic protein 2 gene contribute to the pathogenicity of the novel A/H7N9 influenza virus in mammalian hosts. J Virol. 2014 Mar;88(6):3568-76. doi: 10.1128/JVI.02740-13. Epub 2014 Jan 8. (Impact Factor: 5.08 (2012))
  114. Wen X, Huang X, Mok BW, Chen Y, Zheng M, Lau SY, Wang P, Song W, Jin DY, Yuen KY, Chen H. NF90 exerts antiviral activity through regulation of PKR phosphorylation and stress granules in infected cells. J Immunol. 2014 Apr 15;192(8):3753-64. doi: 10.4049/jimmunol.1302813. Epub 2014 Mar 12. PMID: 24623135 (Impact factor: 5.36 (2013))
  115. Song W, Wang P, Mok B W-Y, Lau S-Y Lau, Huang X, Wu W-L, Zheng M, Wen X , Yang S, Chen Y, Li L, Yuen KY, Chen H. K526R substitution in viral protein PB2 enhances the effects of E627K on influenza replication. 2014, Nature Communications, Accepted (Nat. Commun. 5:5509 doi: 10.1038/ncomms6509 (2014). PMID: 25409547 (Impact factor: 10.74 (2013))

    Diagnostic:


    2008 – May 2011


  116. Poon LL, Chan KH, Smith GJ, Leung CS, Guan Y, Yuen KY, Peiris JS Molecular detection of a novel human influenza (H1N1) of pandemic potential by conventional and real-time quantitative RT-PCR assays. Clin Chem. 2009 Aug;55(8):1555-8. Epub 2009 May 13. (Impact factor: 6.3)
  117. Lam WY, Leung TF, Lee N, Cheung JLK, Yeung ACM, Ho YII, Chan RCW, Fung KSC, Barr IG, Hui DSC, Sung JJY, Chan PKS. Development and comparison of molecular assays for the rapid detection of the pandemic influenza A (H1N1) 2009 virus. J Med Virol. 2010 Apr;82(4):675-83. (Impact factor: 2.5)
  118. Cheung TK, Chin AW, Chan KH, Schumaker M, Mak PW, Leung HS, Wong A, Peiris JS, Petrauskene OV, Poon LL. Evaluation of novel H1N1-specific primer-probe sets using commercial RT-PCR mixtures and a premixed reaction stored in a lyophilized format. J Virol Methods. 2010 Feb 6. (Impact factor: 2.1)
  119. Poon LL, Mak PW, Li OT, Chan KH, Cheung CL, Ma ES, Yen HL. Vijaykrishna D, Guan Y, Peiris JS. Rapid detection of reassortment of pandemic H1N1/2009 influenza virus. Clin Chem. 2010 Aug;56(8):1340-4. Epub 2010 Jun 21. (Impact factor: 6.3)
  120. Mak PW, Wong CK, Li OT, Chan KH, Cheung CL, Ma ES, Webby RJ, Guan Y, Malik Peiris JS, Poon LL. Rapid genotyping of Swine influenza viruses. Emerg Infect Dis. 2011 Apr;17(4):691-4. (Impact Factor: 6.8)
  121. Chan KH, Lai ST, Poon LL, Guan Y, Yuen KY, Peiris JS. Analytical sensitivity of rapid influenza antigen detection tests for swine-origin influenza virus (H1N1). J Clin Virol. 2009 Jul;45(3):205-7. Epub 2009 Jun 6. (Impact factor: 3.1)
  122. Cheng KYC, Cowling BJ, Chan KH, Fang VJ, Seto WH, Yung R, Uyeki TM, Houck PM, Peiris JSM, Leung GM. Factors affecting QuickVue Influenza A+B rapid test performance in the community setting. Diagnostic Microbiology and Infectious Disease, 2009: 65:35-41. (Impact factor: 2.5)
  123. Chan KH, Yam WC, Pang CM, Chan KM, Lam SY, Lo KF, Poon LL, Peiris JS. Comparison of the NucliSens easyMAG and Qiagen BioRobot 9604 nucleic acid extraction systems for detection of RNA and DNA respiratory viruses in nasopharyngeal aspirate samples. J Clin Microbiol. 2008 Jul;46(7):2195-9. Epub 2008 May 7. (Impact factor: 4.2)
  124. Ngai KLK, Wai-Yip Lam, Nelson Lee, Ting Fan Leung, David S.C. Hui, Chan PKS. Allele-SpecificQ1 Conventional Reverse-Transcription Polymerase Chain Reaction as a Screening Assay for Discriminating Influenza A HINI (H275Y) Oseltamivir-Resistant and Wild-Type Viruses, J of Medical Virology 2010; 82: 1295-8 (Impact factor: 2.5)
  125. Wang W, Ren P, Mardi S, Hou L, Tsai C, Chan KH, Cheng P, Sheng J, Buchy P, Sun B, Toyoda T, Lim W, Peiris JS, Zhou P, Deubel V Design of multiplexed detection assays for identification of avian influenza a virus subtypes pathogenic to humans by SmartCycler real-time reverse transcription-PCR. J Clin Microbiol. 2009 Jan;47(1):86-92. Epub 2008 Oct 29. (Impact factor: 4.2 )
  126. Garcia JM, Lagarde N, Ma ES, de Jong MD, Peiris JS. Optimization and evaluation of an influenza A (H5) pseudotyped lentiviral particle-based serological assay. J Clin Virol. 2010 Jan;47(1):29-33. Epub 2009 Nov 7. (Impact factor: 3.1)
  127. Buchy P, Vong S, Chu S, Garcia JM, Hien TT, Hien VM, Channa M, Ha do Q, Chau NV, Simmons C, Farrar JJ, Peiris M, de Jong MD. Kinetics of neutralizing antibodies in patients naturally infected by H5N1 virus. PLoS One. 2010 May 27;5(5):e10864. (Impact factor: 4.4)
  128. Schultsz C, Nguyen V, Le TH, Do QH, Peiris JSM, Lim W, Garcia JM, Nguyen DT, Nguyen THL, Huynh HT, Phan XT, van Doorn HR, Nguyen VC, Farrar J, de Jong, MD. Prevalence of Antibodies against Avian Influenza A (H5N1) Virus among Cullers and Poultry Workers in Ho Chi Minh City, 2005. PLOS ONE 2010; 4 (11): e7948. (Impact factor: 4.4 )
  129. Garcia JM, Pepin S, Lagarde N, Ma ESK, Vogel FR, Chan KH, Chiu SS, Peiris JSM. Heterosubtype Neutralizing Responses to Influenza A (H5N1) Viruses Are Mediated by Antibodies to Virus Haemagglutinin. PLoS One. 2009 Nov 20;4(11):e7918. (Impact factor: 4.4)

    Jun 2011 – 2012


  130. Tse M, Kim M, Chan CH, Ho PL, Ma SK, Guan Y, Peiris JSM. Evaluation of Three Commercially Available Influenza A Type-Specific Blocking Enzyme-Linked Immunosorbent Assays for Seroepidemiological Studies of Influenza A Virus Infection in Pigs. Clin Vaccine Immunol. 2012 March; 19(3): 334–337. (Impact Factor: 2.5)
  131. Nicholls JM, Wong LP, Chan RW, Poon LL, So LK, Yen HL, Fung K, van Poucke S, Peiris JS. Detection of highly pathogenic influenza and pandemic influenza virus in formalin fixed tissues by immunohistochemical methods. J Virol Methods. 2012 Feb;179(2):409-13. Epub 2011 Nov 18. (Impact Factor: 2.0)
  132. Chan KH, Chan KM, Ho YL, Lam YP, Tong HL, Poon LL, Cowling BJ, Peiris JS. Quantitative analysis of four rapid antigen assays for detection of pandemic H1N1 2009 compared with seasonal H1N1 and H3N2 influenza A viruses on nasopharyngeal aspirates from patients with influenza. J Virol Methods. 2012 Dec;186(1-2):184-8. (Impact Factor: 2.0)

    2013


  133. Wong CK, Zhu H, Li OT, Leung YH, Chan MC, Guan Y, Peiris JS, Poon LL. Molecular detection of human H7N9 influenza A virus causing outbreaks in China. Clin Chem. 2013 Jul;59(7):1062-7. Epub 2013 May 10. (Impact Factor: 7.15)

    2014


  134. Chan MC, Lee N, Ngai KL, Leung TF, Chan PK. Clinical and virologic factors associated with reduced sensitivity of rapid influenza diagnostic tests in hospitalized elderly patients and young children. J Clin Microbiol. 2014 Feb;52(2):497-501. doi: 10.1128/JCM.02316-13. Epub 2013 Nov 27. (Impact Factor: 4.07 (2012))
  135. Wong CK, Tsang GC, Chan KH, Li OT, Peiris M, Poon LL. A novel molecular test for influenza B virus detection and lineage differentiation. J Med Virol. 2014 Apr 24. PubMed PMID: 24760697. (Impact Factor: 2.22 (2013))

    Clinical:


    2008 – May 2011


  136. Chiu SS, Chan KH, Tu W, Lau YL, Peiris JS. Immunogenicity and safety of intradermal versus intramuscular route of influenza immunization in infants less than 6 months of age: a randomized controlled trial. Vaccine. 2009 Jul 30;27(35):4834-9. Epub 2009 Jun 11. (Impact factor: 3.6)
  137. Chiu SS, Chan KH, Chen H, Young BW, Lim W, Wong WHS, Lau YL, Peiris JSM. Virologically Confirmed Population-Based Burden of Hospitalization Caused by Influenza A and B among Children in Hong Kong. Clinical Infectious Diseases 2009;49:1016–1021 (Impact factor: 8.2)
  138. Chiu SS, Chan KH, Chen H, Young BW, Lim W, Wong WH, Peiris JS. Virologically Confirmed Population-Based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. Pediatr Infect Dis J. 2010 Jul 8. (Impact factor: 2.9)
  139. Chen H, X Wen, KKW To, P Wang, H Tse, JFW Chan, HW Tsoi, KSC Fung, C WS Tse, R A Lee, KH Chan, KY Yuen (2010). Quasi species of D225G substitution in hemagglutinin of pandemic influenza A (H1N1) 2009 virus from severe cases in Hong Kong of China. J. Infectious Diseases, 2010:201 (15 May) (Impact factor: 5.9)
  140. Chan PK, Lee N, Joynt GM, Choi KW, Cheung JL, Yeung AC, Lam P, Wong R, Leung BW, So HY, Lam WY, Hui DC. Clinical and virological course of infection with haemagglutinin D222G mutant strain of 2009 pandemic influenza A (H1N1) virus. J Clin Virol. 2011 Apr;50(4):320-4. (Impact Factor: 3.1)

    Jun 2011 – 2012


  141. Chiu SS, Chan KH, Wong WH, Chan EL, Peiris JS. Age-matched comparison of children hospitalized for 2009 pandemic H1N1 influenza with those hospitalized for seasonal H1N1 and H3N2. PLoS One. 2011;6(7):e21837. Epub 2011 Jul 20. (Impact Factor: 4.1)
  142. Chan PK, Chan MC, Cheung JL, Lee N, Leung TF, Yeung AC, Wong MC, Ngai KL, Nelson EA, Hui DS. Influenza B lineage circulation and hospitalisation rate in a subtropical city, Hong Kong, 2000-2010. Clinical Infectious Diseases. 2012 Oct 16. [Epub ahead of print] PMID:23074315. (Impact Factor: 9.2)
  143. Chiu SS, Chan KH, So LY, Chen R, Chan EL, Peiris JS. The population based socioeconomic burden of pediatric influenza-associated hospitalization in Hong Kong. Vaccine. 2012 Feb 27;30(10):1895-900. Epub 2012 Jan 2. (Impact Factor: 3.8)
  144. Chan MCW, Lee N, Ngai KLK, Wong BCK, Lee MKP, Choi KW, Lai RWM, Chan PKS. A “Pre-seasonal" Hospital Outbreak of Influenza Pneumonia Caused by the Drift Variant A/Victoria/361/2011-like H3N2 Viruses, Hong Kong, 2011. J Clin Virol. 2013 Mar;56(3):219-25. doi: 10.1016/j.jcv.2012.11.002. Epub 2012 Nov 30. (Impact Factor: 3.29)

    2013


  145. Chan MC, Lee N, Lui GC, Ngai KK, Wong RY, Choi KW, Chan PK. Comparisons of oseltamivir-resistant (H275Y) and concurrent oseltamivir-susceptible seasonal influenza A(H1N1) virus infections in hospitalized adults, 2008-2009. Influenza Other Respi Viruses. 2013 May;7(3):235-9. (Impact Factor: 1.5l)
  146. Chen Y, Liang W, Yang S, Wu N, Gao H, Sheng J, Yao H, Wo J, Fang Q, Cui D, Li Y, Yao X, Zhang Y, Wu H, Zheng S, Diao H, Xia S, Zhang Y, Chan KH, Tsoi HW, Teng JL, Song W, Wang P, Lau SY, Zheng M, Chan JF, To KK, Chen H, Li L, Yuen KY. Human infections with the emerging avian-origin influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. Lancet. 2013 Jun 1;381(9881):1916-25. doi: 10.1016/S0140-6736(13)60903-4. (Impact Factor: 39.06)
  147. Hu Y, Lu S, Song Z, Wang W, Hao P, Li J, Zhang X, Yen HL, Shi B, Li T, Guan W, Xu L, Liu Y, Wang S, Zhang X, Tian D, Zhu Z, He J, Huang K, Chen H, Zheng L, Li X, Ping J, Kang B, Xi X, Zha L, Li Y, Zhang Z, Peiris M, Yuan Z. Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet. 2013 Jun 29;381(9885):2273-9. doi: 10.1016/S0140-6736(13)61125-3. (Impact Factor: 39.06 )
  148. Yu L, Wang Z, Chen Y, Ding W, Jia H, Chan JF, To KK, Chen H, Yang Y, Liang W, Zheng S, Yao H, Yang S, Cao H, Dai X, Zhao H, Li J, Bao Q, Chen P, Hou X, Li L, Yuen KY. Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus. Clin Infect Dis. 2013 Nov;57(10):1449-57. doi: 10.1093/cid/cit541. (Impact Factor: 9.37)
  149. Zhang A, Y Huang, D Tian, Y Wan, X Liu, EHY Lau, Z Song, Y Dong, X Zhang, J Zhang, M Bao, M Zhou, S Yuan, J Sun, Z Zhu, Y Hu, L Chen, CYH Leung, X Zhang, JT Wu, Z Zhang, M Peiris, J Xu. Kinetics of the serological responses in influenza A/H7N9 infected patients correlate with clinical outcome in China, 2013 . Eurosurveillance – on line

    2014


  150. Yang S, Chen Y, Cui D, Yao H, Lou J, Huo Z, Xie G, Yu F, Zheng S, Yang Y, Zhu Y, Lu X, Liu X, Lau SY, Chan JF, To KK, Yuen KY, Chen H, Li L. Avian-origin influenza A(H7N9) infection in influenza A(H7N9)-affected areas of China: a serological study. J Infect Dis. 2014 Jan 15;209(2):265-9. doi: 10.1093/infdis/jit430. Epub 2013 Aug 9. (Impact Factor: 5.85 (2012))
  151. Chau SK, Lee SL, Peiris MJ, Chan KH, Chan E, Wong W, Chiu SS. Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection. Eur J Pediatr. 2014 Mar;173(3):291-301. doi: 10.1007/s00431-013-2127-z. Epub 2013 Aug 31. PubMed PMID: 23995960. (Impact factor: 1.98 (2013))

    Epidemiology and public health:



    2008 – May 2011


  152. Cowling BJ, Chan KH, Fang VJ, Cheng CK, Fung RO, Wai W, Sin J, Seto WH, Yung R, Chu DW, Chiu BC, Lee PW, Chiu MC, Lee HC, Uyeki TM, Houck PM, Peiris JS, Leung GM. Facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial. Ann Intern Med. 2009 Oct 6;151(7):437-46. Epub 2009 Aug 3. (Impact factor: 16.2)
  153. Cowling BJ, Fung RO, Cheng CK, Fang VJ, Chan KH, Seto WH, Yung R, Chiu B, Lee P, Uyeki TM, Houck PM, Peiris JS, Leung GM. Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households. PLoS ONE. 2008 May 7;3(5):e2101 (Impact factor: 4.4)
  154. Cowling BJ, Fang VJ, Riley S, Malik Peiris JS, Leung GM. Estimation of the Serial Interval of Influenza Epidemiology. 2009 May;20(3):344-7. (Impact factor: 5.5)
  155. Ng S, Cowling BJ, Fang VJ, Chan KH, Ip DKM, Cheng CKY, Uyeki TM, Houck PM, Peiris JSM, Leung GM. Effects of oseltamivir treatment on duration of clinical illness and viral shedding, and household transmission of influenza virus. Clinical Infectious Diseases, 2010; 50:707-14. (Impact factor: 8.2)
  156. Lau LLH, Cowling BJ, Fang VJ, Chan KH, Lau EHY, Lipsitch M, Cheng CKY, Houck PM, Uyeki TM, Peiris JSM, Leung GM. Viral shedding and clinical illness in naturally acquired influenza virus infections. Journal of Infectious Diseases, 2010; 201:1509-16. (Impact factor: 5.9)
  157. Cowling BJ, Chan KH, Fang VJ, Lau LLH, So THC, Fung ROP, Ma ESK, Kwong ASK, Chan CW, Tsui WWS, Ngai HY, Chu DWS, Lee PWY, Chiu MC, Leung GM,Peiris JSM. Comparative epidemiology of pandemic and seasonal influenza A in households. New England Journal of Medicine, 2010; 362:2175-84. (Impact factor: 47.05)
  158. Wu JT, Leung GM, Lipsitch M, Cooper BS, Riley S Hedging against antiviral resistance during the next influenza pandemic using small stockpiles of an alternative chemotherapy. PLoS Med. 2009 May 19;6(5):e1000085. Epub 2009 May 19. (Impact factor: 13.5)
  159. Wu JT, Lee CK, Cowling BJ, Yuen KY. Logistical feasibility and potential benefits of a population-wide passive-immunotherapy program during an influenza pandemic. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3269-74. Epub 2010 Feb 1. (Impact factor: 9.4)
  160. Wu JT, Cowling BJ, Lau EHY, Ip DKM, Ho LM, Tsang T, Chuang SK, Leung PY, Lo SV, Liu SH, Riley S. School Closure and Mitigation of Pandemic (H1N1) 2009, Hong Kong. Emerg Infect Dis 2010; 16: 538-41 (Impact factor: 6.8)
  161. Cowling BJ, Lau EH, Lam CL, Cheng CK, Kovar J, Chan KH, Peiris JS, Leung GM. Effects of school closures, 2008 winter influenza season, Hong Kong. Emerg Infect Dis. 2008 Oct;14(10):1660-2. (Impact factor: 6.8)
  162. Wu JT, Cowling BJ. The use of mathematical models to inform influenza pandemic preparedness and response. Exp Biol Med (Maywood). 2011 Aug;236(8):955-61. doi: 10.1258/ebm.2010.010271. Epub 2011 Jul 4. (Impact Factor: 2.8)
  163. Yang L, Wong CM, Chan KP, Chau PYK, Ou CQ, Chan KH, Peiris JSM. Seasonal effects of influenza on mortality in a subtropical city BMC Infect Dis. 2009 Aug 22; 9:133 (Impact factor: 2.6)
  164. Yang L, Chiu SS, Chan K-P, Chan K-H, Wong WH-S, et al. 2011 Validation of Statistical Models for Estimating Hospitalization Associated with Influenza and Other Respiratory Viruses. PLoS ONE 6(3): e17882. doi:10.1371/journal.pone.0017882 (Impact Factor: 4.3)
  165. Warren Gash C, Bhaskaran K, Hayward A, Leung GM, Lo SV, Pebody R, Smeeth L, Wong CM, Cowling BJ. Circulating influenza virus, climatic factors and acute myocardial infarction: a time series regression study in Hong Kong and the UK. J Infect Dis. 2011 Jun 15;203(12):1710-8. doi: 10.1093/infdis/jir171. (Impact Factor: 5.8)
  166. Cheng KYC, Lau EHY, Ip DKM, Yeung ASY, Ho LM, Cowling BJ. A profile of the online dissemination of national surveillance data. BMC Public Health, 2009; 9:339. (Impact factor: 2.2)
  167. Lau EH, Cowling BJ, Ho LM, Leung GM. Optimizing use of multistream influenza sentinel surveillance data. Emerg Infect Dis. 2008 Jul;14(7):1154-7. (Impact factor: 6.8)
  168. Cowling BJ, Ng S, Ma ESK, Cheng CKY, Wai W, Fang VJ, Chan KH, Ip DKM, Chiu SS, Peiris JSM, Leung GM. Protective efficacy of seasonal influenza vaccination against seasonal and pandemic influenza virus infection during 2009 in Hong Kong. Clinical Infectious Diseases, 2010; 51:1370-9. (Impact factor: 8.2)
  169. Wu JT, Ma ESK, Lee CK, Chu DKW, Ho PL, Shen AL, Ho A, Hung IFN, Riley S, Ho LM, Lin CK, Tsang T, Lo SV, Lau YL, Leung GM, Cowling BJ, Peiris JSM. The infection attack rate and severity of 2009 pandemic influenza (H1N1) in Hong Kong. Clin Infect Dis. 2010 Nov 15;51(10):1184-91. (Impact factor: 8.2)
  170. Riley S, Kwok KO, Wu KM, Ning DY, Cowling BJ, Wu JT, Ho LM, Tsang T, Lo SV, Chu DKW, Ma ESK, Peiris JSM. Epidemiological characteristics of 2009 pandemic influenza based on paired sera from a longitudinal community cohort study. PLoS Med. 2011 Jun;8(6):e1000442. doi: 10.1371/journal.pmed.1000442. Epub 2011 Jun 21. (Impact factor: 15.25)
  171. Chen H, Wang Y, Liu W, Zhang JX, Dong BQ, Fang XH, Jong MD, Farrar J, Riley R, Smith GJD, Guan Y (2009). Serologic survey of pandemic (H1N1) virus, Guangxi Province, China. Emerg Infect Dis. 2009 Nov;15(11):1849-50. (Impact factor: 6.8)
  172. Chen Y, Q Zheng, F Zeng, SY Lau, WL Wu, S Huang, J Zhang, H Chen and N Xia (2011). Serological survey of antibodies to influenza A viruses on a group of people without a history of influenza vaccination. Clin Microbiol Infect. 2011 Sep;17(9):1347-9. doi: 10.1111/j.1469-0691.2011.03538.x. Epub 2011 Jul 13 (Impact factor: 4.6)
  173. Zhou Y1, Ng DM, Seto WH, Ip DK, Kwok HK, Ma ES, Ng S, Lau LL, Wu JT, Peiris JS, Cowling BJ. Seroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kong. J Hosp Infect. 2011 Aug;78(4):308-11. doi: 10.1016/j.jhin.2011.02.017. Epub 2011 Apr 17. (Impact Factor: 2.9)
  174. Seto WH, Cowling BJ, Lam HS, Ching PTY, To ML, Pittet D. Clinical and Non-Clinical Healthcare Workers Faced a Similar Risk of Acquiring 2009 Pandemic H1N1 Infection. Clin Infect Dis. 2011 Aug 1;53(3):280-3. doi: 10.1093/cid/cir375. (Impact Factor: 9.37)
  175. Cowling BJ, Zhou Y, Ip DKM, Leung GM, Aiello AE. Face masks to prevent influenza transmission: a systematic review. Epidemiology and Infection, 2010; 138:449-56. (Impact factor: 2.4)
  176. Cowling BJ, Ng DMW, Ip DKM, Liao Q, Lam WWT, Wu JT, Lau JTF, Griffiths SM, Fielding R. Community psychological and behavioral responses through the first wave of 2009 pandemic (H1N1) in Hong Kong. Journal of Infectious Diseases, 2010; 202:867-76. (Impact factor: 5.9)
  177. Liao QY, Cowling BJ, Lam WT, Ng DMW, Fielding R. Situational Awareness and Health Protective Responses to Pandemic Influenza A (H1N1) in Hong Kong: A Cross-Sectional Study. PLoS ONE, 2010 Oct 12; 5(10): Art No. e13350 (Impact factor: 4.4)
  178. Liao Q, Cowling BJ, Lam WW, Fielding R. The influence of social-cognitive factors on personal hygiene practices to protect against influenzas: using modelling to compare avian A/H5N1 and 2009 pandemic A/H1N1 influenzas in Hong Kong. Int J Behav Med. 2011 Jun;18(2):93-104. (Impact factor: 0.9)
  179. Liao Q, Cowling BJ, Lam WWT, Fielding R, 2011 Factors Affecting Intention to Receive and Self-Reported Receipt of 2009 Pandemic (H1N1) Vaccine in Hong Kong: A Longitudinal Study. PLoS ONE 6(3): e17713. doi:10.1371/journal.pone.0017713 (Impact Factor: 4.3)
  180. Cowling BJ, Lau MSY, Ho LM, Chuang SK, Tsang T, Liu SH, Leung PY, Lo SV, Lau EHY. Prospective estimation of the effective reproduction number of pandemic influenza in Hong Kong. Epidemiology 2010 Nov;21(6):842-46. (Impact factor: 5.5)
  181. Cowling BJ, Lau LLH, Wu P, Wong HWC, Fang VJ, Riley S, Nishiura H. Entry screening to delay local transmission of pandemic influenza A (H1N1). BMC Infectious Diseases, 2010; 10:82. (Impact factor: 2.6)
  182. Nishiura H, Cook AR, Cowling BJ. Assortativity and the probability of epidemic extinction: A case study of pandemic influenza A (H1N1-2009). Interdisciplinary Perspectives on Infectious Diseases, 2011; 2011:194507. (Pending Impact Factor)
  183. Fabian P, McDevitt JJ, DeHaan WH, Fung RO, Cowling BJ, Chan KH, Leung GM, Milton DK. Influenza virus in human exhaled breath: an observational study. PLoS ONE. 2008 Jul 16;3(7):e2691 (Impact factor: 4.4)

    Jun 2011 – 2012


  184. Wu JT, Ho A, Ma ES, Lee CK, Chu DK, Ho PL, Hung IF, Ho LM, Lin CK, Tsang T, Lo SV, Lau YL, Leung GM, Cowling BJ, Peiris JS. Estimating infection attack rates and severity in real time during an influenza pandemic: analysis of serial cross-sectional serologic surveillance data. PLoS Med. 2011 Oct;8(10):e1001103. (Impact Factor: 16.3)
  185. Ejima K, Omori R, Cowling BJ, Aihara K, Nishiura H. The time required to estimate the case fatality ratio of influenza using only the tip of an iceberg: joint estimation of the virulence and the transmission potential. Comput Math Methods Med. 2012;2012:978901. Epub 2012 May 10. (Impact Factor: 0.7)
  186. Kelly H, Peck HA, Laurie KL, Wu P, Nishiura H, Cowling BJ. The age-specific cumulative incidence of infection with pandemic influenza H1N1 2009 was similar in various countries prior to vaccination. PLoS ONE, 2011; 6(8): e21828. (Impact Factor: 4.1)
  187. Van Kerkhove MD, Riley S, Lipsitch M, Guan Y, Monto AS, Webster RG, Zambon M, Nicoll A, Peiris JS, Ferguson NM. Comment on "Seroevidence for H5N1 influenza infections in humans: meta-analysis". Science. 2012 Jun 22;336(6088):1506; (Technical comment on paper, Grant acknowledgements not permitted). (Impact Factor: 31.2)
  188. Cowling BJ, Ng S, Ma ES, Fang VJ, So HC, Wai W, Cheng CK, Wong JY, Chan KH, Ip DK, Chiu SS, Peiris JS, Leung GM. Protective efficacy against pandemic influenza of seasonal influenza vaccination in children in Hong Kong: a randomized controlled trial. Clin Infect Dis. 2012 Sep; 55(5):695-702. Epub 2012 Jun 5. (Impact Factor: 9.2)
  189. Cowling BJ, Fang VJ, Nishiura H, Chan KH, Ng S, Ip DK, Chiu SS, Leung GM, Peiris JS. Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine. Clin Infect Dis. 2012 Jun;54(12):1778-83. Epub 2012 Mar 15. (Impact Factor: 9.2)
  190. Lau LLH, Nishiura H, Kelly H, Ip DKM, Leung GM, Cowling BJ. Household transmission of 2009 pandemic influenza A(H1N1): a systematic review and meta-analysis. Epidemiology, 2012; 23(4):531-42. (Impact Factor: 5.6)
  191. Klick B, Nishiura H, Ng S, Fang VJ, Leung GM, Peiris JSM, Cowling BJ. Transmissibility of seasonal and pandemic influenza in a cohort of households in Hong Kong in 2009. Epidemiology, 2011 Nov;22(6):793-6. (Impact Factor: 5.6)
  192. Poon LL, Chan KH, Chu DK, Fung CC, Cheng CK, Ip DK, Leung GM, Peiris JS, Cowling BJ. Viral genetic sequence variations in pandemic H1N1/2009 and seasonal H3N2 influenza viruses within an individual, a household and a community. J Clin Virol. 2011 Oct;52(2):146-50. Epub 2011 Jul 29. (Impact Factor: 4.0)
  193. Klick B, Nishiura H, Cowling BJ. Optimal design of intervention studies to prevent influenza in healthy cohorts. PLoS ONE, 2012; 7(4):e35166. (Impact Factor: 4.1)
  194. Ip DK, Schutten M, Fang VJ, Fung RO, Dutkowski RT, Chan KH, Leung GM, Peiris JS, Cowling BJ. Validation of self-swab for virologic confirmation of influenza virus infections in a community setting. J Infect Dis. 2012 Feb 15;205(4):631-4. Epub 2011 Dec 23. (Impact Factor: 6.4)
  195. Cowling BJ. Airborne transmission of influenza: implications for control in healthcare and community settings [Editorial]. Clinical Infectious Diseases, 2012; 54(11):1578-80. [IF 9.2 (2011), rank 2/70 infectious diseases] (Impact Factor: 9.2)
  196. Lau EHY, Cheng CKY, Ip DKM, Cowling BJ. Situational awareness of influenza activity based on multiple streams of surveillance data using multivariate dynamic linear model. PLoS ONE, 2012; 7(5): e38346. [IF 4.1 (2011), rank 12/84 biology] (Impact Factor: 4.1)
  197. Cheng CK, Ip DK, Cowling BJ, Ho LM, Leung GM, Lau EH. Digital dashboard design using multiple data streams for disease surveillance with influenza surveillance as an example. J Med Internet Res. 2011 Oct 14;13(4):e85. (Impact Factor: 4.4)
  198. Wang XL, Yang L, Chan KP, Chiu SS, Chan KH, Peiris JS, Wong CM. Model selection in time series studies of influenza-associated mortality. PLoS One. 2012;7(6):e39423. Epub 2012 Jun 20. (Impact Factor: 4.1)
  199. Yang L, Chan KP, Cowling BJ, Chiu SS, Chan KH, Peiris JS, Wong CM. Excess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong. Epidemiol Infect. 2012 Sep;140(9):1542-50. Epub 2011 Nov 11. (Impact Factor: 2.8)
  200. Yang L, Chen PY, He JF, Chan KP, Ou CQ, Deng AP, Malik Peiris JS, Wong CM. Effect modification of environmental factors on influenza-associated mortality: a time-series study in two Chinese cities. BMC Infect Dis. 2011 Dec 14;11:342. (Impact Factor: 3.1)
  201. Yang L, Wang XL, Chan KP, Cao PH, Lau EHY, Peiris JSM, Wong CM. Hospitalisation associated with the 2009 H1N1 pandemic and seasonal influenza in Hong Kong, 2005 to 2010. Euro Surveill. 2012;17(45):pii=20309 (Impact Factor: 6.2)
  202. Wong JY, Wu P, Nishiura H, Goldstein E, Lau EH, Yang L, Chuang SK, Tsang T, Peiris JS, Wu JT, Cowling BJ. Infection fatality risk of the pandemic A(H1N1)2009 virus in Hong Kong. Am J Epidemiol. 2013 Apr 15;177(8):834-40. doi: 10.1093/aje/kws314. Epub 2013 Mar 3. (Impact Factor: 4.8)
  203. Yang L, Ma S, Chen PY, He JF, Chan KP, Chow A, Ou CQ, Deng AP, Hedley AJ, Wong CM, Peiris JS. Influenza associated mortality in the subtropics and tropics: Results from three Asian cities. Vaccine. 2011 Nov 8;29(48):8909-14. Epub 2011 Sep 28. PubMed PMID: 21959328 (Impact Factor: 3.8).
  204. Wong CM, Peiris JS, Yang L, Chan KP, Thach TQ, Lai HK, Lim WW, Hedley AJ, He J, Chen P, Ou C, Deng A, Zhang X, Zhou D, Ma S, Chow A. Effect of influenza on cardiorespiratory and all-cause mortality in Hong Kong, Singapore and Guangzhou. Hong Kong Med J. 2012 Feb;18 Suppl 2:8-11 (Impact Factor: 0.1)
  205. Wong CM, Yang L, Chan KP, Chan WM, Song L, Lai HK, Thach TQ, Ho LM, Chan KH, Lam TH, Peiris JS. Cigarette smoking as a risk factor for influenza-associated mortality: evidence from an elderly cohort. Influenza Other Respir Viruses. 2013 Jul;7(4):531-9. doi: 10.1111/j.1750-2659.2012.00411.x. Epub 2012 Jul 20 (Impact Factor: 4.2)
  206. Yang L, Chan KP, Lee SY, Chan WM, Lai HK, Thach TQ, Chan KH, Lam TH, Peiris JSM, Wong CM. Obesity and influenza associated mortality: evidence from an elderly cohort in Hong Kong. Prev Med. 2013 Feb;56(2):118-23. doi: 10.1016/j.ypmed.2012.11.017. (Impact Factor: 3.5)
  207. Lam EH, Cowling BJ, Cook AR, Wong JY, Lau MS, Nishiura H. The feasibility of age-specific travel restrictions during influenza pandemics. Theor Biol Med Model. 2011 Nov 11;8:44. (Impact Factor: 1.9)
  208. Wu P, Cowling BJ, Wu JT, Lau EHY, Ip DKM, Nishiura H. The epidemiological and public health research response to 2009 pandemic influenza A(H1N1): experiences from Hong Kong. Influenza Other Respir Viruses. 2013 May;7(3):367-82. doi: 10.1111/j.1750-2659.2012.00420.x. Epub 2012 Aug 9. (Impact Factor: 1.5)
  209. Lessler J, Cummings DA, Read JM, Wang S, Zhu H, Smith GJ, Guan Y, Jiang CQ, Riley S. Location-specific patterns of exposure to recent pre-pandemic strains of influenza A in southern China. Nat Commun. 2011 Aug 9;2:423. doi: 10.1038/ncomms1432. (Impact Factor: 7.4)
  210. Leung YH, Lau EH, Zhang LJ, Guan Y, Cowling BJ, Peiris JS. Avian influenza and ban on overnight poultry storage in live poultry markets, Hong Kong. Emerg Infect Dis. 2012 Aug;18(8):1339-41. doi: 10.3201/eid1808.111879. (Impact Factor: 6.2)
  211. Oei W, Nishiura H. The relationship between tuberculosis and influenza death during the influenza (H1N1) pandemic from 1918-19. Comput Math Methods Med. 2012;2012:124861. doi: 10.1155/2012/124861. Epub 2012 Jul 17. (Impact Factor: 0.7)
  212. Zhou Y, Ng DM, Seto WH, Ip DK, Kwok HK, Ma ES, Ng S, Lau LL, Peiris JS, Cowling BJ. Seroprevalence of pandemic H1N1 antibody among health care workers in Hong Kong following receipt of monovalent 2009 H1N1 influenza vaccine. PLoS One. 2011;6(11):e27169. (Impact Factor: 4.1)
  213. Ng S, Wu P, Nishiura H, Ip DK, Lee ES, Cowling BJ. An analysis of national target groups for monovalent 2009 pandemic influenza vaccine and trivalent seasonal influenza vaccines in 2009-10 and 2010-11. BMC Infect Dis. 2011 Aug 26;11:230. (Impact Factor: 3.1)
  214. Goldstein E, Cowling BJ, Aiello AE, Takahashi S, King G, Lu Y, Lipsitch M. Estimating incidence curves of several infections using symptom surveillance data. PLoS One. 2011;6(8):e23380. Epub 2011 Aug 24. (Impact Factor: 4.1)
  215. Wu P, Goldstein E, Ho LM, Yang L, Nishiura H, Wu JT, Ip DKM, Chuang SK, Tsang T, Cowling BJ. Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. J Infect Dis. 2012 Dec 15;206(12):1862-71. doi: 10.1093/infdis/jis628. Epub 2012 Oct 8. (Impact Factor: 5.9)
  216. Ng S, Fang VJ, Ip DK, Chiu SS, Leung GM, Peiris JS, Cowling BJ. Humoral antibody response after receipt of inactivated seasonal influenza vaccinations one year apart in children. Pediatr Infect Dis J. 2012 Sep;31(9):964-9. doi: 10.1097/INF.0b013e318263280e. (Impact Factor: 3.6)

    2013


  217. Cowling BJ, Ip DK, Fang VJ, Suntarattiwong P, Olsen SJ, Levy J, Uyeki TM, Leung GM, Malik Peiris JS, Chotpitayasunondh T, Nishiura H, Mark Simmerman J. Aerosol transmission is an important mode of influenza A virus spread. Nat Commun. 2013;4:1935. doi: 10.1038/ncomms2922. (Impact Factor: 10.02 )
  218. Ng S, Fang VJ, Ip DKM, Chan KH, Leung GM, Peiris JSM, Cowling BJ. Estimation of the association between antibody titers and protection against confirmed influenza virus infection in children. Journal of Infectious Diseases, 2013; 208:1320-4. (Impact Factor: 6.4)
  219. Lau LL, Ip DK, Nishiura H, Fang VJ, Chan KH, Peiris JS, Leung GM, Cowling BJ. Heterogeneity in viral shedding among individuals with medically attended influenza A virus infection. J Infect Dis. 2013 Apr 15;207(8):1281-5. doi: 10.1093/infdis/jit034. (Impact Factor: 5.85 )
  220. Zhou Y, Lau EHY, Ip DKM, Nishiura H, Leung GM, Seto WH, Cowling BJ. Years of life lost in the first wave of 2009 pandemic (H1N1) in Hong Kong. American Journal of Epidemiology, 2013; 178(8):1313-8. (Impact Factor: 5.2)
  221. Wu P, Cowling BJ, Wu JT, Lau EH, Ip DK, Nishiura H. The epidemiological and public health research response to 2009 pandemic influenza A(H1N1): experiences from Hong Kong. Influenza Other Respir Viruses. 2013 May;7(3):367-82. doi: 10.1111/j.1750-2659.2012.00420.x. (Impact Factor: 4.2)
  222. Ng S, Ip DK, Fang VJ, Chan KH, Chiu SS, Leung GM, Peiris JS, Cowling BJ. The effect of age and recent influenza vaccination history on the immunogenicity and efficacy of 2009-10 seasonal trivalent inactivated influenza vaccination in children. PLoS One. 2013;8(3):e59077. doi: 10.1371/journal.pone.0059077. (Impact Factor: 3.73)
  223. Cheng KYC, Channarith H, Cowling BJ. Potential use of school absenteeism record for disease surveillance in developing countries, case study in rural Cambodia. PLoS ONE, 2013; 8(10): e76859. (Impact Factor: 4.1)
  224. Wong JY, Kelly H, Ip DK, Wu JT, Leung GM, Cowling BJ. Case fatality risk of influenza A (H1N1pdm09): a systematic review. Epidemiology. 2013 Nov;24(6):830-41. doi: 10.1097/EDE.0b013e3182a67448. (Impact Factor: 5.6)
  225. Nishiura H, Yen HL, Cowling BJ. Sample size considerations for one-to-one animal transmission studies of the influenza A viruses. PLoS ONE, 2013; 8(1):e55358. (Impact Factor: 4.1)
  226. Ejima, K, Aihara, K, Nishiura, H. On the use of chance-adjusted agreement statistic to measure the assortative transmission of infectious diseases. Computational & Applied Mathematics 32(2): 303-313. DOI: 10.1007/s40314-013-0017-7 (Impact Factor: 0.45) 
  227. Mizumoto K, Nishiura H, Yamamoto T. Effectiveness of antiviral prophylaxis coupled with contact tracing in reducing the transmission of the influenza A (H1N1-2009): a systematic review. Theor Biol Med Model. 2013 Jan 16;10:4. doi: 10.1186/1742-4682-10-4. (Impact Factor: 1.46)
  228. Mizumoto K, Yamamoto T, Nishiura H. Age-dependent estimates of the epidemiological impact of pandemic influenza (H1N1-2009) in Japan. Comput Math Methods Med. 2013;2013:637064. doi: 10.1155/2013/637064. (Impact Factor: Nil)
  229. Van Kerkhove MD, Broberg E, Engelhardt OG, Wood J, Nicoll A and CONSISE steering committee (includes Cowling BJ and Peiris M). The consortium for the standardization of influenza seroepidemiology (CONSISE): a global partnership to standardize influenza seroepidemiology and develop influenza investigation protocols to inform public health policy. Influenza Other Respir Viruses. 2013 May;7(3):231-4.(Impact Factor: 1.89 (2013))
  230. Yu H, Wu JT, Cowling BJ, Liao Q, Fang VJ, Zhou S, Wu P, Zhou H, Lau EH, Guo D, Ni MY, Peng Z, Feng L, Jiang H, Luo H, Li Q, Feng Z, Wang Y, Yang W, Leung GM. Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study. Lancet. 2013 Oct 30. doi:pii: S0140-6736(13)61904-2. (Impact Factor: 39.2 (2013))
  231. Cowling BJ, Jin L, Lau EH, Liao Q, Wu P, Jiang H, Tsang TK, Zheng J, Fang VJ, Chang Z, Ni MY, Zhang Q, Ip DK, Yu J, Li Y, Wang L, Tu W, Meng L, Wu JT, Luo H, Li Q, Shu Y, Li Z, Feng Z, Yang W, Wang Y, Leung GM, Yu H. Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet, 2013; 382(9887):129-37. (Impact Factor: 39.0)
  232. Yu H, Cowling BJ, Feng L, Lau EH, Liao Q, Tsang TK, Peng Z, Wu P, Liu F, Fang VJ, Zhang H, Li M, Zeng L, Xu Z, Li Z, Luo H, Li Q, Feng Z, Cao B, Yang W, Wu JT, Wang Y, Leung GM. Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet, 2013; 382(9887):138-45. (Impact Factor: 39.0)
  233. Ip DK, Liao Q, Wu P, Gao Z, Cao B, Feng L, Xu X, Jiang H, Li M, Bao J, Zheng J, Zhang Q, Chang Z, Li Y, Yu J, Liu F, Ni MY, Wu JT, Cowling BJ, Yang W, Leung GM, Yu H. Detection of mild to moderate influenza A/H7N9 infection by China's national sentinel surveillance system for influenza-like illness: case series. BMJ, 2013; 346:f3693. (Impact Factor: 17.2)
  234. Cowling BJ, Freeman G, Wong JY, Wu P, Liao Q, Lau EH, Wu JT, Fielding R, Leung GM. Preliminary inferences on the age-specific seriousness of human disease caused by avian influenza A(H7N9) infections in China, March to April 2013. Eurosurveillance, 2013; 18(19):pii=20475. (Impact Factor: 6.2)

    2014


  235. Ng S, Ni MY, Fang VJ, Ip DK, Chan KH, Leung GM, Peiris JS, Cowling BJ. Characteristics of vaccine failures in a randomized placebo-controlled trial of inactivated influenza vaccine in children. Pediatr Infect Dis J. 2014 Feb;33(2):e63-6. doi: 10.1097/INF.0000000000000064. (Impact Factor: 3.57 (2012))
  236. Liao Q, Cowling BJ, Lam WW, Ng DM, Fielding R. Anxiety, worry and cognitive risk estimate in relation to protective behaviors during the 2009 influenza A/H1N1 pandemic in Hong Kong: ten cross-sectional surveys. BMC Infect Dis. 2014 Mar 27;14:169. doi: 10.1186/1471-2334-14-169. (Impact Factor: 3.03 (2012))
  237. Chan KP, Wong CM, Chiu SS, Chan KH, Wang XL, Chan EL, Peiris JS, Yang L. A robust parameter estimation method for estimating disease burden of respiratory viruses. PLoS One. 2014 Mar 20;9(3):e90126. doi: 10.1371/journal.pone.0090126. eCollection 2014. (Impact Factor: 3.73 (2012))
  238. Wang XL, Wong CM, Chan KH, Chan KP, Cao PH, Peiris JM, Yang L. Hospitalization risk of the 2009 H1N1 pandemic cases in Hong Kong. BMC Infect Dis. 2014 Jan 16;14:32. doi: 10.1186/1471-2334-14-32. (Impact Factor: 3.03 (2012))
  239. Wu P, Goldstein E, Ho LM, Wu JT, Tsang T, Leung GM, Cowling BJ. Excess mortality impact of two epidemics of pandemic influenza A(H1N1pdm09) virus in Hong Kong. Influenza Other Respir Viruses. 2014 Jan;8(1):1-7. doi: 10.1111/irv.12196. Epub 2013 Nov 7. (Impact Factor: 1.47 (2012))
  240. Wu JT, Leung K, Perera RA, Chu DK, Lee CK, Hung IF, Lin CK, Lo SV, Lau YL, Leung GM, Cowling BJ, Peiris JS. Inferring influenza infection attack rate from seroprevalence data. PLoS Pathog. 2014 Apr 3;10(4):e1004054. doi: 10.1371/journal.ppat.1004054. eCollection 2014 Apr. PubMed PMID: 24699693; PubMed Central PMCID: PMC3974861. (Impact Factor: 8.1 (2013))
  241. Cowling BJ, Perera RA, Fang VJ, Chan KH, Wai W, So HC, Chu DK, Wong JY, Shiu EY, Ng S, Ip DK, Peiris JS, Leung GM. Incidence of influenza virus infections in children in Hong Kong in a 3-year randomized placebo-controlled vaccine study, 2009-2012. Clin Infect Dis. 2014 Aug 15;59(4):517-24. doi: 10.1093/cid/ciu356. Epub 2014 May 13. PubMed PMID: 24825868. (Impact Factor: 9.4 (2013))
  242. Liao Q, Ip DKM, Tsang TK, Cao B, Jiang H, Liu F, Zheng J, Peng Z, Wu P, Huai Y, Lau EHY, Feng L, Leung GM, Yu H, Cowling BJ. A clinical prediction rule for diagnosing human infections with avian influenza A(H7N9) in a hospital emergency department setting. BMC Medicine, 2014; 12(1):127. PMID: 25091477 (Impact factor: 7.3 (2013))
  243. Wang L, Cowling BJ†, Wu P, Yu J, Li F, Zeng L, Wu JT, Li Z, Leung GM, Yu H. Human exposure to live poultry and psychological and behavioral responses to influenza A(H7N9), China. Emerging Infectious Diseases, 2014; 20(8): 1296-305. PMID: 25076186 (Impact factor: 7.33 (2013))
  244. Lau EH, Zheng J, Tsang TK, Liao Q, Lewis B, Brownstein JS, Sanders S, Wong JY, Mekaru SR, Rivers C, Wu P, Jiang H, Li Y, Yu J, Zhang Q, Chang Z, Liu F, Peng Z, Leung GM, Feng L, Cowling BJ, Yu H. Accuracy of epidemiological inferences based on publicly available information: retrospective comparative analysis of line lists of human cases infected with influenza A(H7N9) in China. BMC Medicine, 2014; 12(1):88. PMID: 24885692 (Impact factor: 7.3 (2013))
  245. Cowling BJ, Ip DKM, Fang VJ, Suntarattiwong P, Olsen SJ, Levy J, Uyeki TM, Leung GM, Peiris JSM, Chotpitayasunondh T, Nishiura H, Simmerman JM. Modes of transmission of influenza B virus in households. PLoS ONE, 2014; 9(9):e108850. PMID: 25268241 (Impact factor: 3.5 (2013))
  246. Cowling BJ, Chan KH, Feng S, Chan EL, Lo JY, Peiris JS, Chiu SS. The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009-2013. Vaccine, 2014; 32(41):5278-84. PMID: 25092636 (Impact factor: 3.49 (2013))
  247. Wu P, Jiang H, Wu JT, Chen E, He J, Zhou H, Wei L, Yang J, Yang B, Qin Y, Fang VJ, Li M, Tsang TK, Zheng J, Lau EHY, Cao Y, Chai C, Zhong H, Li Z, Leung GM, Feng L, Gao GF, Cowling BJ†, Yu H. Poultry market closures and human infection with influenza A(H7N9) virus, China, 2013-14. Emerging Infectious Diseases, 2014 Nov;20(11):1891-4. doi: 10.3201/eid2011.140556. PMID: 25340354. (Impact factor: 7.33 (2013))
  248. Wong JY, Wu P, Goldstein E, Lau EHY, Ip DKM, Wu JT, Cowling BJ. Analysis of potential changes in seriousness of influenza A and B viruses in Hong Kong from 2001 to 2011. Epidemiology and Infection, 2014 (in press). (Impact factor: 2.5 (2013))
  249. Freeman G, Ng S, Perera RAPM, Fang VJ, Ip DKM, Leung GM, Peiris JSM, Cowling BJ. Multivariate analysis of factors affecting the immunogenicity of trivalent inactivated influenza vaccine in school-age children. Epidemiology and Infection, 2014 (in press). PMID: 24786933 (Impact factor: 2.5 (2013))
  250. Tsang TK, Cauchemez S, Perera RAPM, Freeman G, Fang VJ, Ip DKM, Leung GM, Peiris JSM, Cowling BJ. Association between antibody titers and protection against influenza virus infection within households. Journal of Infectious Diseases, 2014 (in press). PMID: 24676208 (Impact factor: 5.8 (2013))
  251. Malik R, Deardon R, Kwong GPS, Cowling BJ. Individual-level modeling of the spread of influenza within households. Journal of Applied Statistics, 2014; 41(7):1578-92. (Impact factor: 0.45 (2013))
  252. Wu P, Fang VJ, Liao Q, Ng DMW, Wu JT, Leung GM, Fielding R, Cowling BJ. Responses to threat of influenza A(H7N9) and support for live poultry markets, Hong Kong, 2013. Emerging Infectious Diseases, 2014; 20(5):882-6. PMID: 24750988 (Impact factor: 7.33 (2013))
  253. Klick B, Nishiura H, Leung GM, Cowling BJ. Optimal design of studies of influenza trans- mission in households. II: Comparison between cohort and case-ascertained studies. Epidemiology and Infection, 2014; 142(4): 744-52. PMID: 23830470 (Impact factor: 2.5 (2013))
  254. Ying Z, Ali A, Cowling BJ, Stoto MA. Characterizing Influenza surveillance systems perfor- mance: application of a Bayesian hierarchical statistical model to Hong Kong surveillance data. BMC Public Health, 2014; 14(1):850. PMID: 25127906 (Impact factor: 2.32 (2013))
  255. Kwok KO, Cowling BJ, Wei VW, Wu KM, Read JM, Lessler J, Cummings DA, Peiris JS, Riley S. Social contacts and the locations in which they occur as risk factors for influenza infection. Proceedings of the Royal Society B: Biological Sciences, 2014; 281(1789). pii: 20140709. PMID: 25009062
  256. Chiu SS, Lo JY, Chan KH, Chan EL, So LY, Wu P, Cowling BJ, Chen R, Peiris JS. Population- based hospitalization burden of influenza A virus subtypes and antigenic drift variants in children in Hong Kong (2004-2011). PLoS ONE, 2014; 9(4):e92914. PMID: 24786780 (Impact factor: 3.5 (2013))
  257. Patterson-Lomba O, Van Noort S, Cowling BJ, Wallinga J, Gomes MG, Lipsitch M, Goldstein E. Utilizing syndromic surveillance data for estimating levels of influenza circulation. Am J Epidemiol. 2014 Jun 1;179(11):1394-401. doi: 10.1093/aje/kwu061. Epub 2014 Apr 18. PMID: 24748609 (Impact factor: 4.98 (2013))
  258. Wong VW, Cowling BJ, Aiello AE. Hand hygiene and risk of influenza virus infections in the community: a systematic review and meta-analysis. Epidemiol Infect. 2014 May;142(5):922-32. doi: 10.1017/S095026881400003X. Epub 2014 Jan 24. PMID: 24572643 (Impact factor: 2.5 (2013))
  259. Wang X, Fang S, Lu X, Xu C, Cowling BJ, Tang X, Peng B, Wu W, He J, Tang Y, Xie X, Mei S, Kong D, Zhang R, Ma H, Cheng J. Seroprevalence to avian influenza A(H7N9) virus among poultry workers and the general population in southern China: a longitudinal study. Clinical Infectious Diseases, 2014 (in press). PMID: 24867786 (Impact factor: 9.42 (2013))
  260. Ma X, Liao Q, Yuan J, Liu Y, Liu Y, Chen J, Liu J, Cai W, Cowling BJ, Di B, Fielding R, Wang M, Yang Z, Leung GM, Lau EH. Knowledge, attitudes and practices relating to influenza A(H7N9) risk among live poultry traders in Guangzhou City, China. BMC Infect Dis. 2014 Oct 18;14:554. doi:10.1186/s12879-014-0554-8. PubMed PMID: 25324011; PubMed Central PMCID: PMC4210513. (Impact factor: 2.56 (2013))

    Antivirals and Therapeutics:


    2008 - May 2011


  261. Kao RY, Yang D, Lau LS, Tsui WH, Hu L, Dai J, Chan MP, Chan CM, Wang P, Zheng BJ, Sun J, Huang JD, Madar J, Chen G, Chen H, Guan Y, Yuen KY. Identification of influenza A nucleoprotein as an antiviral target. Nat Biotechnol. 2010 Jun;28(6):600-5. Epub 2010 May 30. (Impact factor: 29.5)
  262. An J, Lee DC, Law AH, Yang CL, Poon LL, Lau AS, Jones SJ. A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase. J Med Chem. 2009 May 14;52(9):2667-72. (Impact factor: 4.8)
  263. Linda S M Ooi, Wing-Shan Ho, Karry L K Ngai, Li Tian, Paul K S Chan, Samuel S M Sun, Vincent E C Ooi. Narcissus tazetta lectin shows strong inhibitory effects against respiratory syncytial virus , influenza A (H1N1, H3N2, H5N1) and B viruses J. Biosci. 35(1), March 2010, 00–00 (Impact factor: 2)

    Jun 2011- 2012


  264. Wu WL, Lau SY, Chen Y, Wang G, Mok BW, Wen X, Wang P, Song W, Lin T, Chan KH, Yuen KY, Chen H. The 2008-2009 H1N1 influenza virus exhibits reduced susceptibility to antibody inhibition: Implications for the prevalence of oseltamivir resistant variant viruses. Antiviral Res. 2012 Jan;93(1):144-53. Epub 2011 Nov 25. (Impact Factor: 4.3)
  265. Wong DD, Choy KT, Chan RW, Sia SF, Chiu HP, Cheung PP, Chan MC, Peiris JS, Yen HL. Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation. J Virol. 2012 Oct;86(19):10558-70. doi: 10.1128/JVI.00985-12. Epub 2012 Jul 18. (Impact Factor: 5.4)
  266. Lee SM, Gai WW, Cheung TK, Peiris JS. Antiviral effect of a selective COX-2 inhibitor on H5N1 infection in vitro. Antiviral Res. 2011 Sep;91(3):330-4. Epub 2011 Jul 21. PubMed PMID: 21798291. (Impact Factor: 4.3)
  267. Chan LY, Kwok HH, Chan RW, Peiris MJ, Mak NK, Wong RN, Chan MC, Yue PY. Dual functions of ginsenosides in protecting human endothelial cells against influenza H9N2-induced inflammation and apoptosis. J Ethnopharmacol. 2011 Oct 11;137(3):1542-6. Epub 2011 Aug 22. (Impact Factor: 3.0)
  268. Lee, S.M.Y. and H.-L. Yen. 2012. Targeting the host or the virus: Current and novel concepts for antiviral approaches against influenza virus infection. Antiviral Res. 2012 Dec;96(3):391-404. doi: 10.1016/j.antiviral.2012.09.013. Epub 2012 Sep 26. (Impact Factor: 3.93)

    2014


  269. Mok CK, Kang SS, Chan RW, Yue PY, Mak NK, Poon LL, Wong RN, Peiris JS, Chan MC. Anti-inflammatory and antiviral effects of indirubin derivatives in influenza A (H5N1) virus infected primary human peripheral blood-derived macrophages and alveolar epithelial cells. Antiviral Res. 2014 Apr 6;106C:95-104. doi: 10.1016/j.antiviral.2014.03.019. [Epub ahead of print] (Impact Factor: 3.93 (2012))
  270. Yen HL, Zhou J, Choy KT, Sia SF, Teng O, Ng IH, et al. The R292K Mutation That Confers Resistance to Neuraminidase Inhibitors Leads to Competitive Fitness Loss of A/Shanghai/1/2013 (H7N9) Influenza Virus in Ferrets. J Infect Dis. 2014 Jun 20. PubMed PMID: 24951824. (Impact Factor: 5.78 (2013))

    Vaccines, passive immunotherapy and immunotherapy:


    2008 – May 2011


  271. Poon LLM, Leung YHC, Nicholls JM, Perera PY, Lichy JH, Yamamoto L, Waldmann TA, Peiris JSM, Perera LP. Vaccinia Virus-Based Multivalent H5N1 Avian Influenza Vaccines Adjuvanted with IL-15 Confer Sterile Cross-Clade Protection in Mice. J. Immunol., Mar 2009; 182: 3063 – 3071. (Impact factor: 6)
  272. Zhao, GY, Lin, YP, Du, LY, Guan J, Sun, SH, Sui HY, Kou ZH, Chan CCS, Guo Y, Jiang SB, Zheng BJ, Zhou YS. An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses. Virology Journal 2010; January, Art No 9. (Impact factor: 2.4)
  273. Zhao G, Du L, Xiao W, Sun S, Lin Y, Chen M, Kou Z, He Y, Lustigman S, Jiang S, Zheng BJ, Zhou Y. Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvant. Vaccine. 2010; 28:7233-40. (Impact factor: 3.6)
  274. Throsby M, van den Brink E, Jongeneelen M, Poon LL, Alard P, Cornelissen L, Bakker A, Cox F, van Deventer E, Guan Y, Cinatl J, ter Meulen J, Lasters I, Carsetti R, Peiris M, de Kruif J, Goudsmit J. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS ONE. 2008;3(12):e3942. Epub 2008 Dec 16 (Impact factor: 4.4)
  275. Wu WL, Chen Y, Wang P, Song W, Lau SY, Rayner JM, Smith GJ, Webster RG, Peiris JS, Lin T, Xia N, Guan Y, Chen H. Antigenic profile of avian H5N1 viruses in Asia from 2002 to 2007. J Virol. 2008 Feb;82(4):1798-807. (Impact factor: 5.2)
  276. Chen Y, Qin K, Wu WL, Li G, Zhang J, Du H, Ng MH, Shih JW, Peiris JS, Guan Y, Chen H, Xia N. Broad Cross-Protection against H5N1 Avian Influenza Virus Infection by Means of Monoclonal Antibodies that Map to Conserved Viral Epitopes. J Infect Dis. 2009 Jan 1;199(1):49-5 (Impact factor: 5.9)
  277. Zheng Q, Xia L, Wu WL, Zheng Z, Huo Y, Wu J, Liu Y, Yu H, Chen Y, Lau SY, Chen H, Luo W, Xia N Properties and therapeutic efficacy of broadly reactive chimeric and humanized H5-specific monoclonal antibodies against H5N1 influenza viruses. Antimicrob Agents Chemother 2011 Apr;55(4):1349-57. (Impact factor: 4.45 (2013))
  278. Chen Y, W Luo, W L Wu, Z Fang, L Xia, X Gui, Y Chen, H Chen, J. W-K Shih, N Xia (2010).Humanized Antibodies with Broad-Spectrum Neutralization to Avian Influenza Virus H5N1. Antiviral Research 87(1):81-4. (Impact factor 3.5)
  279. Chua TH, Leung CYH, Fang HE, Chow CK, Ma SK, Sia SF, Ng IHY, Fenwick SG, James CM, Chua SB, Chew ST, Kwang J, Peiris JSM, Ellis TM. Evaluation of a Subunit H5 Vaccine and an Inactivated H5N2 Avian Influenza Marker Vaccine in Ducks Challenged with Vietnamese H5N1 Highly Pathogenic Avian Influenza Virus. Influenza Research and Treatment Volume 2010, Article ID 489213, doi:10.1155/2010/489213. (Pending Impact factor).
  280. Tu WW, Zheng J, Liu Y, Sia SF, Liu M, Qin G, Ng IHY, Lam KT, Peiris JSM, Lau YL. The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice. J Exp Med. 2011 Jul 4;208(7):1511-22. doi: 10.1084/jem.20110226. Epub 2011 Jun 27 (Impact factor: 13.2)

    Jun 2011 – 2012


  281. Ekiert DC, Friesen RH, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJ, Brandenburg B, Vogels R, Brakenhoff JP, Kompier R, Koldijk MH, Cornelissen LA, Poon LL, Peiris M, Koudstaal W, Wilson IA, Goudsmit J. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science. 2011 Aug 12;333(6044):843-50. Epub 2011 Jul 7. (Impact Factor: 31.2)
  282. Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin Ö, Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH. Highly conserved protective epitopes on influenza B viruses. Science. 2012 Sep 14;337(6100):1343-8. (Impact Factor: 31.2)

    2013


  283. Connie Leung YH, Luk G, Sia SF, Wu YO, Ho CK, Chow KC, Tang SC, Guan Y, Malik Peiris JS. 2013. Experimental challenge of chicken vaccinated with commercially available H5 vaccines reveals loss of protection to some highly pathogenic avian influenza H5N1 strains circulating in Hong Kong/China. Vaccine. 2013 Aug 2;31(35):3536-42. doi: 10.1016/j.vaccine.2013.05.076. (Impact Factor: 3.49)

    2014


  284. Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, Waldmann TA, Peiris JS, Perera LP, Poon LL. IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5676-81. doi: 10.1073/pnas.1403684111. Epub 2014 Mar 31. (Impact Factor: 9.7 (2012))

    Commentaries, major reviews and book chapters:


    2008 - June 2011


  285. Peiris JS, Poon LL, Guan Y. Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans. J Clin Virol. 2009 Jul;45(3):169-73. Epub 2009 Jun 11 (Impact factor 3.3).
  286. Li OT, Poon LL. One step closer to universal influenza epitopes. Expert Rev Anti Infect Ther. 2009 Aug;7(6):687-90 (Impact factor: 3.06 (2013))
  287. Yen HL, Peiris JS Mapping antibody epitopes of the avian H5N1 influenza virus PloS Med. 2009 Apr 21;6(4):e1000064. Epub 2009 Apr 21. (Impact factor: 13.05)
  288. Peiris JS, Cheung CY, Leung CY, Nicholls JM. Innate immune responses to influenza A H5N1: friend or foe? Trends Immunol. 2009 Oct 26 (Impact factor: 8.8)
  289. Peiris JS, Tu WW, Yen HL. A novel H1N1 virus causes the first pandemic of the 21(st) century. Eur J Immunol. 2009 Sep 29;39(11):2946-2954. (Impact factor: 5.2 )
  290. Peiris JSM. Avian influenza viruses in humans. Rev. sci.tech.Off.int. Epiz. 2009, 28: (1), 161-174.(impact Factor: 1.24)
  291. Peiris JS, Hui KP, Yen HL. Host response to influenza virus: protection versus immunopathology. Curr Opin Immunol 2010 Aug;22(4):475-81. Epub 2010 Jun 30. (Impact factor: 10.9)
  292. Garcia JM, Lai JC. Production of influenza pseudotyped lentiviral particles and their use in influenza research and diagnosis: an update. Expert Rev Anti Infect Ther. 2011 Apr;9(4):443-55. (Impact Factor: 3.3)

    June 2011 – Dec 2012


  293. Peiris JS, Poon LL, Guan Y. Public health. Surveillance of animal influenza for pandemic preparedness. Science. 2012 Mar 9;335(6073):1173-4. (Impact Factor: 31.2)
  294. Yen, H. L. and J. S. M. Peiris. Virology: Bird flu in mammal. Nature. Volume: 486, Pages: 332–333 Date published: (21 June 2012) DOI: doi:10.1038/nature11192. (Commentary, acknowledgements not permitted). (Impact Factor: 36.3)
  295. Guan Y, Webby R, Capua I, Waldenström J. H5N1: How to track a flu virus. Nature. 2012 Mar 28;483(7391):535-6. doi: 10.1038/483535a. (Commentary, grant acknowledgments not permitted). (Impact Factor: 36.3)
  296. Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz J, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG. Pause on avian flu transmission research. Science. 2012 Jan 27;335(6067):400-1. (Comment, acknowledgements not permitted). (Impact Factor: 31.2)
  297. Sims LD, Peiris M. One Health: The Hong Kong Experience with Avian Influenza. Curr Top Microbiol Immunol. 2012 Aug 18. [Epub ahead of print] (Impact Factor: 4.9)
  298. Lee SM, Dutry I, Peiris JS. Editorial: macrophage heterogeneity and responses to influenza virus infection. J Leukoc Biol. 2012 Jul;92(1):1-4. (Impact Factor: 5.0)
  299. Garcia JM, Lai JC. Production of influenza pseudotyped lentiviral particles and their use in influenza research and diagnosis: an update. Expert Rev Anti Infect Ther. 2011 Apr;9(4):443-55. doi: 10.1586/eri.11.25. (Impact factor: 2.1)
  300. Li X. Click to join peptides/proteins together. Chem Asian J. 2011 Oct;6(10):2606-16. (Impact Factor: 4.5)
  301. Zheng J, Liu Y, Lau YL, Tu W. γδ-T cells: an unpolished sword in human anti-infection immunity. Cell Mol Immunol. 2013 Jan;10(1):50-7. doi: 10.1038/cmi.2012.43. (Impact Factor: 3.42)
  302. Mak PW, Jayawardena S, Poon LL. The evolving threat of influenza viruses of animal origin and the challenges in developing appropriate diagnostics. Clin Chem. 2012 Nov;58(11):1527-33. (Impact Factor: 7.9)
  303. Klick B, Leung GM, Cowling BJ. Optimal design of studies of influenza transmission in households I: case-ascertained studies. Epidemiol Infect. 2012 Jan;140(1):106-14. (Impact Factor: 2.87)

    2013


  304. Fouchier RAM, Guan Y. In eds. RG Webster, AS Monto, TJ Braciale, RA Lamb. Ecology and evolution of influenza viruses in wild and domestic birds. Textbook of Influenza, 2nd Edition, Wiley Blackwell, London, 2013; Chapter 11; pp175-189.
  305. Iwasaki A, Peiris M. In eds. RG Webster, AS Monto, TJ Braciale, RA Lamb. Innate Immunity. Textbook of Influenza, 2nd Edition, Wiley Blackwell, London, 2013; Chapter 17; pp 231-249.
  306. Fouchier RA, Kawaoka Y, Cardona C, Compans RW, Fouchier RA, García-Sastre A, Govorkova EA, Guan Y, Herfst S, Kawaoka Y, Orenstein WA, Peiris JS, Perez DR, Richt JA, Russell C, Schultz-Cherry SL, Smith DJ, Steel J, Tompkins SM, Topham DJ, Treanor JJ, Tripp RA, Webby RJ, Webster RG. 2013. Avian flu: Gain-of-function experiments on H7N9. Nature 500(7461):150-151. (Impact Factor: 38.6)
  307. Fouchier RA, Kawaoka Y, Cardona C, Compans RW, García-Sastre A, Govorkova EA, Guan Y, Herfst S, Orenstein WA, Peiris JS, Perez DR, Richt JA, Russell C, Schultz-Cherry SL, Smith DJ, Steel J, Tompkins SM, Topham DJ, Treanor JJ, Tripp RA, Webby RJ, Webster RG. 2013. Gain-of-function experiments on H7N9. Science 341(6146):612-613. (Impact Factor: 31.03)
  308. To KK, Chan JF, Chen H, Li L, Yuen KY(2013) The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities. Lancet Infect Dis. 2013 Sep;13(9):809-21. doi: 10.1016/S1473-3099(13)70167-1. (Impact Factor: 19.97)